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'Icy' technique improves robotic kidney transplants
A collaboration of surgeons at Henry Ford Hospital and Medanta Hospital in India successfully transplanted kidneys into 50 recipients using an innovative robot-assisted procedure in which the organ is cooled with sterile ice during the operation.
The research project – published online ahead of print in European Urology, the journal of the European Association of Urology – advances minimally invasive robotic surgery as a safe alternative to traditional open surgery.
2014 ASTS Research Grants: One week left!
ASTS research grant applications must be submitted by Tuesday, Feb. 4, 2014. Complete eligibility requirements and the applications are available online at ASTS.org.
Thanks for making this Winter Symposium the best ever!
Thanks to everyone who attended the 14th Annual State of the Art Winter Symposium! More than 500 attendees helped make this the most successful symposium to date. Please join us January 15-18, 2015, at the Loews Miami Beach Hotel for next year's meeting, Transplant: The Ultimate Team Sport!
Reminder: Have you paid your dues?
ASTS members should have received their membership renewal invoices via email late last year. Dues payments were due at the end of the year, but you can still pay online and ensure your continued access to the wide range of ASTS member benefits, including your AJT subscription and discounted registration to events like the 2014 WTC. You can log on to the ASTS website anytime to pay your dues.
Revisiting multi-organ transplantation in the setting of scarcity
American Journal of Transplantation
In the setting of organ scarcity, the ethics of multi-organ transplantation (MOT) deserve new examination. MOT offers substantial benefits to certain recipients, including avoiding serial surgeries. However, MOT candidates in the United States commonly receive priority for their nonprimary organ over many individuals who need that organ, which may undermine equity.
Acute cellular rejection: Impact of donor-specific antibodies and C4d
Transplantation (login required)
Mixed rejection in kidney transplantation consists of histologic and/or serological evidence of both cellular and humoral components. As it is not confined to a distinct category in the Banff classification, how to best manage these patients is not clear. The aim of this study was to determine the incidence and outcome of morphological T-cell-mediated rejection (TCMR) with a humoral component, defined as the presence of either DSA or C4d, compared with the outcome of pure TCMR.
Utility of an immune cell function assay to differentiate rejection from infectious enteritis in pediatric intestinal transplant recipients
Clinical Transplantation (login required)
The Cylex Immune Cell Function Assay measures cell-mediated immunity based on ATP production by stimulated CD4+ cells. Authors of this study hypothesized that this test would discriminate acute cellular rejection from infectious enteritis in pediatric intestinal transplant recipients with allograft dysfunction.
MIT Technology Review
Since 2008, eight patients have been given a new chance at life when surgeons replaced their badly damaged tracheas with man-made versions. This highly experimental technology is now moving from research labs to a manufacturing facility as a Boston-area company prepares to produce the scaffolds for growing the synthetic organs on a large scale.
Morbidity higher in obese liver transplant recipients with diabetes, survival not impacted
Researchers from New Zealand report that morbidity following liver transplant is highest among obese patients with diabetes, but these risk factors do not influence post-transplant survival. According to the study published in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, body mass index (BMI) is effective for assessing obesity in liver transplant patients.
Penn, CHOP study reveals geography plays a major role in access to pediatric kidney transplantation
A new study from researchers at the Perelman School of Medicine at the University of Pennsylvania and the Children's Hospital of Philadelphia (CHOP) has revealed large geographic variation in waiting times for children across the United States in need of kidney transplants, with differences due mainly to local supply and demand.
T-cell migration to vascularized organ allografts
Current Opinion in Organ Transplantation (login required)
To review the classical paradigm of leukocyte migration and present new evidence that cognate antigen, and not signaling via Gαi-coupled chemokine receptors, drives the migration of effector and memory T cells into vascularized organ transplants.
George Washington Bridge a lifeline for organ transplants at hospitals
New York Daily News
Traffic on the busy span — which was jammed for days after N.J. Gov. Chris Christie's staff ordered lanes closed as part of a political vendetta — could mean the difference between life and death in operations such as heart transplants.
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