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Hepatitis C virus infection and kidney transplantation in 2014: What's new?
American Journal of Transplantation (login required)
Chronic hepatitis C virus infection remains an important health problem, which is associated with deleterious consequences in kidney transplant recipients. Besides hepatic complications, several extrahepatic complications contribute to reduced patient and allograft survival in HCV-infected kidney recipients. However, HCV infection should not be considered as a contraindication for kidney transplantation because patient survival is better with transplantation than on dialysis. Treatment of HCV infection is currently interferon-alpha (IFN-α) based, which has been associated with higher renal allograft rejection rates. Therefore, antiviral treatment before transplantation is preferable.
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SOCIETY NEWS


ASTS Recognition Awards nominations due Sept. 15
ASTS
Has a faculty member, mentor, or peer had a positive influence on your career? Say thank you by nominating them for an ASTS Recognition Award!
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Consensus conference on training in HBP Surgery
ASTS
ASTS, along with the American Hepato-Pancreato-Biliary Association and the Society of Surgical Oncology, will hold a consensus conference on training in HBP Surgery Oct. 27, 2014 at the Omni San Francisco.
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ASTS history book available
ASTS
If you weren't able to attend the World Transplant Congress and pick up the book chronicling the past 20 years of ASTS history, you can still get a copy! One free copy is available to ASTS members, and non-members can purchase a copy in the ASTS Store.
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TOP NEWS


FDA approves lung preservation machine
The Associated Press via ABC News
Federal health regulators have approved a novel device that can preserve donated lungs outside the body for possible transplantation into critically ill patients. The Food and Drug Administration said the approval of the XVIVO Perfusion System could lead to more successful transplants of lungs for people with cystic fibrosis and other deadly respiratory diseases.
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Indicators of treatment responsiveness to rituximab and plasmapheresis in antibody-mediated rejection after kidney transplantation
Transplantation (login required)
Treatment of patients with antibody-mediated rejection (AMR) after kidney transplantation by rituximab and plasmapheresis is ambiguous. Because of its unknown efficiency and serious side effects, biomarkers, which are predictive for responsiveness to this treatment in AMR patients, are required. Twenty renal transplant patients were included in this retrospective study. Selection was based on Renal Index Biopsies, classified according to Banff within 3 months before treatment. Patients were categorized into responders (R) and nonresponders (NR) depending on whether they returned to dialysis within 6 months after initiation of rituximab treatment.
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Child and family adjustment following pediatric solid organ transplantation: Factors to consider during the early years post-transplant
Pediatric Transplantation (login required)
Adjusting to life after transplant can be challenging to pediatric solid organ transplant recipients and their families. In this review, we discuss a number of important factors to consider during the first 2–3 years after transplant (defined as the "early years"), including transitioning from hospital to home, returning to physical activity, feeding and nutrition, school reentry, potential cognitive effects of transplant, family functioning, and QOL. We highlight steps that providers can take to optimize child and family adjustment during this period.
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Avoiding stay in the intensive care unit after liver transplantation: A score to assign location of care
American Journal of Transplantation (login required)
Select liver transplantation (LT) recipients in our program are transferred from operating room to postanesthesia care unit for recovery and extubation with transfer to the ward, completely eliminating an intensive care unit (ICU) stay. Developing a reliable method to determine patients suitable for fast-tracking would be of practical benefit to centers considering this practice. The aim of this study was to create a fast-tracking probability score that could be used to predict successful assignment of care location after LT.
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7 research developments in liver transplantation
Healio
Liver transplantation occurs when a damaged or failing liver is replaced with a healthy liver from a deceased or living donor through surgery. The latest research highlights certain risks and successes and addresses overall survival rate questions after transplantation. Here is a list of studies and recent news focusing on liver transplantation presented in Healio/Hepatology.
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Survival benefit of primary deceased donor transplantation with high-KDPI kidneys
American Journal of Transplantation (login required)
The Kidney Donor Profile Index, or KDPI, has been introduced as an aid to evaluating deceased donor kidney offers, but the relative benefit of high-KDPI kidney transplantation (KT) versus the clinical alternative (remaining on the waitlist until receipt of a lower KDPI kidney) remains unknown. Using time-dependent Cox regression, we evaluated the mortality risk associated with high-KDPI KT (KDPI 71–80, 81–90 or 91–100) versus a conservative, lower KDPI approach (remain on waitlist until receipt of KT with KDPI 0–70, 0–80 or 0–90) in first-time adult registrants, adjusting for candidate characteristics.
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TRENDING ARTICLES
Missed our previous issues? See which articles your colleagues read most.

    Consensus conference on training in HBP surgery (ASTS)
Through a glass darkly: Seeking clarity in preventing late kidney transplant failure (Journal of the American Society of Nephrology)
Management of hepatitis C in kidney transplant patients: On the cusp of change (American Journal of Transplantation)
UCSF 1st in nation to join with Walgreens in blood pressure testing program for living kidney donors, potential donors (UCSF)
Study: Liver transplants from living donors lead to better survival (By Karen Zabel)

Don't be left behind. Click here to see what else you missed.


 

ASTS NewsBrief
Colby Horton, Vice President of Publishing, 469.420.2601
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Esther Cho, Content Editor, 469.420.2671   
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