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Not too early to mark your calendars
Florida Society of Pathologists
41st Annual Anatomic Pathology Conference

Feb. 13-15, 2015
Disney's Contemporary® Resort
Lake Buena Vista, Orlando, Florida

Renowned Faculty Presenting Leading Edge Topics
Make your hotel reservation today! Enjoy Valentine's Day and President's Day Weekend with your family in Walt Disney World Call Disney's Group Reservations at 407-824-1383, option 1 and ask for FSP's discounted group rate. Detailed information on this sensational program and registration information will be posted to www.flpath.org.

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To find patients at highest risk, hospitals combine consumer data with clinical information
Dark Daily
Big data is all the rage in healthcare these days. However, one interesting development in this field is how hospitals are integrating consumer data with clinical data to identify patients at high risk. For example, if the post-surgical heart patient buys a package of cigarettes, some hospitals say they want to know. This is a trend with interesting implications for clinical laboratories.
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Risk to patients balanced against risk to labs as FDA moves on lab developed tests
Clinical Informatics News
In the nearly 40 years that laboratory developed tests have enjoyed a policy of "enforcement discretion," they have grown from a small but vital niche used mainly by hospital labs to diagnose rare diseases, to an industry where big players like Myriad Genetics and Genomic Health can post profits in the hundreds of millions of dollars.
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Open Payments website launches
Modern Healthcare
The federal government today launched a highly anticipated website detailing at least $3.5 billion in financial ties in a five-month period between medical device and drug companies and physicians and teaching hospitals. The Open Payments website is the first public repository of national data describing financial relationships between industry and healthcare providers. Critics of these payments say these payments can inappropriately influence clinical decisions.
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Mandatory extended RAS testing for mCRC
Medscape
Multiple subgroup analyses of randomized trials have suggested that patients who have "extended RAS" mutations (in exons 3 and 4 of KRAS and exons 2, 3, and 4 of NRAS) not only may not benefit from anti-epidermal growth factor receptor (EGFR) therapy but may potentially be harmed. Sorich MJ, Wiese, M.D., and colleagues conducted a systematic review and meta-analysis of such reported trials. Overall, nine trials of 5948 participants evaluated for both KRAS exon 2 and new RAS mutations met the inclusion criteria.
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Graphene sensor tracks down cancer biomarkers
Science 2.0
An ultrasensitive biosensor made from the wonder material graphene has been used to detect molecules that indicate an increased risk of developing cancer. The biosensor has been shown to be more than five times more sensitive than bioassay tests currently in use, and was able to provide results in a matter of minutes, opening up the possibility of a rapid, point-of-care diagnostic tool for patients.
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Prescription for the angry patient: Communication
The Huffington Post
Anger is the human response to unmet needs or expectations. When patients enter a hospital, they expect good care and good communication, and they usually expect to leave the hospital in better shape than they were in when admitted. Unfortunately, any deviance in meeting needs or expectations can result in anger. To complicate things, healthcare providers typically add to this anger by failing to communicate with the patient regarding why expectations were not met. Providers literally throw fuel on the fire by failing to communicate.
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Cancer genome sequencing will mean more targeted therapies
Forbes
As the cost of DNA sequencing plummets, the possibility of testing all cancer patients' tumor genomes is becoming a reality. For just $1000 or so, a doctor might submit most any malignant specimen for a complete genetic work-up. The sample might be a core needle biopsy taken from a breast, a blood sample from a person with leukemia, or a snippet of a sarcoma removed in an operating room. In principle, checking a tumor for genetic changes should be straightforward, do-able. But most cancer patients undergo surgery and other treatment long before their doctors consider sending a biopsy for full molecular evaluation.
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FSP has no control over and does not officially endorse the content of the information available on the links contained in the "Florida Pathology Today" or links imbedded in articles within the "Florida Pathology Today." These links are provided as a courtesy only. Linked sites are not a part of the "Florida Pathology Today." The owners of those linked sites, and not FSP, own the intellectual property rights to the material on the linked sites. FSP cannot certify the accuracy of material published on linked sites. Additionally, the contents of this e-Newsletter and the above referenced links, including any advice, suggestions, and/or recommendations have NOT been generated as part of any professional evaluation.

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Under no circumstances will the authors, editors, webmasters, and the FSP Board of Directors affiliated with the "Florida Pathology Today" be liable to you or anyone else for any decision made or any action taken by you or anyone else in reliance on such information or view, or for any incidental, consequential, special, or similar damages even if advised of the possibility of such damages.

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