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Welcome to the ICBS Discovery e-NewsBrief from the International Chemical Biology Society. This is a free, bi-weekly digest of headlines and news related to the chemical biology field. With a variety of stories selected from media outlets around the world, we hope you will find this publication informative. The e-NewsBrief will arrive in your email inbox every other Thursday.
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New therapeutic strategy discovered for ovarian cancer
Researchers have identified a new therapeutic target in a particularly aggressive form of ovarian cancer, paving the way for what could be the first effective targeted therapy of its kind for the disease. The findings were published online by the journal Nature Medicine.
Gold nanotubes launch a three-pronged attack on cancer cells
Scientists have shown that gold nanotubes have many applications in fighting cancer: internal nanoprobes for high-resolution imaging, drug delivery vehicles and agents for destroying cancer cells. The study, published in Advanced Functional Materials, details the first successful demonstration of the biomedical use of gold nanotubes in a mouse model of human cancer.
X-ray machine opens new frontier
Researchers in Palo Alto, California, have developed the most powerful X-ray laser in the world. The Linac Coherent Light Source is being used to see how atoms and molecules move in living systems. The machine is a billion times more intense than the previous generation of lasers. Each X-ray pulse has as much power as the national grid of a large country, and 100 are produced every second.
Artificial proteins could bring the next biological revolution
Scientists and engineers have looked to nature for their inspiration for centuries. The field of biomimetics uses ideas from nature to solve complex human challenges. Synthetic biology, a more recent concept, focuses on the design of artificial devices or systems with biological or "bio-like" functions. This covers a wide range of applications — but perhaps the most fascinating biological "device" we could wish to emulate is the protein.
Revolutionary new probe zooms in on cancer cells
Brain cancer patients may live longer thanks to a new cancer detection method developed by researchers. The collaborative team has created a powerful new intraoperative probe for detecting cancer cells. The handheld Raman spectroscopy probe enables surgeons, for the first time, to accurately detect virtually all invasive brain cancer cells in real time during surgery. The probe is superior to existing technology and could set a new standard for successful brain cancer surgery.
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Chemical biology: How to minimize antibodies
The success of antibodies as pharmaceuticals has triggered interest in crafting much smaller mimics. A crucial step forward has been taken with the chemical synthesis of small molecules that recruit immune cells to attack cancer cells.
New drug development to focus on genetics of cervical cancer
Drug Discovery & Development
University of Huddersfield researcher Dr. Tsitsi Chituku is taking part in a project that seeks to learn more about the genetic factors that make some women more susceptible to cervical cancer. It was a recent visit to Africa, to carry out a health screening project involving hundreds of women, which helped to shape the emphasis of her research.
More infectious diseases emerging because of climate change
The appearance of infectious diseases in new places and new hosts is a predictable result of climate change. Climate change brings humans, crops, wildlife and livestock into contact with new pathogens, which are more likely to jump from one host to another than scientists previously believed.
Breast cancer: 2 new genetic risk factors uncovered
Medical News Today
Collaboration between dozens of worldwide cancer research institutes has added to the ever-improving understanding of breast cancer genetics and personal profiling of the disease by unearthing two new genetic variants associated with a higher risk for the women carrying them. The two genetic susceptibility biomarkers identified by the huge study are specific to a type of hormone-dependent breast cancer — estrogen receptor-positive breast cancer, the most common form.
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