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Welcome to the ICBS Discovery e-NewsBrief from the International Chemical Biology Society. This is a free, bi-weekly digest of headlines and news related to the chemical biology field. With a variety of stories selected from media outlets around the world, we hope you will find this publication informative. The e-NewsBrief will arrive in your email inbox every other Thursday.
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Researchers identify more than 80 new genes linked to schizophrenia
Medical News Today
What causes schizophrenia has long baffled scientists. But in what is deemed the largest ever molecular genetic study of schizophrenia, a team of international researchers has pinpointed 108 genes linked to the condition — 83 of which are newly discovered — that may help identify its causes and pave the way for new treatments.
Shorter treatment for tuberculosis works in HIV patients
A three-drug combo that includes an experimental treatment from the Global Alliance for TB Drug Development may cure tuberculosis more quickly than current regimens, a study found, offering new hope to patients with HIV. At least one-third of 35 million people with HIV worldwide have latent TB, and they're 30 times more likely to develop the active disease.
Researchers show the danger of dormant viruses in the body
By Dorothy L. Tengler
Sepsis is caused by many different types of microbes, including bacteria, fungi and viruses. This is a major challenge in the intensive care unit of hospitals, where it is one of the leading causes of death. Every year, severe sepsis strikes about 750,000 Americans. It's been estimated that between 28 percent and 50 percent of these people die — far more than the number of deaths in the United States from prostate cancer, breast cancer and AIDS combined. Now, a provocative new study links prolonged episodes of sepsis to the reactivation of otherwise dormant viruses in the body.
Neuroprotective role of immune cell discovered
A type of immune cell widely believed to exacerbate chronic adult brain diseases, such as Alzheimer's disease and multiple sclerosis, can actually protect the brain from traumatic brain injury and may slow the progression of neurodegenerative diseases, according to research. "Our findings suggest the innate immune system helps protect the brain after injury or during chronic disease, and this role should be further studied," the lead researcher said.
Enhanced NIST instrument enables high-speed chemical imaging of tissues
A research team has demonstrated a dramatically improved technique for analyzing biological cells and tissues based on characteristic molecular vibration "signatures." The new NIST technique is an advanced form of the widely used spontaneous Raman spectroscopy, but one that delivers signals that are 10,000 times stronger than obtained from spontaneous Raman scattering.
New report details efforts to combat neglected tropical diseases worldwide
Vaccine News Daily
A new report from the Global Network identifies methods used by different countries to combat neglected tropical diseases that affect more than 1 billion of the world’'s poorest people. The report details efforts in Burundi, India and Mexico to eliminate some of the 17 diseases identified as NTDs, including schistosomiasis, onchocerciasis, intestinal worms, trachoma, leishmaniasis and Chagas disease.
Potential new flu drugs target immune response, not virus
The seriousness of disease often results from the strength of immune response, rather than with the virus itself. Turning down that response, rather than attacking the virus, might be a better way to reduce that severity, says Juliet Morrison of the University of Washington, Seattle. She and her collaborators have now taken the first step in doing just that for the H7N9 influenza.
Scientists discover new way to make human platelets
Scientists report they have discovered a new way to make fully functional human platelets. Using human stem cells and a device called a bioreactor, which mimics the body's natural way of producing blood cells but on a larger scale, the researchers said their method eliminates risks and complications associated with donor blood transfusion.
New combination drug controls tumor growth, metastasis in mice
A combination drug has been developed that controls both tumor growth and metastasis, a mouse study has shown. By combining a COX-2 inhibitor, similar to Celebrex, and an epoxide hydrolase inhibitor, the drug controls angiogenesis, limiting a tumor's ability to grow and spread.
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