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Text Version   RSS   Unsubscribe   Archive   Media Kit                     August 07, 2014

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Welcome to the ICBS Discovery e-NewsBrief from the International Chemical Biology Society. This is a free, bi-weekly digest of headlines and news related to the chemical biology field. With a variety of stories selected from media outlets around the world, we hope you will find this publication informative. The e-NewsBrief will arrive in your email inbox every other Thursday.

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Mining bacterial blueprints yields novel process for creation of fuel and chemical compounds
Phys.org
A team of researchers at the University of Wisconsin-Madison has identified the genes and enzymes that create a promising compound — the 19 carbon furan — containing fatty acid (19Fu-FA). The compound has a variety of potential uses as a biological alternative for compounds currently derived from fossil fuels.
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Seamless gene correction of beta-thalassemia mutations in patient-specific cells
Medical Xpress
A major hurdle in gene therapy is the efficient integration of a corrected gene into a patient's genome without mutating off-target sites. In a paper published recently in Genome Research, scientists have used CRISPR/Cas genome editing technology to seamlessly and efficiently correct disease-causing mutations in cells from patients with β-thalassemia.
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Repurposing a drug for abdominal cancer
ScienceDaily
A repurposed drug originally used to treat ovarian cancer saw positive results for patients with advanced peritoneal cancers during a phase I clinical trial, researchers report. The drug, known under the brand name Nanotax, is a fine particle reformulation of paclitaxel, the standard treatment for ovarian cancer.
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Scientists find 6 new genetic risk factors for Parkinson's
Neuroscience News
Using data from over 18,000 patients, scientists have identified more than two dozen genetic risk factors involved in Parkinson's disease, including six that had not been previously reported. The study, published in Nature Genetics, was partially funded by the National Institutes of Health and led by scientists working in NIH laboratories.
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Advance in capturing elusive circulating tumor cells
Bioscience Technology
When cancers spread into the bloodstream, they often take on different characteristics, requiring different therapies. But it is hard to find these rare blood-borne cells. So relapsed patients often do not get personalized care. Massachusetts General Hospital has come up with a solution that is exciting many oncologists.
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Model of viral lifecycle could help in finding a cure for hepatitis B
ScienceDaily
A new technique sustains hepatitis B in liver cells, researchers have discovered, allowing for the study of immune response and drug treatments. Around 400 million people worldwide are infected with the hepatitis B virus; of those, one-third will go on to develop life-threatening complications, such as cirrhosis and liver cancer.
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Advanced thin-film technique could deliver long-lasting medication
R&D Magazine
About 1 in 4 older adults suffers from chronic pain. Many of those people take medication, usually as pills. But this is not an ideal way of treating pain: Patients must take medicine frequently, and can suffer side effects, since the contents of pills spread through the bloodstream to the whole body.
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Small DNA modifications predict brain's threat response
Medical Xpress
The tiny addition of a chemical mark atop a gene that is well known for its involvement in clinical depression and posttraumatic stress disorder can affect the way a person's brain responds to threats, according to a new study by Duke University researchers.
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ICBS Discovery
Colby Horton, Vice President of Publishing, 469.420.2601
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