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Text Version   RSS   Unsubscribe   Archive   Media Kit                     December 11, 2014

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Welcome to the ICBS Discovery e-NewsBrief from the International Chemical Biology Society. This is a free, bi-weekly digest of headlines and news related to the chemical biology field. With a variety of stories selected from media outlets around the world, we hope you will find this publication informative. The e-NewsBrief will arrive in your email inbox every other Thursday.

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A yardstick to measure the malignancy of prostate cancer
Health Canal
The detection of this biomarker may serve as an indicator of the likelihood that the disease may take an aggressive course, and may thus be helpful in choosing an appropriate treatment. The study was part of the "Early Onset Prostate Cancer" project, supported by the Federal Ministry of Education and Research as part of the International Cancer Genome Consortium.
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Nanotechnology against malaria parasites
Science Daily
Malaria parasites invade human red blood cells, they then disrupt them and infect others. Researchers have now developed so-called nanomimics of host cell membranes that trick the parasites. This could lead to novel treatment and vaccination strategies in the fight against malaria and other infectious diseases.
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Injectable 3-D vaccines could fight cancer, infectious diseases
R&D Magazine
One of the reasons cancer is so deadly is that it can evade attack from the body's immune system, which allows tumors to flourish and spread. Scientists can try to induce the immune system to go into attack mode to fight cancer and to build long lasting immune resistance to cancer cells. Now, researchers show a non–surgical injection of programmable biomaterial that spontaneously assembles in vivo into a 3-D structure could fight and even help prevent cancer and also infectious disease such as HIV.
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Study points to new therapeutic strategy for chronic kidney disease
Nephrology News and Issues
A team led by researchers at the Perelman School of Medicine at the University of Pennsylvania has discovered an aspect of chronic kidney disease's development that points to a promising new therapeutic strategy. In the study, published online in advance of the print edition of Nature Medicine, researchers focused on a central feature of CKD: the "fibrosis" process.
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Painkiller tramadol linked to low blood sugar
HealthDay News
The narcotic painkiller tramadol (Ultram) seems to be associated with an increased risk of dangerously low blood sugar, Canadian researchers report. Tramadol is a narcotic drug whose use has increased steadily worldwide. The new research links taking the drug to around a threefold increased risk of being hospitalized for low blood sugar (hypoglycemia), according to the study.
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Nearing an obesity pill? Potential drugs make 'bad' fat 'good'
Genetic Engineering & Biotechnology News
Obesity continues to rise despite the abundance of diets, exercise regimens and even surgical interventions. Another obesity-suppressing possibility is anti-obesity pharmacotherapy, which has started to show promise after languishing for years. Especially encouraging are experiments showing that obesity can be curtailed by increasing the number or activity of brown-like adipocytes in white fat deposits.
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Novel drug target may lead to better treatment for schizophrenia
Medical Xpress
Scientists have identified a novel drug target that could lead to the development of better antipsychotic medications. Current treatment for patients with schizophrenia involves taking medications that block or interfere with the action of the neurotransmitter dopamine, which acts on dopamine D2 receptors in the brain. However, because it may cause unwanted side effects such as slow gait, stiffness and tremor, the researchers looked for new ways to interfere with the action of D2 receptors.
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Chemists create 'artificial chemical evolution' for the 1st time
Phys.Org
Scientists have taken an important step toward the possibility of creating synthetic life with the development of a form of artificial evolution in a simple chemistry set without DNA. A team from the University of Glasgow's School of Chemistry report in a new paper in the journal Nature Communications on how they have managed to create an evolving chemical system for the first time.
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