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Study redefines role of estrogen in cervical cancer
Medical Xpress
Scientists have prior evidence that the hormone estrogen is a major driver in the growth of cervical cancer, but a new study examining genetic profiles of 128 clinical cases reached a surprising conclusion: Estrogen receptors all but vanish in cervical cancer tumors. This counterintuitive finding, reported in the online Proceedings of the National Academy of Sciences, further bolsters the understanding of cervical cancer's progression and offers valuable new targets to fight the disease.
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SGO NEWS


Host or sponsor HPV documentary
A new documentary, “Someone You Love: The HPV Epidemic,” demonstrates the human toll of HPV infection and encourages the prevention of cervical and other HPV-related cancers through vaccinations and screening. SGO members may host or sponsor public screenings through their institutions. Register to preview the film here. Additional details on hosting and sponsoring are available here.
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VULVAR CANCER


Impact of adjuvant chemotherapy with radiation for node-positive vulvar cancer: A National Cancer Data Base (NCDB) analysis
Gynecologic Oncology
For node-positive vulvar cancer, adjuvant radiotherapy has an established benefit, whereas the impact of chemotherapy is unknown. A National Cancer Data Base (NCDB) analysis was conducted to determine patterns of care and evaluate the survival impact of adjuvant chemotherapy. In a large population-based analysis, adjuvant chemotherapy resulted in a significant reduction in mortality risk for node-positive vulvar cancer patients who received adjuvant radiotherapy.
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CERVICAL CANCER


College kids don't understand the HPV threat
U.S. News & World Report
Researchers surveyed 192 female undergraduate students at Oakland University in Michigan. The results showed that most of the respondents knew about the HPV vaccine, but 54 percent were not vaccinated. The findings were presented this week at the annual meeting of the American Society for Microbiology, in New Orleans.
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BREAST CANCER


IARC: Mammography still best for breast cancer screening, experts find
Medical News Today
The conclusions of the group, convened by the International Agency for Research on Cancer (IARC), are published in the New England Journal of Medicine and come following new data on screening practices and their outcomes. "Careful consideration of both the benefits and harms of mammography screening shows a net benefit from inviting women 50-69 years old," says Dr. Béatrice Lauby-Secretan, an IARC scientist. "The significant reduction in breast cancer mortality observed in this age group outweighs the effects of overdiagnosis and other adverse effects."
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CANCER INCIDENCE


Estimating the global burden of cancer in 2013; 14.9 million new cases worldwide
Science Daily
Researchers from around the world have worked together to try to measure the global burden of cancer and they estimate there were 14.9 million new cases of cancer, 8.2 million deaths and 196.3 million years of a healthy life lost in 2013, according to a Special Communication published online by JAMA Oncology. Cervical cancer ranked 10th, with 485,000 new cases and 236,000 deaths.
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GENETICS


NIPT IDs cancer in women prior to experiencing symptoms
GenomeWeb (Free login required)
Noninvasive prenatal testing for fetal chromosomal abnormalities can occasionally have the unexpected consequence of identifying malignancies in the expecting mom, according to a study published in JAMA Oncology that will also be presented at the European Society for Human Genetics meeting in London. Although rare, researchers at the University of Leuven in Belgium reported that out of 4,000 noninvasive prenatal tests ran in prospective pregnancies, three yielded aberrant genome representations that were confirmed to be maternal cancer (including one ovarian carcinoma).
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OBESITY


Obesity: Current and emerging drug treatments
The Pharmaceutical Journal
According to the World Health Organization, the prevalence of obesity has more than doubled worldwide since 1980; in 2014, more than 1.9 billion adults (39 percent of all people aged 18 years or older) were overweight, of whom more than 600 million were obese (13 percent of all adults). The majority of the world’s population live in countries where being overweight and obese causes more deaths than being underweight. Around 42 million children under the age of five years worldwide were overweight or obese in 2013. This article focuses on current and emerging drug treatments for people who are overweight or obese.
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Women's Cancer News
Colby Horton, Vice President of Publishing, 469.420.2601
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Jessica Taylor, Senior Medical Editor, 202-684-7169  
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