AVANIR Pharmaceuticals, Inc. is focused on commercializing novel therapeutic products.
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Brain cancer vaccine might turn fatal disease into a chronic condition
The Sacramento Bee
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When U.S. Sen. Edward Kennedy was diagnosed with a glioblastoma of the brain in May 2009, doctors understood there was little chance he could survive it. He died that August. "That's a malignant tumor. The current 5-year survival rate is 1 percent," says Ricardo Komotar, a neurooncologist at Sylvester Comprehensive Cancer Center. But cancer specialists from the University of Miami Medical School and nine other U.S. institutions are well into clinical experiments aimed at ending the tumor's fatal reputation.
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Stroke drug to get speedy FDA review
The Wall Street Journal
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In another victory for an anticlotting drug co-developed by Bristol-Myers Squibb Co. and Pfizer Inc., U.S. regulators agreed to a speedy review of the companies' application to market it. The U.S. Food and Drug Administration assigned "priority review" status to Eliquis, which Bristol and Pfizer propose to market for the prevention of strokes in people with a heart-rhythm disorder called atrial fibrillation. The targeted date for an FDA decision is March 28, 2012, sooner than some analysts had expected.
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Study: Bigger brains in certain types of autism
ABC News
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A new study adds to an increasing amount of evidence suggesting a link between brain size and autism. Researchers at the Mind Institute at the University of California at Davis have found that children with a certain type of autism, called regressive autism, generally have larger brains than children without the disorder, and for children with early onset autism.
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Hyperbaric oxygen treatment improves TBI and PTSD in veterans
MedIndia
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Treatment with hyperbaric oxygen benefits veterans with traumatic brain injury and post-traumatic stress disorder, say researchers. Sixteen U.S. veterans injured in Iraq who had been diagnosed with mild-moderate traumatic brain injury/post-concussion syndrome or traumatic brain injury/post-concussion syndrome/post-traumatic distress disorder were enrolled in the pilot study. They completed a history and physical exam as well as a clinical interview by a neuropsychologist, psychometric testing, symptom and quality of life questionnaires, and baseline SPECT brain blood flow imaging prior to treatment. The veterans then underwent 40 treatments of low-dose hyperbaric oxygen therapy during 60-minute sessions over a 30-day period.
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Brain images show abnormal areas in ADHD kids
PsychCentral
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In a small study, functional magnetic resonance imaging has identified abnormalities in the brains of children with attention deficit/hyperactivity disorder. Researchers believe the brain abnormalities may serve as a biomarker for the disorder.
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More evidence for environmental chemicals contributing to Parkinson's disease
Science a GoGo
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A new twin study has found a significant association between exposure to trichloroethylene and other chemicals used in dry cleaning, paints and cleaning products and the development of Parkinson's disease. Published in the Annals of Neurology, the study looked at a group of human twins where one twin had been exposed to TCE or other common solvent chemicals.
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Early behavior after head trauma predicts postconcussional syndrome
Clinical Psychiatry News
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Patients with mild traumatic brain injury who reported all or nothing behavior were significantly more likely to have postconcussional syndrome three months later, data from a prospective study of 107 adults have shown. Approximately 15-30 percent of mild traumatic brain injury patients are at risk of developing postconcussional syndrome. PCS is a symptom cluster that includes physical, cognitive, emotional and behavioral symptoms. To investigate the etiology of PCS, the researchers developed a cognitive-behavioral model that compared MTBI patients who did and did not develop the syndrome.
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New stent offering hope to people with inoperable brain aneurysms
Today's THV
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 An aneurysm is a weak spot on an artery wall that balloons into a bubble. If that bubble bursts, it may lead to serious brain damage or death. The design of a new stent makes it unique and it's giving patients, who otherwise aren't traditional candidates for surgery, another life saving option.
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Researchers identify proteins that ramp up ALS
Postmedia News via Montreal Gazette
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Despite decades of research, scientists have yet to identify the "silver bullet" to cure, or even slow, a lethal neurological disorder commonly called Lou Gherig's disease. But breakthrough research from Laval University in Quebec City has identified two proteins that conspire to promote amyotrophic lateral sclerosis. The finding brings new understanding — and hope for a therapeutic target — in a disease that appears without clearly associated risk factors in up to 95 percent of cases.
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