CoC Brief
Jul. 17, 2013

Largest cancer gene database made public
Reuters
National Cancer Institute scientists have released the largest-ever database of cancer-related genetic variations, providing researchers the most comprehensive way so far to figure out how to target treatments for the disease.More

Boosting immune therapy for cancer with nanoparticles
Phys.Org
Activating the body's immune system to attack cancer and prevent it from recurring is one of the Holy Grails of cancer research because of its ability to specifically target cancer and to search almost anywhere in the body for rogue tumors. More

Second cancer tied to first colon cancer site
Medpage Today
Colorectal cancer increased the risk of a secondary primary cancer as much as sevenfold, depending on the site of the original tumor, researchers found. Compared with the general population, previous colorectal cancer was significantly associated with a 15 percent increased risk of secondary cancer incidence (95 percent CI 1.13-1.16).More

The possible cancer toll of CT scans
The New York Times
Each year more than 4 million computed tomography scans are performed on children, and they are increasing the risk for future cancer, a new study suggests. Researchers writing online in June's JAMA Pediatrics counted the number of CT scans performed on children under 15 from 1996 to 2010 in seven American health care systems and calculated the average dose of radiation delivered to the head, abdomen, chest or spine.More

People with Alzheimer's are less likely to get cancer, and vice versa
The Washington Post
A new study suggests that people with Alzheimer's disease were 43 percent less likely to develop cancer and that people with cancer were 35 percent less likely to develop Alzheimer's disease, compared with the general population. The findings agree with those of earlier studies.More

DNA flaws may contribute to cancer risk in people with type 2 diabetes
Imperial College London
A type of genetic abnormality linked to cancer is more common in people with type 2 diabetes than the rest of the population, a new study has found. People with type 2 diabetes are already known to have a higher risk of cancers, especially blood cancers like lymphoma and leukaemia. More

Omega-3 fatty acids linked to higher risk of cancer
TIME via CNN
What's good for the heart may not be so healthy for other organs, says the latest study that links omega-3 fatty acids to an elevated risk of prostate cancer. It's not just an apple a day that keeps the doctor away anymore — recently, fish oils found in species like salmon, trout and tuna have been associated with a lower risk of heart disease and even Alzheimer's.More

Immunity proteins linked to cancer
Medical News Today
Researchers from a branch of the National Institute of Health have found a set of proteins involved in immunity — which is supposed to defend the body — that have the bad effect of creating a large number of mutations in DNA. These genetic mutations may be just as powerful as other known causes of cancer in producing tumors in the human body, the researchers say.More

Finding cancer cells in the blood
MIT Technology Review
In the near future, oncologists may be using a finger-size plastic chip with tiny channels to extract a dozen or so cancer cells from a sample of a patient's blood. Those cells, called circulating tumor cells, could then be screened for genetic disruptions that an oncologist could target with drugs best suited to attacking the tumor.More

AJCC calls for contributors to Cancer Staging Manual, 8th Edition
American Joint Committee on Cancer
The American Joint Committee on Cancer is seeking cancer professionals to collaborate on the development of the AJCC Cancer Staging Manual, 8th Edition.

A number of opportunities are available in two areas:

  • Disease Site Expert Panel: Members will research, write, review or otherwise contribute to chapter content.
  • Review Core: Members will provide expert review of all content in the areas of evidence-based medicine and statistics, precision medicine, cancer registry and surveillance and data harmonization.

    Access the application online. AJCC will not accept unsolicited curriculum vitaes. Only individuals who complete this application will be considered. The application period will close July 31. Contact ajcc@facs.org for more information.More