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Aspirin's ability to prevent colon cancer may depend on your genes
HealthDay News via U.S. News & Health Report
Aspirin seems to halve the risk of colon cancer in people with high levels of a genetic enzyme found in the colon, a new study says. Many questions remain, however, regarding who should take aspirin to potentially ward off colon cancer. The research isn't definitive, there's no easy test for patients to take to assess potential benefits, and aspirin can cause serious side effects.
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Y chromosome loss:Shorter life expectancy and higher cancer risk men
Medical News Today
Compared with women, men have a shorter life expectancy. The U.S. Centers for Disease Control and Prevention estimate that women live an average of five years longer than men. Now, a new study suggests this disparity may be down to a loss of the Y chromosome in blood cells, prompting men to have a shorter life span and higher mortality from cancer. The researchers published the results of their latest findings in the journal Nature Genetics.
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Version 3 of the CP³R now available
ACS
The latest version of the Cancer Program Practice Profile Reports (CP³R) has been posted with the following features:
  • Data are displayed for diagnosis years 2009, 2010, and 2011.
  • Three new breast measures have been added (see more information at http://www.facs.org/cancer/qualitymeasures.html).
  • Registrars can edit codes that affect whether or not the case belongs in the denominator of the measures, replacing the function of the former "censor" button.
  • Navigation is simplified, and both facility and comparison performance rates update when changes are made.
  • Documentation is improved (see http://www.facs.org/cancer/ncdb/cp3r.html).

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Noninvasive tumor burden screening
Oncology Nurse Advisor
An ultrasensitive method measures circulating tumor DNA (ctDNA), which allows ctDNA to be used as a noninvasive biomarker to quantify cancer burden in patients. This method is more useful than existing techniques, as it is less expensive, provides high sensitivity, and can be used for patients with various different tumor genotypes, as long as recurrent mutation data is known for their tumor type. Previously reported methods for next-generation sequencing (NGS) have been limited by their modest sensitivity, ability to apply only to a minority of patients, the need to be optimized specifically for each patient, and the cost of that optimization.
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Register now for the 2014 CoC workshop — Strengthening Your Cancer Program...Enriching the Coordinators' Role
Commission on Cancer
On June 19-20 in Chicago, the Commission on Cancer (CoC) will hold a new workshop entitled Strengthening Your Cancer Program…Enriching the Coordinators' Role. This program provides information and case studies on the roles and responsibilities of the various CoC-designated coordinators. The two-day program will cover what the various coordinators' roles are, what their roles on the cancer committee involve, and how to meet and improve the required responsibilities based on the CoC Standards. Register for the program. Program fees are $650 if registration is received on or before May 15 and $750 if registration is received after May 15.
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From an apple a day to 'energy balance' in cancer research
The New York Times
In his recent Raw Data column about whether fruits and vegetables are crucial to avoiding cancer, George Johnson referred to two thick reports, published in 1997 and 2007 by the American Institute for Cancer Research and its affiliate, the World Cancer Research Fund. The books look similar: One cover is blue and the other green, and both are adorned with images of fruits, vegetables, legumes, and grains interspersed with people working and playing, all apparently enjoying good health. Presiding over the scene is an image of Mother Earth.
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Biomarker identifies melanoma patients who may respond to immunotherapy
Oncology Nurse Advisor
Among melanoma patients treated with PD-1 inhibitor MK-3475, those whose tumors had the protein PD-L1 had better immune responses and higher survival rates. These research results were presented at the American Association for Cancer Research 2014 Annual Meeting, in San Diego, Calif. When the protein PD-L1, which is present on some melanoma tumors, binds to PD-1, a protein present on T cells, brakes are applied to these T cells, preventing them from attacking the cancer cells. The immunotherapy MK-3475 blocks PD-1, releasing the brakes on T cells and enabling them to attack the cancer cells.
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Register now — Strengthening Your Cancer Program...Utilizing the Rapid Quality Reporting System to Comply with the New Commendation Standard
Commission on Cancer
Strengthening Your Cancer Program...Utilizing the Rapid Quality Reporting System to Comply with the New Commendation Standard will be held on June 18 in Chicago, the day before the 2014 CoC Workshop. This workshop will provide important information to help your program comply with the new commendation standard that requires programs, from initial enrollment and throughout the three-year accreditation period, to participate in the Rapid Quality Reporting System (RQRS). Register now for the program; registration fees are $250 if registration is received on or before May 15 and $300 if registration is received after May 15, 2014.
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More hospitals tailor cancer care to teens and young adults
The New York Times
New treatments and earlier detection have led to steady gains in cancer survival for children and adults. But survival rates for teens and young adults with some types of cancer have barely budged in 30 years. A push is on for better care and better outcomes for patients in what the National Cancer Institute calls a "no man's land" between pediatric and adult oncology. At present, adolescents and young adults may be treated in adult units or in children's wards — both places they are likely to feel isolated and distressed.
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BMI linked to breast cancer risk after menopause
Reuters
Overall body size, rather than shape, is a better indicator of breast cancer risk after menopause, according to a recent study. The analysis of U.S. women contradicts past research suggesting that having an apple shape with a large midriff measurement, regardless of weight or body mass index (BMI), might signal greater breast cancer risk. "When we looked at both BMI and waist size, we found that BMI explained the relationship (with breast cancer risk), and that the waist circumference had little effect," said Mia Gaudet, an American Cancer Society epidemiologist who led the new study.
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The Recovery Room Show — New episode available
ACS
You understand health, but do you understand medicine? Making sense of modern medicine, The Recovery Room, supported by the American College of Surgeons and hosted by Frederick L. Greene, MD, FACS, is an audio conversation with experts in surgery, medicine, ethics, and public health about the latest developments in medicine and health care. The latest episode, "Smoking Cessation and the Surgical Patient," is now available. It features Eric Skipper, MD, FACS, chief of adult cardiothoracic surgery at the Sanger Heart & Vascular Institute, Charlotte, N.C., and Michael Rosen, MD, FACS, professor of surgery and chief of GI and general surgery at Case Western Reserve University, Cleveland, Ohio.
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Advances in immunotherapy for the treatment of non-small cell lung cancer
OncLive
Lung cancer continues to be the leading cause of cancer-related deaths worldwide. Approximately 80 percent of lung cancers are diagnosed as non-small cell lung cancer (NSCLC), which is further classified into three main histologies: adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. The treatment decisions for NSCLC are primarily dependent on the patient’s performance status, extent of disease, and histological subtype.
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National Accreditation Program for Breast Centers presents the Pursuing Excellence through Accreditation Workshop
NAPBC
Plan now to attend the Pursuing Excellence through Accreditation Workshop May 23 in Chicago. Designed for centers seeking accreditation for the first time as well as centers due for re-accreditation, this program will increase your understanding of the National Accreditation Program for Breast Centers (NAPBC) accreditation process and help you prepare for the survey visit. Space is limited, so please make sure you register early.
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Disclaimer: The CoC Brief is a digest of the most important news selected for the American College of Surgeons Commission on Cancer from thousands of sources by the editors of MultiBriefs, an independent organization that also manages and sells advertising. The Commission on Cancer does not endorse any of the advertised products and services. Opinions expressed in the articles are those of the author and not of the American College of Surgeons and the Commission on Cancer.


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