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Study: In treating some cancer patients, less is more
Reuters
Doctors can scale back treatment for certain cancer patients, based on evidence that some drugs can be used less frequently, according to new information that is clearing the way for physicians to limit the risks of care. Several studies backing up this "less-is-more" strategy, which can also lower the cost of care, were presented at the American Society of Clinical Oncology meeting in Chicago.
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Combination treatment shows early promise for metastatic pancreatic ductal cancer
Oncology Nurse Advisor
A combination of several small doses of an investigational radioimmunotherapy and the chemotherapy gemcitabine had superior outcomes compared with radioimmunotherapy alone in patients with metastatic pancreatic ductal cancer, according to phase Ib clinical trial data presented at the American Association for Cancer Research special conference, Pancreatic Cancer: Innovations in Research and Treatment, in New Orleans, Louisiana.
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Register now — Strengthening Your Cancer Program...Utilizing the Rapid Quality Reporting System to Comply with the New Commendation Standard
Commission on Cancer
Strengthening Your Cancer Program...Utilizing the Rapid Quality Reporting System to Comply with the New Commendation Standard will be held on June 18 in Chicago, the day before the 2014 CoC Workshop. This workshop will provide important information to help your program comply with the new commendation standard that requires programs, from initial enrollment and throughout the three-year accreditation period, to participate in the Rapid Quality Reporting System (RQRS). Register now for the program; registration fees are $250 if registration is received on or before May 15 and $300 if registration is received after May 15, 2014.
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25 percent of smokers carry newly discovered genetic link to lung cancer
Medical Daily
Smokers need to be aware of another cancer risk factor — a factor that happens to affect 25 percent of the smoking population. Researchers at The Institute of Cancer Research in London found a gene defect that increases risk noticeably. Their work was published in the journal Nature Genetics. After comparing the DNA of 11,348 Europeans with lung cancer and 15,861 cancer-free patients, researchers found a particularly strong contention for those with the squamous cell lung cancer type.
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    Coming soon — Learning the Basics of CoC Accreditation Workshop
    Commission on Cancer
    The first program, held early this year, was a sell-out. To meet the numerous requests, the Commission on Cancer (CoC) will repeat Learning the Basics of CoC Accreditation on September 12, 2014, in San Antonio, Texas. Plan now to attend the only program developed by the professionals who are involved in CoC standards development and the survey process. Watch your e-mail for detailed information or contact srubin@facs.org.
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    Reduced kidney function linked with higher risk of kidney and urothelial cancers
    Nephrology
    Reduced kidney function may increase the risk of developing kidney and urothelial cancers, according to a study appearing in the Journal of the American Society of Nephrology. The findings suggest that patients with kidney disease may benefit from more intensive screenings for these types of cancer. “While multiple studies have observed higher risks of cancer in persons with end-stage renal disease, the association of less severe kidney disease with cancer remains poorly understood,” said Alan Go, MD, from Kaiser Permanente Northern California.
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    Immune therapies improve treatment of cancers
    USA Today
    For more than a century, doctors have dreamed of using the body's own defenses to keep cancer in check, but most efforts either did nothing or over-revved the immune system, causing terrible side effects or even death. A half dozen experimental trials presented at the ongoing American Society of Clinical Oncology conference in Chicago, Illinois, show that researchers are finally making significant progress.
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    Register now for the 2014 CoC Workshop — Strengthening Your Cancer Program...Enriching the Coordinators' Role
    Commission on Cancer
    On June 19-20 in Chicago, Illinois, the Commission on Cancer (CoC) will hold a new workshop entitled Strengthening Your Cancer Program…Enriching the Coordinators' Role. This program provides information and case studies on the roles and responsibilities of the various CoC-designated coordinators. The two-day program will cover what the various coordinators' roles are, what their roles on the cancer committee involve, and how to meet and improve the required responsibilities based on the CoC Standards. Register for the program. Program fees are $650 if registration is received on or before May 15 and $750 if registration is received after May 15.
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    Study: Early chemo may help men with prostate cancer live longer
    TIME
    Men diagnosed with prostate cancer will often put off chemotherapy with their doctor’s approval. But new research suggests that men who get chemotherapy early on may actually live longer. Typically, men with prostate cancer will start their treatment with active surveillance of their tumors before starting hormone therapy. Men will undergo chemotherapy only when their tumors become resistant to hormone therapy. But a recent clinical trial found that men treated early with chemotherapy lived longer than men who underwent the standard treatment.
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    Chemotherapy following radiation treatment improves progression-free survival
    Medical Xpress
    A chemotherapy regimen consisting of procarbazine, CCNU, and vincristine (PCV) administered following radiation therapy improved progression-free survival and overall survival in adults with low-grade gliomas, a form of brain cancer, when compared with radiation therapy alone. The findings were part of the results of a Phase III clinical trial presented at the 2014 American Society of Clinical Oncology Annual Meeting by the study's primary author Jan Buckner, MD, deputy director, Cancer Practice, at Mayo Clinic Cancer Center.
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    FORDS revision project
    Commission on Cancer, National Cancer Data Base
    FORDS is a manual that contains all of the data items with rules and coding options for cancer registrars to collect data in their hospital registry. These data are then submitted to the National Cancer Data Base (NCDB). The data available in the NCDB come from FORDS, Collaborative Stage, and the AJCC Cancer Staging Manual. The Commission on Cancer (CoC) is seeking input from registrars, data users, physicians, and others to modernize the current FORDS manual. This project kicked off in April 2014. The input will be gathered through an electronic survey, which will be open through September 2014.
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    New way to predict response to chemotherapy in triple-negative breast cancer
    Oncology Nurse Advisor
    The presence of tumor-infiltrating lymphocytes ahead of treatment may help predict response to platinum-based chemotherapy in women with triple-negative breast cancer, according to a new study. The data are being presented at the American Society for Clinical Oncology (ASCO) Annual Meeting in Chicago, Illinois. Triple-negative breast cancers are those that do not have estrogen or progesterone receptors and do not have an excess of the HER2 protein on the cancer cell surfaces. This makes it more difficult to treat because hormone-blocking or HER2-targeting treatments are not effective. Triple-negative breast cancers tend to occur more often in younger women and in African American women.
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    The CoC Brief

    Colby Horton, Vice President of Publishing, 469.420.2601
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    Samantha Emerson, Content Editor, 469.420.2669
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    Disclaimer: The CoC Brief is a digest of the most important news selected for the American College of Surgeons Commission on Cancer from thousands of sources by the editors of MultiBriefs, an independent organization that also manages and sells advertising. The Commission on Cancer does not endorse any of the advertised products and services. Opinions expressed in the articles are those of the author and not of the American College of Surgeons and the Commission on Cancer.


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