ASCLS eNewsBytes
Mar. 11, 2014

Gene-editing method tackles HIV in first clinical test
A clinical trial has shown that a gene-editing technique can be safe and effective in humans. For the first time, researchers used enzymes called zinc-finger nucleases to target and destroy a gene in the immune cells of 12 people with HIV, increasing their resistance to the virus. The findings are published in The New England Journal of Medicine.More

CLMA's KnowledgeLab 2014: Connect. Grow. Lead.
The Clinical Laboratory Management Association's premier educational event, KnowledgeLab 2014, May 4-7 in Las Vegas, provides a forum for laboratory leaders from all over the world to connect with their peers, grow their knowledge and lead the charge to address key challenges in the laboratory.

Register on or before March 28 to save up to $150!

Access the best in laboratory management training and information.

  • Daily general sessions featuring Michael Astion, M.D., Ph.D., Seattle Children's Hospital and Robert Michel, The Dark Report
  • Education covering essential topics
  • Pre-conference workshop presented by the Joint Commission on Tracer Methodology
  • The CLMA Leadership Curriculum — a deep dive into leadership skill development for those who are new to the management role and for current leaders who wish to enhance their proficiency

  • Register for KnowledgeLab 2014 today and find new ideas and new approaches to implement in your own laboratory.

    Hear why you should attend KnowledgeLab 2014. Hear why Ellen Dijkman Dulkes, KnowledgeLab 2014 Program Committee Chair, thinks you should attend KnowledgeLab this May!More

    Medical Laboratory Professionals Week — April 20-26
    American Society for Clinical Laboratory Science
    It is time to celebrate and educate others about what YOU do! Start planning your celebration now. Purchase official logo items and more. For more information go to

    CDC: Hospitals contributing to rise of superbugs
    Health officials have long been warning us about the overuse of antibiotics and the rise of drug-resistant "superbugs." Now the Centers for Disease Control and Prevention is shining a light on how hospitals are contributing to the problem.More

    30,000-year-old giant virus 'comes back to life'
    BBC News
    An ancient virus has "come back to life" after lying dormant for at least 30,000 years, scientists say. It was found frozen in a deep layer of the Siberian permafrost, but after it thawed it became infectious once again. The French scientists say the contagion poses no danger to humans or animals, but other viruses could be unleashed as the ground becomes exposed.More

    The breast cancer racial gap
    The New York Times
    A troubling racial divide in breast cancer mortality continues to widen in most major cities around the country, suggesting that advances in diagnosis and treatment continue to bypass African-American women, according to new research. An analysis of breast cancer mortality trends in 41 of the largest cities in the United States shows that the chance of surviving breast cancer correlates strongly with the color of a woman's skin.More

    A complete medical checkup on a chip
    R&D Magazine
    About the size of a stapler, this new handheld device developed at EFPL in Switzerland is able to test a large number of proteins in our body all at once — a subtle combination of optical science and engineering.More

    Disease reporting volume may double with required electronic reporting
    Regenstrief Institute via Infection Control Today
    Public health departments nationwide are already feeling the strain from budget cuts. But their case report volumes are forecast to double when federal requirements for automated electronic laboratory reporting of notifiable diseases go into effect next year, according to a new study by researchers from the Regenstrief Institute Inc. and the Indiana University School of Informatics and Computing at Indiana University-Purdue University Indianapolis.More

    New contraceptive ring aims to protect against both pregnancy and HIV
    Fox News
    Researchers at Northwestern University have come up with a new option in prevention of unplanned pregnancies and the transmission of HIV: An intravaginal ring that helps prevent pregnancy while simultaneously releasing low doses of an antiretroviral drug that reduces a woman's risk of contracting both HIV and genital herpes.More

    Vitamin D may boost breast cancer survival odds
    CBS News
    Vitamin D may help women with breast cancer survive the disease. Researchers reported in a recent issue of Anticancer Research that patients with high levels of vitamin D in their blood were twice as likely to survive the disease than women with low levels of the nutrient.More

    Nuclear stiffness keeps stem cells and cancer cells in place
    Bioscience Technology
    Adult stem cells and cancer cells have many things in common, including an ability to migrate through tiny gaps in tissue. Both types of cells also experience a tradeoff when it comes to this ability; having a flexible nucleus makes migration easier but is worse at protecting the nucleus' DNA compared to a stiffer nucleus. Nuclear proteins that regulate nuclear stiffness are therefore thought to control processes as diverse as tissue repair and tumor growth.More

    Gene-editing method tackles HIV in first clinical test
    A clinical trial has shown that a gene-editing technique can be safe and effective in humans. For the first time, researchers used enzymes called zinc-finger nucleases to target and destroy a gene in the immune cells of 12 people with HIV, increasing their resistance to the virus. More

    Study: Vinegar a key to killing drug-resistant TB
    U.S. News & World Report
    One of the world's oldest known disinfectants — and favorite salad dressings — may prove even stronger than previously thought. An international research team has found that vinegar — or, more specifically, the active ingredient in vinegar — can kill mycobacteria, including a highly drug-resistant form of tuberculosis.More

    Mysterious polio-like illness affects kids in California
    USA Today
    A mysterious polio-like syndrome has affected as many as 25 California children, leaving them with paralyzed limbs and little hope of recovery. California is working with the Centers for Disease Control and Prevention in Atlanta to see if there are cases outside California. So far none have been reported.More

    Researchers claim blood test predicts Alzheimer's
    MedPage Today
    Blood biomarkers in cognitively normal seniors were associated with their 3-year risk of developing mild cognitive impairment or Alzheimer's disease, researchers said, although the accuracy fell short of what would normally be acceptable for a screening test. More

    Chemists discover new class of antibiotics
    Notre Dame University via Infection Control Today
    A team of University of Notre Dame researchers have discovered a new class of antibiotics to fight bacteria such as methicillin-resistant Staphylococcus aureus and other drug-resistant bacteria that threaten public health. The new class, called oxadiazoles, was discovered in silico (by computer) screening and has shown promise in the treatment of MRSA in mouse models of infection, according to research published in the Journal of the American Chemical Society. More