ASCLS eNewsBytes
Apr. 17, 2012

Experts predict explosive growth in molecular diagnostics and next-generation gene sequencing for clinical pathology laboratories
Dark Daily
Explosive rates of growth in clinical use of molecular diagnostics assays seen in recent years are about to be matched by a new opportunity for medical laboratory testing. Experts predict the coming "big thing" in clinical laboratory and anatomic pathology will be next-generation gene sequencing. This should be welcome news for financially-beleaguered pathology groups and clinical lab organizations. Lab tests that incorporate next-generation gene sequencing technologies are expected to offer clinicians greater value by making it possible to more accurately detect and characterize disease at earlier stages. More

FDA takes steps to protect public health
Lab Manager
The U.S. Food and Drug Administration announced that it is taking three steps to protect public health and promote the judicious use of medically important antibiotics in food-producing animals. Antimicrobial resistance occurs when bacteria or other microbes develop the ability to resist the effects of a drug. Once this occurs, a drug may no longer be as effective in treating various illnesses or infections.More

Hospital-acquired infections quadruple ICU mortality
Medscape Medical News
Elderly patients treated with central catheter and/or mechanical ventilation devices in intensive care units, admitted from the emergency department or as an urgent case, are at very high risk for hospital-acquired infection, according to the results of research presented at the 22nd European Congress of Clinical Microbiology and Infectious Diseases in London.More

Turning stem cells into a powerful weapon against AIDS
Researchers say the groundbreaking discovery they made at UCLA could one day potentially lead to a cure for Aids, Cancer, and other deadly viruses. They figured out how to engineer stem cells taken from adult blood, and turn them into immune cells that attack and kill the HIV virus. The history making breakthrough even surprised them.More

C. difficile infections at all-time high
Clinical Laboratory News
A new report released by the Centers for Disease Control and Prevention found that Clostridium difficile infections are on the rise in all types of healthcare settings, posing an increased threat to patient safety. The findings show that older adults who take antibiotics and also receive medical care in any setting are at the greatest risk.More

Yersinia pestis
ADVANCE for Medical Laboratory Professionals
The rapid identification of microorganisms is often of paramount importance in human health. One such organism when this is especially true is Yersinia pestis, the causative agent of plague. Earlier, confirmatory tests for the diagnosis of infection included the isolation and identification of bacterial colonies or the demonstration of a four-fold increase in antibody titers against its capsule antigenMore

Replication of immunodeficiency virus in humans
Medical Xpress
The AIDS pandemic is caused by the human immunodeficiency virus, which attacks the immune system and leaves infected individuals susceptible to opportunistic infections. AIDS and HIV-1 are thought to have a relatively short history in humans, with the first infections likely occurring around the turn of the 20th century.More

Urine is not sterile, PCR analysis shows
Medscape Medical News
The bladder holds a world of bacteria that do not show up in standard cultures, regardless of whether a woman has symptoms of a urinary tract infection, according to a study published online in the April print issue of the Journal of Clinical Microbiology.More

Aggressive prostate cancer risk linked with 2 genetic
deletions in human genome

Medical News Today
According to a study published online in Proceedings of the National Academy of Sciences, researchers have identified two inherited-genetic deletions in the human genome associated to the development of prostate cancer. The study reveals that men are three or four times more likely to develop the disease depending on the genetic variant they inherit.More

Huntington's linked to reduced cancer risk
Medscape Medical News
Patients with Huntington's disease or other polyglutamine diseases appear to have a reduced risk for development of cancer, results of a Swedish population-based study suggest. Researchers found a significantly and consistently reduced incidence of cancer overall and of cancers of specific sites and types in patients with HD, spinobulbar muscular atrophy, or hereditary ataxia, relative to the general population of Sweden.More

Blood type A may predispose to some rotavirus infections
Infection Control Today
Whether you become infected by some strains of rotavirus may depend on your blood type. Some strains of rotavirus find their way into the cells of the gastrointestinal tract by recognizing antigens associated with the type A blood group, a finding that represents a new paradigm in understanding how this gut pathogen infects humans, said Baylor College of Medicine researchers in an online report in the journal Nature. Rotavirus is a major intestinal pathogen that is the leading cause of severe dehydration and diarrhea in infants around the world. An estimated 500,000 people worldwide die from the infection annually. More

Clinical pathology laboratories beef up courier and logistics services to deliver more value to client physicians
Dark Daily
Medical laboratories gain competitive advantage by using GPS and real-time vehicle tracking to improve performance of their couriers Like everything else in laboratory medicine, even such once-simple operational areas as logistics and courier services are becoming complicated — and more expensive. The reasons are familiar to all clinical laboratory managers and pathologists. More