ASCLS eNewsBytes
Apr. 28, 2015

Gene-editing technique offers hope for hereditary diseases
Salk Institute for Biological Studies via ScienceDaily
Scientists have used molecular "scissors" to eliminate mitochondrial mutations in eggs and embryos. They are now investigating the possibility of translating this technology to the clinic in human eggs and embryos.More

Researchers regenerate heart cells in mice
By Lynn Hetzler
Myocardial infarction, or MI, causes irreversible necrosis of heart muscle secondary to prolonged ischemia. Scar tissue begins to build almost immediately, leading to the loss of contractile myocardium, which is a frequent cause of chronic heart failure. However, a new study suggests there may someday be a way to stimulate the body into regenerating heart cells after MI. The research results, published in Nature Cell Biology, may eventually help clinicians reduce cardiomyopathy and stimulate cell regeneration in heart attack patients.More

Study: Ebola outbreak may have led to almost 11,000 more malaria deaths
HealthDay News via U.S. News & World Report
Nearly 11,000 extra deaths due to malaria may have occurred in 2014 because of disruptions in health care services caused by the Ebola outbreak in West Africa, a new study suggests. Another 3,900 extra malaria deaths may have been caused by the interruption of delivery of insecticide-treated sleeping nets, the British researchers said.More

CDC issues update on H5 viruses in the US
Cenetrs for Diseae Control and Prevention via Infection Control Today
Highly pathogenic avian influenza H5 infections have been reported in U.S. domestic poultry, captive wild birds and wild birds. HPAI H5 detections began in December 2014 and have continued into April 2015.More

Study: Breast cancer cases estimated to increase 50 percent by 2030
The Huffington Post
Breast cancer diagnoses in the U.S. will grow by as much as 50 percent by 2030, according to a new analysis by researchers at the National Cancer Institute, part of the National Institutes of Health. The increase in cancer cases can be attributed to the aging of female baby boomers, a population of about 40 million American women born between 1946 and 1964 who also happen to be living longer, according to the researchers.More

Coffee 'could halve breast cancer recurrence' in tamoxifen-treated patients
Medical News Today
A new study led by researchers from Lund University in Sweden claims women diagnosed with breast cancer who are taking the drug tamoxifen could halve their risk of recurrence by drinking coffee. The findings build on those from a previous study conducted by Lund University researchers in 2013, in which the team found a link between coffee consumption and reduced breast cancer recurrence in 300 women who used tamoxifen.More

Solutions to the problems of rural hospitals must address the need for adequate clinical laboratory and anatomic pathology testing services
DARK Daily
Times are tough for rural hospitals, and officials in many states are looking at new models for health care delivery in rural areas. Anatomic pathology groups with contracts to serve rural hospitals will be affected by any changes in how rural hospitals are funded and operated. One suggested approach to replace the existing community hospital model for rural area is called a hybrid model. More

HPV screening alone may miss cervical cancer
Medscape
Human papillomavirus screening used on its own can miss cervical cancer, according to a study that found that more cases were detected when it was used in combination with cytology. The study was published online April 10 in Cancer Cytopathology.More

Antibiotic shortages on the rise in US
HealthDay News
Shortages of antibiotics, including those used to treat drug-resistant infections, may be putting patients at risk for sickness and death, according to a new report. Between 2001 and 2013, there were shortages of 148 antibiotics. And the shortages started getting worse in 2007, researchers found.More

Faster, smaller, cheaper: Technique could speed biologic drugs
Lab Manager
Antibodies are specific molecules that can lock onto a particular cellular structure to start, stop or otherwise temper a biological process. Because they are so specific, antibodies are at the forefront of drug discovery. So drug companies want a faster route to step one: identifying which of the millions of possible antibodies will work against molecules that cause disease.More