ASCLS eNewsBytes
May. 7, 2013

Cancers share gene patterns, studies affirm
The New York Times
Scientists have discovered that the most dangerous cancer of the uterine lining closely resembles the worst ovarian and breast cancers, providing the most telling evidence yet that cancer will increasingly be seen as a disease defined primarily by its genetic fingerprint rather than just by the organ where it originated.More

Researchers announce point-of-care device that detects microRNA in 20 minutes
Dark Daily
Pathologists will be interested to learn that Japanese researchers have developed a second-generation lab-on-a-chip that detects microRNA from a tiny sample volume in only 20 minutes! Their goal is to create a point-of-care device for early detection of cancer. More

Malignancy less likely in incidentally discovered thyroid nodules
Medscape Medical News
Thyroid nodules found on clinical examination were much more likely to be malignant than were those seen incidentally during imaging studies for other reasons, according to a new review of 200 consecutive patients referred to a thyroid center. The findings, which differ from those previously reported in the literature, were presented at the American Association of Clinical Endocrinologists 22nd Annual Scientific and Clinical Congress by Robert A. Levine, M.D., and Jessica K. Levine.More

Important microscopic technique advanced for biomedical research
TU Delft via R&D Magazine
Scientists at TU Delft have made an important advancement in a new microscopic technique that is widely used in medical research. They demonstrate what the resolution of this localization microscopy is and how the best resolution can be achieved as quickly as possible. Their findings are published online in Nature Methods.More

Lab, hospitals collaborate on new cancer treatment
Hartford Courant
Connecticut cancer patients will participate in a clinical trial in which researchers extract tumor cells, graft them onto mice, and then use the mice as patient avatars so scientists can develop treatment tailored to the individual.More

Collaborative research network aims to understand spread of diseases
The Medical News
The Models of Infectious Disease Agent Study is a collaborative research network funded by the National Institutes of Health that uses computational, statistical and mathematical models to understand the spread of infectious diseases such as influenza, pertussis, West Nile disease, dengue fever and cholera. Since its inception nearly 10 years ago, MIDAS has pioneered the use of computational and mathematical models to prepare for, detect and respond to infectious disease threats.More

Tiny Faroe Islands to begin sequencing genomes of all 50,000 residents
Dark Daily
Because of the dramatic — and still falling — cost of DNA sequencing, an ambitious project is launching with the goal of sequencing the full DNA of all 50,000 residents of the Faroe Islands. When completed, this project has the potential to reshape molecular diagnostics and clinical laboratory testing.More

Bills require VA report infectious diseases to states
Pittsburgh Post-Gazette
The Legionnaires' disease outbreak at Pittsburgh Veterans' Affairs' facilities continues to spur action from Congress. A U.S. House bill introduced recently would require all VA medical facilities nationwide to report patients' cases of infectious diseases to state health departments where they're located, a requirement by which nonfederal hospitals have to abide, but from which VA facilities are exempt.More

Federal panel: Everyone 15 to 65 should have HIV test
Los Angeles Times
Citing recent evidence that HIV infections are best managed when treated early, an influential panel of medical experts has finalized its recommendation that all people ages 15 to 65 be screened for the virus that causes AIDS. The recommendation from the U.S. Preventive Services Task Force seeks to address one of the key challenges in the fight against HIV/AIDS: The window during which patients respond best to treatment is also the time when symptoms of the disease are least noticeable.More

Tests on cancer cells shows them as 'squishy,' yet tactically strong
R&D Magazine
A team of student researchers and their professors from 20 laboratories around the country have gotten a new view of cancer cells. The work could shed light on the transforming physical properties of these cells as they metastasize, said Jack R. Staunton, a Ph.D. candidate at Arizona State University in the lab of professor Robert Ros, and the lead author of a paper reporting on the topic. More

Broad MRSA screening in UK not cost-effective
Medscape Medical News
The current methicillin-resistant Staphylococcus aureus screening policy in place at the National Health Service in the United Kingdom is not cost effective, new research suggests. More

Study finds no fertility drugs, ovarian cancer link
Reuters
Despite lingering concerns that using fertility drugs might raise a woman's chances for later developing ovarian cancer, new research suggests the drugs don't contribute any added risk. More

Study reveals natural process that blocks viruses
University of Southern California via Medical Xpress
The human body has the ability to ward off viruses by activating a naturally occurring protein at the cellular level, setting off a chain reaction that disrupts the levels of cholesterol required in cell membranes to enable viruses to enter cells. More

Broad MRSA screening in UK not cost-effective
Medscape Medical News
The current methicillin-resistant Staphylococcus aureus screening policy in place at the National Health Service in the United Kingdom is not cost effective, new research suggests. The NHS recently switched from a policy of screening only high-risk patients to one of routinely screening most patients admitted to the hospital.More

Violence as an infectious disease? A program that worked
Medscape Medical News
Does violence spread like a disease? Epidemiologist Gary Slutkin, M.D., began to think so when he returned home to his native Chicago after spending years in Africa battling epidemics. Traditional methods of controlling street violence were yielding minimal results, so Dr. Slutkin, who is currently a research professor in epidemiology at the University of Illinois, Chicago, and founder and executive director of Cure Violence, decided to apply the lessons he learned fighting infectious diseases to a new public health model to reduce violence.More