ASCLS eNewsBytes
Jun. 16, 2015

Could daily aspirin prevent breast cancer?
Medical News Today
Conducted by Dr. Sushanta Banerjee, research director of the Cancer Research Unit at the Veterans Affairs Medical Center in Kansas City, Missouri, and colleagues, the study revealed how low-dose aspirin impaired the ability of breast cancer cells to renew. The researchers say their findings suggest a daily dose of aspirin — a medication commonly used to relieve pain and prevent blood clots — could prevent breast cancer development and recurrence in women.More

New trial tests whether TB shot fights Type 1 diabetes
Researchers are launching a clinical trial to see if a vaccine approved long ago to prevent tuberculosis may also hold promise as a treatment for type 1 diabetes. The proposed five-year study is designed to investigate whether repeated injections of the tuberculosis vaccine bacille Calmette-Guerin (or BCG vaccine) can quiet the immune system attack that causes type 1 diabetes and improve blood sugar levels in people with long-standing diabetes. More

Stem cell discovery paves way for targeted treatment for osteoarthritis
Health Canal
Researchers in the Departments of Biology and Physics at York, working with colleagues at the Erasmus Medical Center in Rotterdam, have identified individual stem cells that can regenerate tissue, cartilage and bone. The stem cells are mixed within human bone marrow stromal cells (MSCs) but are similar in appearance and previously, scientists had difficulty in distinguishing between them.More

Quadruple anti-HCV regimen highly effective in HCV/HIV coinfected individuals
A four-drug anti-HCV regimen provides sustained virological responses (SVR) in most individuals coinfected with HCV and HIV, researchers from France report. "It is possible to cure nearly all these difficult-to-treat patients with such a combination, which could be of interest as a second-line or salvage approach," Dr. Lionel Piroth from Université de Bourgogne in Dijon told Reuters Health by email.More

'Silent' Celiac Disease found in kids at rheumatology clinic
Celiac disease was twice as common in children presenting for rheumatology evaluation as in the general population, and musculoskeletal symptoms in those with the disease resolved with a gluten-free diet.More

UCLA researchers develop lens-free smartphone microscope, pathologists may be able to take the clinical pathology laboratory just about anywhere
DARK Daily
At UCLA, Professor Aydogan Ozcan, Ph.D. is already well known for having invented attachments that use a smartphone's camera to create a tiny, lens-free microscope. Now Ozcan, who is the Chancellor's Professor of Electrical Engineering and Bioengineering at the UCLA Henry Samueli School of Engineering and Applied Science, has created an inexpensive smartphone device that produces holographic images of tissue samples that allow pathologists to view cancer and other abnormalities at the cellular level, according to a Dec. 17, 2014, Science Translational Medicine (STM) article. More

As MERS outbreak surges, genetic tests show virus hasn't mutated
An outbreak of the Middle East respiratory syndrome, or MERS, has swelled to 95 cases in South Korea. Seven people have died, and scientists are trying to figure why the outbreak has grown so rapidly. Although there's no vaccine or treatment for MERS, the disease isn't usually very contagious.More

Study: Boosting gut bacteria defense system may lead to better treatments for bloodstream infections
Lab Manager
In the study, published online in Nature Medicine, scientists identified how a certain transcription factor — a protein that that turns genes on and off — works in partnership with a naturally occurring antibiotic to kill infection-causing fungi called Candida albicans. These particular fungi, best known as a cause of yeast infections and oral thrush, can be lethal if they overgrow and invade the bloodstream from the gut. More

Vaccine kicked rotavirus to the curb in a few short years
Within six years of the introduction of the rotavirus vaccine, hospitalizations for the diarrheal illness had dropped by 94 percent and hospitalizations for overall gastrointestinal illnesses were cut in half. Those are the findings of CDC-funded research published in JAMA recently.More