ASCLS eNewsBytes
Aug. 25, 2015

Study: Hope for some human stem cell therapies
University of California, San Diego via ScienceDaily
An international team of scientists has discovered that an important class of stem cells known as human-induced pluripotent stem cells, which are derived from an individual's own cells, can be differentiated into various types of functional cells with different fates of immune rejection.More

Newly discovered cells restore liver damage in mice without cancer risk
National Institute of Environmental Health Sciences via Lab Manager
The liver is unique among organs in its ability to regenerate after being damaged. Exactly how it repairs itself remained a mystery until recently, when researchers supported by the National Institutes of Health discovered a type of cell in mice essential to the process. The researchers also found similar cells in humans.More

Experimental MERS vaccine induces immunity in rhesus macaques
Outbreak News Today
A novel synthetic DNA vaccine can, for the first time, induce protective immunity against the Middle East respiratory syndrome coronavirus in animal species, reported researchers from the Perelman School of Medicine at the University of Pennsylvania. David B. Weiner, Ph.D., a professor of pathology and laboratory medicine, and colleagues published their work in Science Translational Medicine. More

New microfluidic blood-draw device could replace needle sticks and venipunctures at medical laboratories
DARK Daily
For more than two years, the nation's media have been captivated by Theranos CEO Elizabeth Holmes' vision of offering patients who need blood tests a finger stick collection instead of a venipuncture. Meanwhile, in research labs across the nation, there are credible efforts to develop ways to collect medical laboratory test specimens that require no needles at all. More

Scientists say they've grown the world's most complete petri dish brain
The Washington Post
It's a tiny little thing, no bigger than a pencil eraser and certainly not capable of thinking for itself, but it's got all the major structures and 99 percent of the genes present in the brain of a 5-week-old fetus. In other words, scientists at Ohio State University say it's the most complete model of a human brain ever grown in a lab.More

Insulin pumps nearly halve risk of heart disease death for Type 1 diabetics
HealthDay News
People with Type 1 diabetes who use insulin pumps seem to have a much lower risk of dying from heart disease or stroke prematurely than those who rely on multiple daily injections of insulin, new research suggests. "As done in Sweden at the time of this study, insulin pump treatment almost halved cardiovascular mortality," said study author Dr. Isabelle Steineck from Aarhus University Hospital in Denmark.More

Study: Results of genetic testing for 22 genetic causes of neonatal diabetes
University of Exeter via News-Medical.Net
Over a 10-year period, the time that babies receive genetic testing after being diagnosed with diabetes has fallen from over four years to under two months. Pinpointing the exact genetic causes of sometimes rare forms of diabetes is revolutionizing healthcare for these patients. More

Side effects may lead breast cancer patients to skip drugs
Reuters
Breast cancer patients who report more side effects of their hormone therapy drugs and less confidence communicating with their doctors are more likely to intentionally or unintentionally miss a dose, according to a new study. "Endocrine" therapy, given as a daily tablet that acts to prevent hormones from helping the tumor to grow, is an important part of treatment for some types of early breast cancer. More

Migrating cancer cells alter bone tissue to form tumors
Medical News Today
Most people who die from cancer die from metastatic disease — where tumor cells migrate from the original site and start growing tumors in other parts of the body, such as bone. Now, new research reveals fresh clues on how migrating cancer cells alter bone tissue to make it suitable for tumor growth.More

Researchers suggest approach to fight adenoviruses in immunosuppressed patients
Saint Louis University via Infection Control Today
Using an animal model they developed, Saint Louis University and Utah State University researchers have identified a strategy that could keep a common group of viruses called adenoviruses from replicating and causing sickness in humans. "The adenovirus can cause colds and infections in the eyes and respiratory system and generally are not serious," says William Wold, Ph.D., senior author of the paper and chair of molecular microbiology and immunology at Saint Louis University. More