ASHI Insights
Apr. 7, 2015

Technologist survey is on its way!

The ASHI Technologist Affairs Committee has been working hard and all HLA technologists in North America should be receiving the survey via email soon. This survey is completely anonymous and consists of general questions like location and gender to more specific questions like salary information and compensation for on-call pay. Please take time to thoughtfully answer each question and feel free to add any comments or other information at the end of the survey. Our goal is for each North American HLA technologist to have the opportunity to take this survey so if someone in your lab did not receive the email link please forward the email to them. Once the survey results are tabulated, the summary will be made available on the ASHI website inside the member’s only section.

The ASHI Technologist Affairs Committee wants to thank you in advance for your participation in this important survey!!More

2015 Call for Award Nominations

Know someone who should be publicly acknowledged for his/her contributions to histocompatibility and immunogenetics? ASHI has opened nominations to the membership for the following awards!

ASHI RISING STAR AWARD An outstanding HLA technologist who has worked in the field fewer than three years and desires to pursue a career in HLA *Short essay* of fewer than four pages describing his/her current work in HLA and why he/she is interested in pursuing a career in HLA

*Essay must be written by the nominee and validated by his/her Lab Director
ASHI DISTINGUISHED SERVICE AWARD ASHI membership past or present, doctoral or non-doctoral. Creativity in moving ASHI in new directions, scientifically and as an organization

Service to ASHI

Educational contribution on behalf of ASHI

Other extraordinary contributions (please explain)
*Letter of nomination from an ASHI member

*Two additional supporting letters

*Candidate's curriculum vitae
ASHI DISTINGUISHED SCIENTIST AWARD *ASHI membership past or present, doctoral or non-doctoral

*Professional scientific accomplishments: theoretical and technical creativity

*Special contributions and achievements in their field of expertise

*Other extraordinary contributions (please explain)
*Letter of nomination from an ASHI member

*Two additional supporting letters

*Candidate's curriculum vitae

ASHI membership is not required
*Distinguished scientific accomplishments in the field of histocompatibility and immunogenetics

* Contributions to the advancement of histocompatibility and immunogenetics

*Other extraordinary contributions (please explain)
*Letter of nomination

*Two additional supporting letters (only one required if nominator is an ASHI member)

*Candidate's biosketch and curriculum vitae

ASHI membership (non-doctoral) is required.
*Contributions to advancement of technology and science of HLA immunogenetics

*Service to ASHI or ABHI as a committee member, director, officer, etc.

*Educational contributions on behalf of ASHI at a regional or national level

* Certification in histocompatibility

* Other extraordinary contributions (please explain)
*Letter of nomination from an ASHI member

*Two additional supporting letters

*Candidate's curriculum vitae

*Cannot have previously received the award

If you've submitted a nomination in the past and that nominee has not been recognized, please contact the ASHI office to update and resubmit the nomination.

Return nominations & supporting documentation by June 1, 2015 via email to: Katherine Miranda, ASHI Executive Director — kmiranda@ahint.comMore

Medical Laboratory Professionals Week, April 19-25, 2015

2015 Lab Week is the time to honor more than 300,000 medical laboratory professionals around the country for their hard work and dedication to the field.

During Medical Laboratory Professionals Week, April 19-25, 2015, the American Society for Histocompatibility and Immunogenetics (ASHI) will celebrate our members who play a vital role in optimizing patient care. Because they often work behind the scenes, few people know about the critical testing laboratory professionals perform each day.

ASHI is pleased to offer our accredited labs this poster to display during Lab Week and beyond. Please hang this poster prominently to show that you are proud to be an ASHI-accredited lab!

This year we are also offering a virtual badge for all ASHI-accredited labs and individual ASHI members. Proudly display this badge on your Facebook page and in your email signature, so your peers know that you are part of ASHI.More

ASHI San Antonio Education Workshop Deadline Reminders!

The San Antonio Education Workshop is quickly approaching. The hotel deadline is Thursday, April 9, 2015. Book now to secure your room and be steps away from educational programming developed with you in mind.

Hotel Deadline: April 9 (click here to book now!)

Book your room today at the Marriott Plaza San Antonio! ASHI Discounted Room Rate: $159+tax

Registration deadline: April 22 (click here to register now).

For more details, click here.More

Different strokes for different folks: concordance and discordance in anti-hla antibody testing
Human Immunolgoy
Correct identification of the specificity of antibodies directed against HLA using Single Antigen Luminex Beads (SALB) is essential in current HLA laboratory practice for transplantation. The cumulative data collected by the Proficiency Testing (PT) Program from hundreds of laboratory submissions over years of activity provide an invaluable opportunity to study concordance in antibody testing in a broad group of HLA laboratories. The aim of this study was to investigate the magnitude of concordance and discordance among laboratories in testing for anti-HLA antibodies using SALB.More

The ultimate mix and match: making sense of HLA alleles and peptide repertoires
Immunology & Cell Biology
Human leukocyte antigens class I (HLAIs) display protein fragments (~9–13 amino acid peptides primarily generated by proteasomal cleavage of cytosolic proteins) at the cell surface to the adaptive immune system (principally CD8+ T cells). If CD8+ T cells recognize these presented protein fragments, they have the ability to destroy the contaminated cell. HLAIs represent one of the most diverse set of alleles in the human genome, probably an evolutionary safeguard that ensures comprehensive immune disease coverage across the human population. Thus, it is not surprising that particular HLAI alleles are genetically associated with susceptibility to, or protection against, a number of diseases including; HIV-1, type 1 diabetes and ankolysing spondylitis. More

German team develops high Resolution HLA-typing method; Claims lower cost than commercial offerings
Researchers at the University of Kiel in Germany have developed a next-gen sequencing-based HLA-typing and analysis pipeline that they say provides an alternative to commercially available solutions at a lower cost per sample. The method, published in Nucleic Acids Research, combines hybridization-based target capture with Illumina sequencing and open-source allele-calling software.More