ASHI Insights
Aug. 25, 2015

ASHI Annual Meeting housing information

Housing Reservation Deadline: September 2!

The Westin Savannah has already sold out! Don't wait to book your hotel rooms, as space is limited in the two remaining hotels!

ASHI has negotiated discounted rates at the following hotels:

Hyatt Regency Savannah Marriott Savannah Riverfront
(10 mins via ferry to the Convention Center) (10 mins via ferry to the Convention Center)
ASHI Discounted Rate: $170+tax ASHI Discounted Rate: $189+tax

If you would like to make a reservation via telephone or have any questions, please call the Savannah Housing Bureau at (912) 644-6465 during the business hours of 8:30 a.m.-5 p.m. (EST).

Book online now! More

ASHI's 5K Fun Run/Walk $25

Wednesday, September 30 — 6:30 a.m.-8:30 a.m.

Join us for ASHI's 3rd Annual Run for a Life 5K Fun Run/1 Mile Walk. Proceeds from this event will benefit a local association related to the transplantation field.

This year's fun run will take place on Hutchinson Island directly in front of the Westin Savannah, so roll out of bed, throw on your running shoes and be part of something great! Sign up when you register!More

2015 revisions to 2014 ASHI Standards — Now open for public comment

The Quality Assurance and Standards Committee (QAS) has been working on updates to the 2014 ASHI Standards. There are a large number of recommended revisions, but we wish to draw your particular attention to the following:

A.2 - A new abbreviation section has been added

D.5.3.8 - A new section on Virtual Crossmatching has been added.

These proposed changes to the Standards have been submitted to the ASHI Board and the Accreditation Review Board (ARB) for review and comment. Now we seek your comments and suggestions.

Click here to view a redline version of the proposed 2015 Standards. Please carefully consider these proposed changes to the current standards and send your comments to Deb Dupnik at ASHI Headquarters no later than Sept. 5, 2015.

QAS will respond to all comments received during the public comment period.

Please remember that the QAS Committee has certain constraints when responding to your comments. There are two that are noteworthy. First, the proposed standards may not be made more stringent based upon membership comments without a subsequent round of public comment; therefore, such comments will be deferred until the next round of revisions unless the comments are of extraordinary importance. Second, all ASHI Standards must be at least as stringent as the CMS (CLIA) regulations; therefore, proposals that advocate lesser stringency cannot be considered.

QAS has worked together to get the proposal to this point; now we need your input. All comments received will be addressed by QAS and our responses will be posted on the ASHI website later this year. We are most appreciative of your participation in the continual improvement process for the ASHI Standards. Thank you in advance for your time. More

Four ASHI Travel Awards are now available!

Submit your application by Monday, Aug. 31 for your chance to win $1000 towards your travel expenses to the ASHI Annual Meeting in Savannah, Georgia, from Sept. 28-Oct. 2, 2015!

The Travel Fund Award was created to help new ASHI members attend the annual meeting. The ASHI Board of Directors recently approved 4 grants for the 2015 Annual meeting in Savannah, Georgia. Two grants have been reserved for Technologist members and two for Doctoral level members.

In order to be considered for the ASHI Travel Award, you should:

Please complete this application and return it with your CV to Katherine Miranda, Executive Director, at by Monday, Aug. 31.More

Instructional program recording announcement

"VCAs Have Arrived" Recording Available

This video reviews the criteria defining a vascularized composite allograft and covers the VCA transplantation process, starting at the OPO and ending at the transplant hospital.

OPOs and transplant hospitals interested in involvement with VCA transplantation.

A recording is now available. It lasts approximately 14 minutes and can be accessed here. The objectives are as follows:

Evaluation and Assessment
Once you have viewed the recording, click here to access the evaluation and assessment.

Other Resources
Additional information and resources on VCA transplantation can be found on the OPTN and Transplant ProSM websites.

If you have any questions, please contact UNOS Instructional Innovations at

HLA-E coding and 3' untranslated region variability determined by next-generation sequencing in two West-African population samples
Human Immunology
HLA-E is a non-classical Human Leucocyte Antigen class I gene with immunomodulatory properties. Whereas HLA-E expression usually occurs at low levels, it is widely distributed amongst human tissues, has the ability to bind self and non-self antigens and to interact with NK cells and T lymphocytes, being important for immunosurveillance and also for fighting against infections. HLA-E is usually the most conserved locus among all class I genes. More

High HLA-DP expression and graft-versus-host disease
The New England Journal of Medicine
Transplantation of hematopoietic cells from unrelated donors can cure blood disorders but carries a significant risk of acute graft-versus-host disease (GVHD). The risk is higher when the recipient and donor are HLA-DPB1–mismatched, but the mechanisms leading to GVHD are unknown. The HLA-DPB1 regulatory region variant rs9277534 is associated with HLA-DPB1 expression. We tested the hypothesis that the GVHD risk correlates with the rs9277534 allele linked to the mismatched HLA-DPB1 in the recipient. More

When personal identity really Matters: Donor's reported ancestry depends on question format
For years, medicine has relied on self-reported race/ethnicity as the basis of an array of decisions, from risk for disease to matching organ donors. Now, a study led by researchers at UC San Francisco has found that when that information matters most — in connecting bone marrow donors to patients — the format of the questions may determine how well the answers actually correspond to their genes. More