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Mark your calendar now for future ASHI Annual Meetings!
Abstract Submission Now Open
The abstract submission site is now open for the ASHI/BANFF Joint Scientific Meeting. Abstracts may be accepted for either an oral presentation or a poster presentation. Before you prepare and submit your abstract, please carefully review the policy.
Submission Deadline: Monday, April 8, 2019 at 11:59 PM CT
Registration and housing for the ASHI Regional Education Workshop 1 at the Crowne Plaza Portland Downtown Convention Center in Portland, Oregon from April 11-13, 2019 is now open! Early bird and housing deadlines for Regional 1 are Thursday, March 14.
CASE STUDY SUBMISSION
ASHI Regional Education Workshop faculty request case studies from attendees for the ASHI 2019 Regional Education Workshops. Case study submission deadline is Monday, March 11.
ASHI TRAVEL AWARD FUND
Do you need funding to attend this meeting? ASHI members can apply for a travel stipend. Click here to complete the application. Application deadline is Friday, April 26 for Regional 2.
The Technologists’ Affairs Committee created a word search puzzle in the Quarter 3 issue of the ASHI Quarterly. The word search puzzle was published without a key, so technologists had to find as many HLA related words as possible. The lab or technologist that submitted the most HLA related words would be declared the winner… and the results are in!
Lehigh Valley Hospital HLA Lab in Allentown, PA
with a total of 158 words found!
Avera McKennan HLA Lab in Sioux Falls, SD
with a total of 116 words!
- Tips on how to keep your lab stockroom and cold reagents organized: READ MORE
- Dr. Robert Liwski, HLA Lab Director, developed and validated a rapid optimized flow cytometry crossmatch (FCXM) Assay: READ MORE
- Get a wallchart with an overview of the HLA molecule, genes and nomenclature: REQUEST FREE WALLCHART
- Are you processing too many samples? Automate cell isolations with RoboSep™: WATCH VIDEO
Sunday, July 14 - Wednesday, July 17, 2019
Marriott Springhill Suites Old Montreal
Registration is now open!
The application for the 14th International Summer School on Immunogenetics is now open! Before preparing to apply, please review all the meeting requirements.
Deadline: Friday, March 22, 2019
Important Note: This application requests a copy of the participants curriculum vitae, letter of motivation, abstract of own research that you will present to the attendees, letter of support from your mentor/supervisor/sponsor and copy or verification of society membership with either APHIA, ARSHI, ASHI or EFI.
For more information on the faculty,
Your lab could receive up to $1,000 for hosting a local HLA meeting! ASHI has prepared all the tools you need to organize your local meeting including an ASHI Local Meeting Handbook. Ready to get started? Just submit an application for funding. Applications are reviewed on an ongoing basis.
Name & Credentials: Ping Rao Ph.D.
Title: Assistant Director
Employment: Duke University
Graduated from: University of Texas at Austin
How long have you been an ASHI member? 7 years
Where was the ASHI meeting held the first time you attended? My first ASHI meeting was in 2011 in New Orleans.
Click here to read more.
To be our next ASHI Member Spotlight, click here now! You can also nominate a co-worker or fellow colleague by contacting Mandi Cruz at Mcruz@ashi-hla.org.
2019 HT-1 survey is scheduled to ship on Tuesday, February 19th. PT results for the HT-1 survey must be submitted by Friday, March 29th.
The next survey is the 2019 AC-1 survey. It is scheduled to ship on Tuesday, April 9th. The
2019 PT shipping schedule for the 2019 surveys can be found on the PT page of the ASHI website.
The 2018 Summary and Performance Reports for EMO-2 are now available in the PT Lab Center. To access the reports, login to the Lab Center with your username and password, select Reports then Summary or Performance Report.
The Summary and Performance reports for 2018 AC-2 are in the process of being finalized. The next Insights will contain further information regarding the release date for the 2018 AC-2 Summary and Performance reports. Thank you for your patience as the reports are being finalized.
The data and analysis of the 2018 Educational Virtual Crossmatch-1 can be found on the PT page of the ASHI website. You can view the
and the graphs by using the links on the ASHI PT Page. The article will also be included in the next issue of the ASHI Quarterly (2018 4th quarter edition) which is due to be released soon.
The Directors’ Training Review and Credentialing Committee (DTRC), in addition to its role in evaluating future HLA Laboratory Directors, provides general follow-up and guidance to candidates at different stages of their training. One important aspect of any HLA Laboratory Director Training Program is the preparation of a portfolio of clinical cases to be submitted to the DTRC for assessment of the candidate’s competency as a future HLA Laboratory Director.
In an effort to help directors-in-training prepare their portfolios, the DTRC has asked newly-approved candidates who submitted outstanding portfolio cases to share them. Some of these cases are presented in a new
ASHI-U module, entitled “Volume 6”. They are intended to provide directors-in-training with examples of case build-ups that meet or exceed portfolio reviewer expectations.
here to read more.
Check out ASHI's newest volunteer opportunities!
Click here to learn more about ASHI committee roles and responsibilities.
Looking for a small way to give back? Contact Mandi Cruz at Mcruz@ashi-hla.org for a list of opportunities!
If you are interested in volunteering, click here to complete the volunteer application.
The American Foundation for Donation and Transplantation (AFDT) Basic Histocompatibility Course will be held on March 8-11, 2019 at the Hyatt Centric French Quarter in New Orleans, LA. Click
here for the brochure.
Registration is now open!
Click here to register today.
HLA-F is one of the most conserved loci among the HLA gene family. The exact function of HLA-F is still under investigation. HLA-F might present tolerogenic features, participate in the stabilization of HLA molecules in open conformation, and also participate in the recycling of HLA molecules. Here we evaluate the variability and haplotype structure of the HLA-F distal promoter segment (from −1893 to −943) and how this segment is correlated with the coding region.
Virus-specific T cells have been shown to cross-react with allogeneic HLA (allo-HLA) at a clonal level. However, the impact of a single virus on the allorepertoire has never been investigated at the polyclonal level.
We made an inventory of the incidence and specificity of allo-HLA-cross-reactive-virus-specific CD8+ T cells in 24 healthy individuals. T cells were stained for 25 virus-specific tetramers, and mixed-lymphocyte reactions were performed against a panel of HLA-typed allostimulators. Allospecificity was confirmed by IFNγ-ELISA using T-cell clones against a panel of HLA-typed cell-lines.
The International Registry of HLA Epitopes is a website-based resource for HLA epitopes important in transplant rejection and platelet transfusion refractoriness. Its primary goal is to document epitopes that are verified experimentally with specific antibodies. Such epitopes can be defined by single eplets and by eplets paired with certain polymorphic residues within a 15-Å radius, the dimension of the corresponding structural epitope.
American Journal of Transplantation
Antibody‐mediated rejection (ABMR) is defined by specific histopathological lesions and evidence of circulating donor‐specific antibodies (DSA). Although DSA are not always detectable, monitoring donor‐reactive memory B cells (mBC) could identify patients at risk of developing ABMR.
American Journal of Transplantation
Alloimmune risk stratification in renal transplantation has lacked the necessary prognostic biomarkers to personalize recipient care or optimize clinical trials. HLA molecular mismatch improves precision compared to traditional antigen mismatch but
has not been studied in detail at the individual molecule level.
*As recommended by the Science & Technology Initiatives Committee
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