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The Evolution of Transplantation
The American Society for Histocompatibility & Immunogenetics is pleased to announce Dr. Allan Kirk, MD, PhD of Duke University Health System as our Keynote speaker at the 2018 Annual Meeting on Tuesday, October 2 at 8:30 AM.
Dr. Kirk is the David C. Sabiston, Jr. Distinguished Professor of Surgery at Duke University. He also holds secondary professorships in Immunology and Pediatrics, and serves as Chairman of the Department of Surgery and Surgeon-in-Chief for the Duke University Health System. Dr. Kirk received his MD and PhD in Immunology at Duke, and completed a surgery residency at Duke. Click here to read more.
Discounted Registration Rates Available
Take advantage of discounted rates by registering early for the meeting. The early discount deadline is August 15, 2018 at 11:59 CT. Click here to register today!
Book Your Housing Now
Staying in the official block helps support ASHI and connects you directly to all meeting activities. Rooms are available on a first-come, first-served basis, so book early to secure your spot. The discounted rate is available until September 6, 2018. Click here to book your room!
Preliminary Program Available
The preliminary meeting program is now available so start planning your agenda early. Click here to view the preliminary program!
Hilton Garden Inn Cleveland Downtown
June 28-30, 2018
Join ASHI in Cleveland! Register and book your hotel now.
Do you have an innovative idea that could lead to an increase in organ donation, organ utilization, or organ transplantation? Submit it now for a chance to present it at the 2018 National Critical Issues Forum! It may be a new concept or an application of learning from other industries. The top-rated pitches will be selected for presentation at the 2018 National Critical Issues Forum.
Forum attendees will cast votes based on criteria as it relates to innovation, feasibility, and value to the donation and transplantation community. A selection committee will identify the winning pitch which will be taken on as a national project by The Alliance. Click here to submit your idea before the June 29 deadline!
For the 11th consecutive year, ASHI is co-sponsoring two symposia at the FOCIS meeting in San Francisco later this month. Organized by Dr. Elaine Reed, ASHI's liaison to FOCIS, the jointly sponsored symposia will take place on Wednesday, June 20. The morning session is entitled "HLA as the Target of the Transplant Response" and is sponsored by ASHI, AST & TTS. The afternoon session is entitled "Fine Tuning the Immune System: Spotlight on Immune Therapies for Autoimmune Disorders, Cancer, and Transplantation" and is sponsored by ASHI & the Association of Medical Laboratory Immunologists (AMLI). Click here to view the full schedule.
VxMatch now features full LIMS integration, MFI cut-offs and custom visualizations. VxMatch is a dedicated application that displays DSA trends, dilution and reactivity history and has been validated at leading HLA labs. Click here to schedule a full demo or view our recent ASHI poster on VxMatch to learn more.
Michael D. Gautreaux, PhD, D.ABHI
A couple of years ago, ABHI was contacted by a task force of the Association of Pathology Chairs about its role in credentialing PhD. professionals in clinical laboratory practice. As part of the ABHI executive leadership at the time and having recently rotated off of the ASHI ARB, I was asked to become part of a group (the PhD Data Task Force) that wanted to investigate how PhDs. are trained for a role in the clinical laboratory workforce. The article, linked below, about the PhD clinical lab workforce just came out from a collaboration of the Association of Pathology Chairs and various professional societies including ASHI. The collection of data and this article was many years in the making. Many thanks go to ASHI's own, Melissa Weeks, who was instrumental in getting the data for ASHI. Thanks also go to ASHI's ARB, DTRC and the Board of Directors for comments, discussions and permission for using ASHI's data.
One of the biggest conclusions that the PhD Data Task Force made from our research is the realization that many graduate schools do not include much information about opportunities for clinical laboratory science and medicine in their curricula. We on the Task Force hope that this article will find its way to pre-doctoral students and post-doctoral fellows wishing to obtain information about careers outside of basic research. It is my wish that if you know someone in graduate school or a post-doctoral fellowship, please send this link to them. Click here to read the article.
Journal: Academic Pathology, Volume 5, Pages 1-8
Article title: The Pathology Workforce and Clinical Licensure: The Role of the PhD Clinical Laboratorian in the United States
The 18th IHIWS is being organized by Dr. Sebastiaan Heidt and Dr. Eric Spierings in Amsterdam, Netherlands. The meeting will be held on May 6-10, 2021 at the Westergasfabriek. The 18th IHIWS will be supported by the Dutch HLA Working Party (HLA-WN), consisting of many internationally respected professionals in the Immunogenetics and Histocompatibility field. The organizing committee has a strong commitment and aims to be very active in making sure all goals of the workshop are reached.
Click here to view the preliminary program.
The 35th EFI Conference
The 18th IHIWS will be followed by the 2021 annual EFI meeting in Amsterdam, Netherlands. This joint structure will allow for the participants of the 18th IHIWS to join the 2021 annual EFI meeting.
Follow the News
More information will soon be available via the IHIWS website.
Subscribe to the newsletter to receive regular updates on projects and progress, click here.
The 37th and the 33th Current Courses on Immunogenetics & Molecular Genetics
Week I: July 23, 2018 - July 27, 2018
Week II: July 30 -August 3, 2018
Courses include all meals, a USB with all recorded sessions, lab manuals for 2nd week participants and a DVD with almost 300 articles. Click here to read more!
ASHI and the American Society of Transplantation (AST) partnered to support a workgroup comprised of experts in all transplant-related fields including Histocompatibility, Nephrology, Hepatology, Cardiology, Pulmonology, Pathology and Basic Science. This workgroup discussed current knowledge and provided recommendations for alloimmune sensitization in the context of solid organ transplantation (Sensitization in Transplantation: Assessment of Risk – STAR). An overview of this process was presented on the last day of the ASHI 2017 annual meeting. An executive summary was published in the March 2018 issue of the American Journal of Transplantation.
The STAR initiative is likely to continue as ongoing discussions at future meetings and will be open for audience participation. More details to come.
ASHI would like to acknowledge and thank all of the STAR initiative supporters.
Did you know that ASHI offers reimbursement of up to $1,000 for you to organize a local HLA meeting at your lab/institution?
Interested? Click here to get started!
Name & Credentials: Marian S. Tamondong-Reside, BSMT, CHS(ABHI)
Job Title: Laboratory Manager, Serology
Place of employment: ClinImmune Labs
Graduated from: Trinity College of Quezon City, Philippines
How long have you been an ASHI member? 18 years
When did you attend your first ASHI Meeting? The first ASHI Meeting I attended was the 36th Annual meeting in Hollywood, Florida (2010). I was so excited to finally meet other colleagues in the field. I also attended my first Inspector Training Workshop there. Little did I know, it started me on the path of becoming an inspector and currently a commissioner for the ARB. Since the first meeting I have met so many amazing people and friends.
Click here to read more.
To be our next ASHI Member Spotlight, click here now! You can also nominate a co-worker or fellow colleague by contacting Mandi Cruz at Mcruz@ashi-hla.org.
HT-1, AC-1, EMO-1, and Educational Virtual Crossmatch Challenge
The PT Committee is in the process of grading the results for the HT-1, AC-1, and EMO-1 surveys as well as the Educational Virtual Crossmatch Challenge. Please be aware that an extensive grading and review process is necessary to ensure consensus among the committee members and accuracy in the reports. Since the process is complex and details may arise that require further evaluation and discussion, the completion process may occasionally take longer than originally planned. The PT committee appreciates your patience as you await the reports for each survey.
Laboratories will be notified by email once the grading process for each survey has been completed and the reports have been finalized. Final reports will be posted in the new Lab Center and can be accessed with individual account logins after the announcement for each report has been sent.
Dr. Effie Petersdorf and ASHI Member/Board Member, Dr. Rob Liwski, are confirmed speakers at the Asia–Pacific Histocompatibility & Immunogenetics Association (APHIA) conference held on November 11 – 14, 2018 at the Sydney Masonic Center in Sydney.
Click here for additional conference details or visit aphia2018.org.
Do you want to learn new skills? Meet new people? Advance in your career? Sign up to be an ASHI Volunteer! Learn more about the many benefits of volunteering by visiting the ASHI WANTS YOU volunteer page on the ASHI website.
We also offer several easy, low-commitment tasks. So, if you are not sure about volunteering, or simply can't make a full commitment, try out one of our micro-volunteering opportunities. Sign up today by clicking here!
Chronic-active antibody-mediated rejection (CAABMR) is associated with poor kidney graft survival and has no clear effective treatment. Forty-one cases of CAABMR were detected in indication graft biopsies and evaluated according to current Banff classification. We investigated the impact of concurrent donor-specific antibodies (DSA) and their characteristics, together with non-adherence regarding immunosuppression on CAABMR histopathological phenotypes and prognosis.
The trade-off from HLA class I expression to HLA-G expression support the immune evasion of malignant cells. The essential role of the virtually invariant HLA-G in immune tolerance, tumor immunology and its expression frequency in immune privileged tissues is known; however the specific importance of allelic subtypes in immune responses is still not well understood.
Two novel HLA class II alleles, DRB4*03:01N and DQB1*03:276N, containing large deletions were identified during routine typing. Extraction of DNA encompassing the deletions was carried out with a panel of capture oligonucleotides followed by whole genome amplification.
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