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Mark your calendars for these featured events at the 2018 Annual Meeting in Baltimore!
Pre-Meeting Symposium: There is No "I" in HLA: Skills for Leadership and Team Building
Successful leadership is independent of titles, seniority, or personal attributes. The goal of this session on Monday, October 1 from 1:00-5:00 pm is to explore evidence-based practices to unlock motivation in your own workplace and develop the skills necessary to become a leader.
Featuring an exclusive presentation from Christopher Myers, PhD of the Carey Business School at Johns Hopkins University - this is a course you won't want to miss! Space is Limited. Read More & Register Now
Tulip Run – 6th Annual 5K Run/1 Mile Walk
Please join us for a morning 5k run or 1 mile walk through Patterson Park in Baltimore on Wednesday, October 3 from 6:30 am – 8:30 am. Proceeds from this event will benefit the Living Legacy Foundation of Maryland. All runners and walkers are welcome.
NEW THIS YEAR! Warm-up with a local yoga instructor who will guide us through gentle stretches to prepare for the run/walk. Begins at 6:00 am. Read more and add the run to your registration today!
Join us to enjoy a night of music, desserts, drinks, dancing, and networking with your colleagues on Thursday, October 4, from 9:00 PM - 11:00 PM. The Networking Event features Dorry Segev as your DJ! Dorry is a transplant surgeon from Johns Hopkins Medical Center who has been a DJ at several transplant-related, highly enjoyable parties. Request a song here! This event is complimentary for all registered attendees; there is no additional fee to attend.
Early Registration Deadline Extended!
Take advantage of discounted rates by registering early for the meeting. The early discount deadline is August 29, 2018 at 11:59 CT. Click here to register today!
Book Your Housing Now
Staying in the official block helps support ASHI and connects you directly to all meeting activities. Rooms are available on a first-come, first-served basis, so book early to secure your spot. The discounted rate is available until September 6, 2018. Click here to book your room!
Throughout 2018, the ASHI Membership Committee released a series of membership surveys. Feedback from our members is critical to improving services and member experiences. Please take a moment to rate your experience with ASHI Membership in the last survey: Career Development.
Responses are due no later than Thursday, August 24. For each survey, ASHI will reward one lucky participant with a $25 VISA gift card!
Name & Credentials: Catherine Gebhart, PhD, D(ABHI)
Place of employment: University of Nebraska Medical Center
Graduated from: University of Nebraska Medical Center
How long have you been an ASHI member? 10 years
When did you attend your first ASHI Meeting? My first ASHI meeting was in Toronto in 2008.
Click here to read more.
To be our next ASHI Member Spotlight, click here now! You can also nominate a co-worker or fellow colleague by contacting Mandi Cruz at Mcruz@ashi-hla.org.
HLA Typing, NGS, almost no ambiguity, Affordable, Accurate, Quick turnaround time. Reports are uploaded to compatible laboratory software. HLA antibody identification by SAB or C1q, KIR typing, Cancer gene screening and many more.
Questions regarding our testing or to discuss your needs, please contact us at 972-566-8478, 972-566-6278 or 972-566-5761 or visit our website at texasmedicalspecialty.com.
The ASHI Technologists’ Affairs committee is pleased to announce ASHI’s newest Facebook groups: Technologists' Affairs Forum and Technologists’ Affairs Mentoring Forum! These forums give you a more convenient way to ask and answer specific technologist-related questions, to get or give advice and guidance on job-related challenges and to receive or offer tips on advancing within the HLA career ladder.
Both forums are private Facebook groups and are solely intended for technologist and non-doctoral members. Click the buttons below and join the discussion today!
The Membership Committee is hosting a Silent Auction at this year’s ASHI Annual Meeting in Baltimore. Visit us in the Exhibitors Hall to place your bid on the basket of your choice. All proceeds will be donated to the ASHI Travel Fund. A special thanks to all of our ASHI committee members for their generous item and basket donations!
Please click here to read more about the Silent Auction at the 2018 ASHI Annual Meeting!
The 2018 Summary and Performance Reports for the EMO-1 survey are now available in the new PT Lab Center under Reports/Summary or Reports/Performance. If you encounter any problems when accessing the reports, a different login may be needed. To access the reports, please login with your personal user account - personal username and password - rather than the Lab Administrator login.
The AC-1 reports are in the final stage of completion. You will be notified by email once the AC-1 reports are available for your review. Your patience has been greatly appreciated as the PT Committee works with the software developers to pinpoint areas in the new ASHI PT software and reporting systems in need of updates and adjustments.
The 2018 HT-2 samples are scheduled to ship on Tuesday, September 11, 2018.
The proposed changes to the ASHI 2017 Standards have been submitted to the ASHI Board and the Accreditation Review Board (ARB) for review and comment. Now, the QAS committee seeks your comments and suggestions.
Click here to view a redline version of the proposed 2017 Standards. Please carefully consider these proposed changes to the current standards and send your comments to ASHI Headquarters no later than August 30, 2018.
QAS will respond to all comments received during the public comment period. Please remember that the QAS Committee has certain constraints when responding to your comments. There are two that are noteworthy. First, the proposed standards may not be made more stringent based upon membership comments without a subsequent round of public comment; therefore, such comments will be deferred until the next round of revisions unless the comments are of extraordinary importance. Second, all ASHI Standards must be at least as stringent as the CMS (CLIA) regulations; therefore, proposals that advocate lesser stringency cannot be considered.
Two new UNOS offerings have been released:
1. HLA Typing – Are you my type?
2. All About HLA Antibodies
Transplanted cells, tissues and organs are seen as foreign to the immune system and can potentially have severe consequences to an organ recipient. What the immune system of the organ recipient sees as foreign are the mismatched, or non-self, HLA proteins of the organ. HLA proteins that are matched between donor and organ recipient can reduce rejection risk and improve organ survival. Thus, the identification of donor-recipient combinations with better HLA matches is important. A major function of the HLA laboratory is the identification, characterization and monitoring of HLA antibodies pre- and post-transplant. Understanding a patient’s HLA antibody status is important to ensure a safe transplant and for helping to guide post-transplant care. These two courses will discuss the basics of HLA typing and HLA antibodies and how this information is used to guide pre- and post-transplant care.
Locate these courses in UNOS Connect by clicking the Learning Series tab on the left of your home page after logging into UNOS Connect. You can also find the courses within the course catalog under the Histo category, click on the course title HST105 "HLA Typing – Are you my type?" and HST106: "All about HLA antibodies" to register. Click the Entrance Survey to begin.
Each course will take approximately 20 minutes to complete.
Continuing Education Information
As a designated Approved Provider by ABTC, UNOS will grant 0.5 Category 1 Continuing Education Points for Transplant Certification (CEPTC) for each course completed. Once you complete the exit survey, your certificate will be available on your transcript.
Interested in additional instructional offerings?
Please visit UNOS Connect for more offerings.
ASHI and the American Society of Transplantation (AST) partnered to support a workgroup comprised of experts in all transplant-related fields including Histocompatibility, Nephrology, Hepatology, Cardiology, Pulmonology, Pathology and Basic Science. This workgroup discussed current knowledge and provided recommendations for alloimmune sensitization in the context of solid organ transplantation (Sensitization in Transplantation: Assessment of Risk – STAR). An overview of this process was presented on the last day of the ASHI 2017 annual meeting. An executive summary was published in the March 2018 issue of the American Journal of Transplantation.
The STAR initiative is likely to continue as ongoing discussions at future meetings and will be open for audience participation. More details to come.
ASHI would like to acknowledge and thank all of the STAR initiative supporters.
Sign up to be an ASHI Volunteer at the 2018 Annual Meeting! We’re looking a few volunteers during exhibit hours to assist with the silent auction. Sign up today by clicking here or contact Mandi Cruz at Mcruz@ashi-hla.org.
Did you know there are two ways to recognize someone in your lab who is going above and beyond?
An ASHI+ can be given to someone for demonstrating one of ASHI's core values: Education, Leadership, Quality, Collaboration, Advocacy, Engagement, Expertise, Patient Advocacy/Service and Responsibility. You can submit a personalized message with your submission and we will feature the ASHI+ on our Facebook page. Click here to send one today!
You can also nominate someone to be featured as ASHI Insights’ Member Spotlight. It’s so simple! Just contact Mandi Cruz at Mcruz@ashi-hla.org to send the name and email address of the person you would like to feature.
We investigated the prevalence of and risk factors for antibodies to HLA in 1663 haploidentical transplant candidates. Among these cases, 349 (21.0%) showed positive panel-reactive antibody (PRA) either for class I or class II HLA. Multivariate analysis showed the following: i) risk factors associated with the prevalence of PRA either for class I or class II HLA were female gender (P = 0.018), prior transfusions (P < 0.001) or pregnancy (P < 0.001), and cases with MDS (P = 0.018); compared to other patients, subjects with ALL had a lower prevalence of class I antibodies (P = 0.017); and ii) risk factors associated with the prevalence of PRA both for class I and class II HLA were female gender (P = 0.014), prior transfusions (P = 0.003), previous pregnancy (P < 0.001), and diagnosis with MDS (P = 0.035).
A challenging task when more than one HLA gene is evaluated together by second-generation sequencing is to achieve a reliable read mapping. The polymorphic and repetitive nature of HLA genes might bias the read mapping process, usually underestimating variability at very polymorphic segments, or overestimating variability at some segments.
We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in a total of 1101 Ecuadorian individuals from three regions of the country, the Coastal region, the Andean region, and the Amazonian region, to obtain information regarding allelic and haplotypic frequencies and their linkage disequilibrium.
50 Minthorn Blvd.Suite 800, Thornhill, Ontario L3T 7X8