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Text Version   RSS   Subscribe   Unsubscribe   Archive   Media Kit          September 22, 2015

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Click here to place your 2015 Proficiency Testing order or to view your previous Performance and Summary reports.

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ASHI U
Access to educational information is free to ASHI members. CECs are awarded through an online testing process and are free to ASHI members.
 




ASSOCIATION NEWS


Schedule at a glance

Want to get a preview of what we have planned for you in Savannah? Click here to download a copy of the Schedule at a Glance.
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If you still haven't registered, there's still time!
Avoid the line!

1. Online
Register online (payment must be made by credit card.)

2. Fax
Complete the registration form in its entirety, including payment information, and fax it to the ASHI headquarters office at 877-716-6404.

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Transportation in Savannah

Free water ferry service between downtown Savannah and the ASHI Annual Meeting location of the Savannah International Trade & Convention Center is available seven days a week from River Street at City Hall Landing (Hyatt) and Waving Girl Landing (Marriott) over to the Trade Center Landing. The ferry service is operated by Chatham Area Transit (CAT). During the ASHI Annual Meeting, there will be additional transportation offered during the meeting days both via bus and water ferry. Click here to view the bus and water taxi schedules.

Click here for some fun things to do while you are in Savannah!

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Accreditation workshop registration
If you plan to attend the Accreditation Workshop on Monday, Sept. 28, you must pre-register!

If you have already registered for the conference, but need to add the workshop to your registration, you can do so by clicking on the link sent in your emailed registration confirmation.

*Please note: you must register for the entire Annual Meeting to attend this workshop.

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OPTN/UNOS Policy and Bylaw Proposals
The proposed changes in OPTN/UNOS policies currently out for public comment include two proposals that will affect your laboratories' testing procedures (see links to those proposals below). The Organ Transplant section of ASHI's National Clinical Affairs Committee prepared "official" ASHI comments about these and one of the other proposed changes. Each of you is strongly encouraged to comment as individuals on these and/or other proposed changes since all comments will be considered in the OPTN/UNOS public comment review process.

Please click here to read all of the current proposed changes and provide your own comments on these proposals.

Proposal to Update the Human Leukocyte Antigen (HLA) Equivalency Tables

Revising Kidney Paired Donation Pilot Program Priority Points

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ASHI U
If you missed the workshops held a few months ago, or just want a little refresher, you can now log in to ASHI University to view them! Under "Educational Offerings", just select "Volume 4 — Additional Continuing Education and Web-Based Learning."

In addition, we also have videos from the 2013 and 2014 ASHI workshops. If you couldn't attend in person, these hour-long videos start at just $10 for members.

If you need certification credits before the end of the year, ASHI-U is a great place to earn them! You can even view study guides for the CHS and CHT exams in Volume 4.4.

There are also numerous other modules available on a range of topics, such as Serology, ELISA, Microbead Luminex Platform, Flow Cytometry, and Molecular Assays.

We hope you enjoy ASHI-U and join us for next year's workshops!

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New HLA basics presentation
The Directors’ Affairs Committee created a new PowerPoint Presentation titled HLA – Basics (or how to recognize "self".) You can view it here.
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Medical Laboratory Professionals Week — April 24-30, 2016

Medical Laboratory Professionals Week is an annual celebration of the medical laboratory professionals and pathologists who play a vital role in every aspect of health care. Lab Week is your chance to let people know about your dedication and commitment to your profession and to quality patient care. What is your lab planning to do to celebrate?

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INDUSTRY NEWS


Donor-specific antibody to trans-encoded donor HLA-DQ heterodimer
Human Immunology
The majority of de novo donor specific HLA antibodies (DSAs) in transplant patients are directed to HLA-DQ antigens, which consist of a heterodimer of alpha and beta chains. Although a heterodimer can theoretically be cis- or trans-encoded, the sensitizing forms appear to be generally cis-forms. DSA to DQ trans-heterodimer has never been reported. We reviewed 360 post-kidney transplant recipients (transplant: 2002-2013; follow-up: 5.6 +/- 3.3 years). DQ DSA was detected in 46 of 57 patients who developed DSA.
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Assessing HLA antibody strength: Have we thought about everything?
American Journal of Transplantation
We read with great interest the article by Tambur et al assessing anti-HLA antibody strength with single-antigen flow bead assays through comparison of classical IgG staining of neat and ethylenediaminetetraacetic acid (EDTA)–treated serum with the C1q and titration assays. The authors concluded that the most accurate approach was the titration assay. Testing a range of serum dilutions seems the best, if not unique, way to bypass the "prozone" phenomenon, whereas the classical IgG assay run with neat and EDTA-treated serum might leave some antibodies undetected that the C1q assay might or might not detect.
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Class II HLA interactions modulate genetic risk for multiple sclerosis
Nature Genetics
Association studies have greatly refined the understanding of how variation within the human leukocyte antigen genes influences risk of multiple sclerosis. However, the extent to which major effects are modulated by interactions is poorly characterized. We analyzed high-density SNP data on 17,465 cases and 30,385 controls from 11 cohorts of European ancestry, in combination with imputation of classical HLA alleles, to build a high-resolution map of HLA genetic risk and assess the evidence for interactions involving classical HLA alleles.
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ASHI Insights
Colby Horton, Vice President of Publishing, 469.420.2601
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Esther Cho, Content Editor, 469.420.2671  
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