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Alcoholism treatment before, after liver transplantation reduces relapse
New research reports that liver transplant recipients who receive substance abuse treatment before and after transplantation have much lower alcohol relapse rates than those untreated or only treated prior to transplantation. A second study determines that continued alcohol abuse following liver transplantation decreases graft survival, further highlighting the importance of preventing alcohol relapse. Both studies are published in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
ASTS Recognition Awards Submissions Open
Submissions are now open for ASTS Recognition Awards. Recognize a faculty member, mentor, or peer who demonstrates outstanding leadership, stewardship, and capacity to train transplant professionals by nominating them for the Francis Moore Excellence in Mentorship in the Field of Transplantation Surgery Award, the Vanguard Prize, or the Advanced Transplant Provider Award. The deadline for nominations is Oct. 25, 2013.
The Living Kidney Donor: New OPTN Policy Requirements for Follow-Up Data Reporting
UNOS will hold a webinar on Nov. 6 at 2 p.m. Eastern to provide an overview of new OPTN policy requirements for living kidney donor follow-up data reporting and strategies that programs may choose to incorporate into their practice to improve donor follow-up.
Help ASTS Celebrate!
A highlight of the Winter Symposium will be the 40th Anniversary Gala, and you can help ASTS celebrate by sending any photos you may have that reflect on the history of the Society. Please look through your old (or not so old) photos and send the ones that catch your eye to firstname.lastname@example.org. Don't worry if you only have prints — just mail them to the ASTS National Office, Attn: Diane Mossholder, 2461 S. Clark St., Suite 640, Arlington, VA 22202, and we will return them to you!
Researchers look at health consequences of living kidney donation
Medical News Today
The short-term risks associated with kidney donation are relatively modest, but because many donors have additional medical conditions, it is important to evaluate their ongoing health. That's the conclusion of a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).
Analysis: Expedited liver allocation in the United States
Liver Transplantation (login required)
The fate of donor livers allocated via an out-of-sequence expedited placement (EP) pathway has not been previously examined. It has been determined that the originating and receiving United Network for Organ Sharing (UNOS) regions of all donor livers procured between Jan. 1, 2010 and Oct. 31, 2012 and placed out of sequence with UNOS bypass code 863 (EP attempt) or 898 (miscellaneous). In this analysis, researchers reviewed the early function of these liver grafts and assessed the effect of EP allocation on wait-listed patients.
Analysis: Post-transplant lymphoproliferative disorder after pancreas transplantation
Clinical Transplantation (login required)
There are not a great deal of data on post-transplant lymphoproliferative disorder (PTLD) following pancreas transplantation. Researchers analyzed the United Network for Organ Sharing national database of pancreas transplants to identify predictors of PTLD development.
Donor risk prediction: How 'extended' is safe?
Current Opinion in Organ Transplantation (login required)
This article reviews recent developments in the selection of the lung donor that aim to increase donor organ use. The scarcity of suitable donor organs continues to limit lung transplantation resulting in long waiting times and significant mortality for those patients awaiting transplantation.
Pretransplant donor-specific anti-HLA antibodies as predictors of early allograft rejection in ABO-compatible liver transplantation
Liver Transplantation (login required)
The significance of preexisting donor-specific HLA antibodies (HLA-DSAs) for liver allograft function is unclear. Previous studies have shown that humoral alloreactivity frequently accompanies acute cellular rejection (ACR). In the present study, researchers set out to determine whether pretransplant HLA-DSAs correlate with clinically significant ACR in the first 90 days after transplantation and, if so, to determine their predictive values.
Science of healing the heart
The Wall Street Journal
A mechanical pump that was invented as a temporary life support for patients with advanced heart failure is emerging as a potential tool to help hearts heal and function for the long term on their own.
The device, called an LVAD, takes over most of the heart's main pumping function and was designed initially to enable patients to survive until a donor heart became available for transplant.
Laboratory-based scoring system for prediction of hepatic inflammatory activity in patients with autoimmune hepatitis
Liver International (login required)
In autoimmune hepatitis (AIH), inflammation is closely related to fibrosis. Although transaminase levels are commonly used to assess hepatic inflammation, they may not relate directly to the histology. A noninvasive diagnostic score has been developed as an alternative to liver biopsy to help optimize treatment for AIH and monitor disease progress.
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