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Get up to date information on nutrition and nutrition research from Michael Greger, M.D. at NutritionFacts.org. Click here to view the website!

Granix is now available in the fight against neutropenia during chemotherapy. Click here to view the USPI! Visit www.granixrx.com for more information.

Click here to view the following free CME/CEU program:
Non-Invasive Pre Natal Testing: What Managed Care Needs to Know

Click Here to view the Journal of Managed Care Medicine

Click Here to view our Complimentary Online CME/CEU Webcasts


Announcing the NAMCP Medical Directors Breast Cancer Resource Center. Click here to visit the website.

On Aug 19, 2013, the FDA issued a label change for ADCETRIS® (brentuximab vedotin). Below is a copy of the updated USPI for your review. Key label changes found within the attachments include:

1. Dosage and Administration Section 1: 16 cycle limitation has been removed from the label. New label states "Continue treatment until disease progression or unacceptable toxicity"

2. Warnings and Precautions Section 5: Growth factor support added for consistency with Dose Modification in section 2.2


CLICK HERE to view the USPI.

The Academy of Oncology Nurse Navigators white paper, "Assessing the Creative Application and Usefulness of NSider: A Tactical Tool for the Oncology Nurse Navigator" was published in the journal, The Oncology Nurse-APN/NP.

Click here to view the white paper.


 




GENOMICS

Express yourself: Novel approach to study how genetic differences affect gene expression
ScienceDaily
Each individual carries a unique version of the human genome. Genetic differences can influence traits such as height, weight and vulnerability to disease, but precisely what these genetic variants are and how they exercise their impact is mostly unknown. UCLA researchers have now developed a novel approach to study the ways in which these individual differences affect how strongly certain genes are "expressed" — that is, how they are translated into the proteins that do the actual work in cells.
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Scientists discover genetic signature mechanism in immune system as driving force for childhood leukaemia
News-Medical.net
Scientists have discovered a genetic signature that implicates a key mechanism in the immune system as a driving force for a type of childhood leukaemia. Acute lymphoblastic leukaemia or all is the most common form of childhood leukaemia. A key factor driving this leukaemia for one in four all patients is a mutation that causes two of their genes, ETV6 and RUNX1, to fuse together.
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23andMe genetic test reveals disturbing artificial insemination switch
LiveScience via Fox News
A young women conceived with help from a fertility clinic in Utah in the early 1990s is actually the biological daughter of the former clinic receptionist, genetic testing reveals. The University of Utah is offering free genetic testing to families who went to the Midvale, Utah, clinic during the late 1980s and early 1990s in the wake of these jaw-dropping revelations.
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PRODUCT SHOWCASE
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BIOTECH/DIAGNOSTICS/PERSONALIZED MEDICINE


With genetic data, Pennsylvania medical center joins effort to forge 'personalized' approaches
NewsWorks
Geisinger Health in Danville, Pa., and New York biotech firm Regeneron Pharmaceuticals are partnering to hunt for new breakthroughs in personalized medicine. In the last decade, scientists have gotten pretty good at scanning individual genetic information and detecting DNA variations. They've been less successful translating that knowledge into "precision" medicine — a tailored fix for a particular health problem.
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DNA sequencer raises doctors' hopes for personalized medicine
MCT Wire via Grand Haven Tribune
Among the many stents, surgical clamps, pumps and other medical devices that have recently come before the Food and Drug Administration for clearance, none has excited the widespread hopes of physicians and researchers like a machine called the Illumina MiSeqDx.
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REGENERATIVE MEDICINE


Revving the stem cell engine
Genetic Engineering and Biotechnology News
Like a car idling, not moving in any direction but ready to roll, stem cells may remain in their undifferentiated state, rumblingly pluripotent, and ready to become any type of mature cell. Pluripotent stem cells appear to have their engines tuned via Wnt signaling. But which Wnts and Wnt receptors are involved? Only recently, thanks to the work of researchers at the University of California, San Diego, have such details emerged.
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New stem cell study explains how breast cancer spreads
News-Medical.net
Breast cancer stem cells exist in two different states and each state plays a role in how cancer spreads, according to an international collaboration of researchers. Their finding sheds new light on the process that makes cancer a deadly disease. "The lethal part of cancer is its metastasis so understanding how metastasis occurs is critical," says senior study author Max S. Wicha, M.D., Distinguished Professor of Oncology and director of the University of Michigan Comprehensive Cancer Center.
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EMERGING MEDICAL TECHNOLOGIES


Information technology is changing healthcare system
The Washington Post
With the implementation of the Affordable Care Act, healthcare was a hot topic in 2013. Rising costs and continued challenges make certain healthcare will continue to be a big issue in 2014. Recently, Capital Business sat down with experts from the University of Maryland and the Arlington consultancy Evolent Health to talk about healthcare and the opportunities ahead for information technology to improve efficiency and quality of care.
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FEATURED ARTICLE
TRENDING ARTICLE
MOST POPULAR ARTICLE
Express yourself: Novel approach to study how genetic differences affect gene expression
ScienceDaily
Each individual carries a unique version of the human genome. Genetic differences can influence traits such as height, weight and vulnerability to disease, but precisely what these genetic variants are and how they exercise their impact is mostly unknown.

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Turning off 'aging genes'
ScienceDaily
Restricting calorie consumption is one of the few proven ways to combat aging. Though the underlying mechanism is unknown, calorie restriction has been shown to prolong lifespan in yeast, worms, flies, monkeys and, in some studies, humans.

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'Jumping genes' linked to schizophrenia
LiveScience
Some so-called jumping genes that copy and paste themselves throughout the genome may be linked to schizophrenia, new research suggests.

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MANAGED HEALTHCARE NEWS


Losing health insurance for 2014
CNNMoney
The Obama administration has fixed many of the problems that plagued the launch of Obamacare, but some Americans are finding themselves without coverage for the first time in years. Some say the new, more comprehensive plans on the exchange are simply unaffordable, while others are encountering technical problems that have prevented them from signing up.
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Healthcare website frustrates Spanish speakers
The Associated Press via Houston Chronicle
Mirroring problems with the federal healthcare website, people around the nation attempting to navigate the Spanish version have discovered their own set of difficulties. The site, CuidadoDeSalud.gov, launched more than two months late. A Web page with Spanish instructions linked users to an English form.
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Health industry expert offers Obamacare status report
Wall St. Cheat Sheet
It isn't only politicians and pundits who are making their opinions known about the Affordable Care Act — health industry experts are sharing their views on the healthcare law, as well. Robert Laszewski is the president of Health Policy and Strategy Associates Inc., a health consultancy that assists its clients understand changes in policy. Laszewski recently discussed the issues of Obamacare with the Washington Post's Ezra Klein.
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FDA: NEW TREATMENTS AND TECHNOLOGY


FDA OKs 2-drug combo treatment for advanced melanoma
HealthDay News
The drugs Mekinist and Tafinlar were approved for combination treatment of advanced melanoma skin cancer, the U.S. Food and Drug Administration announced. The two medicines "are the first drugs approved for combination treatment of melanoma," Dr. Richard Pazdur, director of the Office of Hematology and Oncology Products in the FDA's Center for Drug Evaluation and Research, said in an agency news release.
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FDA approves new drug for treatment of Type 2 diabetes
Medical News Today
The U.S. Food and Drug and Administration has announced the approval of a drug called Farxiga to help treat adults with Type 2 diabetes. The tablets, in combination with diet and exercise, are said to improve control of blood sugar levels. According to the American Diabetes Association, approximately 25.8 million people in the U.S. have diabetes. Type 2 diabetes accounts for around 90 percent of these cases.
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TRENDING ARTICLES
Missed last week's issue? See which articles your colleagues read most.

    8 tech predictions for medical practices in 2014 (Diagnostic Imaging)
Personalized medicine takes another step forward (OncLive)
J&J gambles $12.5M in rare big pharma bet on a stem cell therapy (FierceBiotech)
Newest-generation Bluetooth medical devices can disrupt healthcare (SearchHealthIT)

Don't be left behind. Click here to see what else you missed.


FAST FACTS
"Seizures can be caused by a number of factors, including epilepsy or fever, and most seizures stop themselves, according to the National Institutes of Health."


 

Genomics Biotech and Emerging Medical Technologies Institute eBrief
Colby Horton, Vice President of Publishing, 469.420.2635
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Natalie Rodriguez, Senior Content Editor, 469.420.2635   
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