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GENOMICS


Project sheds light on what drives genes
The New York Times
More than 200 scientists working on an ambitious federal project have begun to understand the complicated system of switches that regulates genes, turning some on and others off, making some glow brightly while others dim. They hope these discoveries, described in two dozen papers, will eventually lead to a deeper understanding of diseases and new ways to treat or cure them.
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Researchers: DNA rings may detect early cancer
Fox News
In a new study, researchers have shown that an innovative technique — the use of DNA microcircles — has the potential to detect a broad range of cancers in the earliest stages by forcing tumors to create a unique protein. The proof-of-principal study from Stanford University Medical School used DNA microcircles, a customized genetic construct consisting of tiny rings of DNA.
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SPONSORED CONTENT


Huge epigenomic map examines life's impact on our genes
New Scientist
The nature versus nurture debate is getting a facelift this week, with the publication of a genetic map that promises to tell us which bits of us are set in stone by our DNA, and which bits we can affect by how we live our lives. The new "epigenomic" map doesn't just look at genes, but also the instructions that govern them.
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Autism genes activate during fetal brain development
Business 2 Community
Adding to the growing body of evidence that autism begins before birth, researchers from the San Diego School of Medicine at the University of California have discovered that mutations that cause autism in children are connected to a pathway that regulates brain development.
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BIOTECH/DIAGNOSTICS/PERSONALIZED MEDICINE


Precision medicine to improve the risk and benefit of cancer care
JAMA
The past decade has seen important advances in the treatment of many cancers, with curative therapies for a few and extension of quantity and quality of life for others. For example, clarifying the role of both growth factor cell signaling and immunologic checkpoints in advanced melanoma has produced kinase inhibitors and immunotherapy drugs that each produce longer patient survival than any previous treatments.
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Personalized medicine: Great, but some really serious issues
Medscape
I am Art Caplan from the Division of Medical Ethics at the New York University Langone Medical Center. Did you hear about the big announcement from the White House and President Barack Obama? Precision medicine: The president has allocated a lot of money in his projected budget to advance the field of precision medicine.
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Precision medicine, personal genomics need industry standards
Health IT Analytics
Personalized genomic tests may be an integral part of the nation’s new focus on precision medicine, but patients who indulge their curiosity with cheap, at-home DNA tests may end up putting more pressure on providers instead of aiding their personal health management, claims a report from Frost & Sullivan.
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REGENERATIVE MEDICINE


Stem cell breakthrough opens door for 2-dad babies
Medical Daily
An international team of scientists have shown that it is possible to create human sperm and eggs from stem cells derived from adult skin, regardless of the donor’s gender. While this breakthrough could help men and women who have been rendered infertile by disease, gay groups have also expressed hope that this project will eventually lead to the creation of children made from same-sex parents.
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Europe approves Western world's 1st stem-cell therapy for rare eye condition
Reuters
Europe has approved the Western world's first medicine containing stem cells to treat a rare condition caused by burns to the eye, marking a milestone in the use of the technology. Holoclar, from privately held Italian company Chiesi, was given a marketing green light by the European Commission for treating so-called limbal stem cell deficiency due to physical or chemical burns.
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EMERGING MEDICAL TECHNOLOGIES


What is the state of wearable technology in healthcare?
mHealthIntelligence
While the wearable market is poised to expand, the impact on the healthcare landscape is up for debate. One of the biggest factors to the adoption of mobile device technology and wearable devices in the healthcare field is demand coming from patients.
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Mobile's impact on healthcare
Health IT Outcomes
A study published by the Economist Intelligence Unit has found mobile technology has the potential to profoundly reshape the healthcare industry, altering how care is delivered and received. Power To the Patient: How Mobile Technology is Transforming Healthcare surveyed 144 industry leaders in public and private healthcare, biotech, pharma, and medical devices to examine the impact of mobile technology across the international healthcare environment.
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ACCOUNTABLE CARE ORGANIZATIONS


CMS seeks comment on PCMH, care coordination, ACOs
Health IT Analytics
The Centers for Medicare and Medicaid Services is seeking public comment on its advanced primary care models intended to provide better care coordination, more personalized attention, and better overall population health management throughout the healthcare system.
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ACOs don't limit use of cardiovascular care
Health IT Outcomes
ACOs do not capitalize on savings opportunities, according to latest study. A study conducted by Dartmouth College and the University of Michigan researches has concluded the implementation of pilot accountable care organizations at 10 large health systems did not limit discretionary or non-discretionary cardiovascular treatment for patients.
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FDA: NEW TREATMENTS AND TECHNOLOGY


FDA reverses course on 23andMe DNA test in move to ease restrictions
The New York Times
The genetic testing company 23andMe took a step toward being able to offer consumers health-related information again, winning approval from the Food and Drug Administration for a test for mutations that cause a rare disease.
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FDA OKs new varicose vein treatment
HealthDay News via WebMD
A new system to permanently treat varicose veins in the legs by sealing the affected veins with adhesive was approved by the U.S. Food and Drug Administration. Many people with varicose veins experience no symptoms, while others have mild to moderate pain, blood clots, skin ulcers or other problems.
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MANAGED HEALTHCARE NEWS


Viable health information exchange not likely until 2017
By Scott E. Rupp
The results of a new survey show broad insight into the "tentative" progress that health information exchange and true interoperability have made. After polling nearly 2,000 health plan members and patients, 800 independent and employed physicians, 700 hospital executives, 1,200 insurers and 500 health information technology vendor staffers in a span of eight months, analysts have boiled down their findings thusly: "Persistent unpredictability describes the current state of operative HIEs."
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Health insurance confusion likely for many filing taxes
The Dallas Morning News
Taxpayers are just starting to learn the complex connection between the Affordable Care Act and taxes. For the first time, taxpayers will have to state whether they had health insurance through an employer, a health insurance exchange or a private insurance policy. If they didn’t, they could face a tax penalty.
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Disrespectful healthcare cultures and risks to patient care
By Christina Thielst
A recent PSQH article listed a dozen persistent medication safety gaffes that need to be resolved. Not surprisingly, No. 8 was "disrespectful behavior: a history of tolerance in healthcare." Disrespectful behavior includes bullying, threats, aggressiveness and even more passive forms such as ignoring and exclusion. These behaviors don't belong in any workplace, and certainly not in healthcare because of the risks created and the definite threat to patient safety. More than ever, teamwork and effective communication are needed in healthcare environments. Disrespect creates barriers to both of these.
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Genomics Biotech and Emerging Medical Technologies Institute eBrief
Colby Horton, Vice President of Publishing, 469.420.2635
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