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We wanted you to be aware that the FDA has granted accelerated approval of IBRANCE® (palbociclib) for the treatment of postmenopausal women with ER+/HER2- advanced breast cancer. Click here to see the press release!

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OAs part of APhA's longstanding and ongoing commitment to helping its members ensure optimal and safe patient use of prescription medications, nonprescription products, and dietary supplements, APhA convened national pharmacy and medicine leaders and other stakeholders on March 26. Click here for more information .

 

Fall Managed Care Forum: Register today!
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Register today for the 2015 Fall Forum being held November 12-13, 2015 at The Bellagio in Las Vegas. Click here to visit the conference website.
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GENOMICS


I got my genes tested, should you?
Popular Science
Alexandra Ossola writes: It takes me two subway rides, a 15-minute walk, one very large cup of coffee, and knocking on two incorrect office doors to arrive at the offices of the Program for Jewish Genetic Health in the Bronx, New York. I am there for a genetic screening designed to indicate which genes I could pass on to a potential child. And though I scheduled the appointment weeks ago, my circuitous arrival builds up the suspense — and my anxiety. Why am I doing this, I think to myself.
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Does this make me fat, or is it my genes?
MedPage Today
Picking a fight with your spouse is like scratching a scab — it's rarely a good idea, and it's worse when done in public. But that didn't stop one couple from getting into an argument during a session at the American Diabetes Association annual meeting. People within earshot of the couple, glasses of Chianti and Pinot grigio in hand, listened closely as the husband laid out the terms of the argument. Who were the so-called opponents? Jeffrey Flier, M.D. — the dean of the faculty of medicine at Harvard University in Boston, and his wife, Eleftheria Maratos-Flier, M.D., a professor of medicine at Harvard. Their topic was the root cause of the obesity epidemic.
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SPONSORED CONTENT


Researchers discover new aspect of gene regulation
News-Medical.net
Researchers at the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna as well as at the University of Natural Resources and Life Sciences in Vienna have discovered an entirely new aspect of gene regulation they call exitron splicing. Their findings, recently published in the renowned scientific journal Genome Research, will help to explore the adaptive evolution of gene regulation. Furthermore, the discovery sets a basis for the development of cancer biomarkers and therapeutic targets.
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BIOTECH/DIAGNOSTICS/PERSONALIZED MEDICINE


Mobile data collection's role in precision medicine and the clinical trial of the future
mobihealthnews
In 2011, Pfizer announced a novel clinical trial that would be fully remote, with every aspect of the trial being handled either online, over the phone, or by mail. But that trial was cancelled due to a failure to recruit enough participants, and a promised mulligan never emerged.
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Personalized schizophrenia treatment on the way?
Medscape
Although schizophrenia patients with the 22q11.2 gene deletion respond to clozapineat a lower dose than other patients, they experience more serious adverse events, say Canadian researchers in findings that may pave the way for personalized medicine in this difficult-to-treat patient population.
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REGENERATIVE MEDICINE


Scientists discover way to disrupt brain tumor regeneration
Medical News Today
Some brain tumors are difficult to get rid of and often regenerate following treatment. A group of researchers, however, have identified a way in which brain tumor stem cells — the key to this regeneration — can be disrupted, potentially halting the spread of aggressive cancer.
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New research shows that stem cells are sensitive to oxygen radicals and antioxidants
News-Medical.net
Stem cells are especially sensitive to oxygen radicals and antioxidants shows new research from the group of Anu Wartiovaara in the Molecular Neurology Research Program of University of Helsinki. The research led by researcher Riikka Martikainen was published in Cell Reports.
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EMERGING MEDICAL TECHNOLOGIES


Will the Apple Watch revolutionize healthcare?
Medscape
Wearable technology — or "wearables" — are electronic technologies incorporated into items of clothing or worn as accessories. Today, wearables are increasingly used to collect and transmit health or fitness data directly from the user's body. As most of us can attest, our smartphone has become so much a part of us that it might be considered by some to be a wearable. One study even showed that 90 percent of adults 18-29 years of age sleep with their smartphones.
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High-tech monitors, cool gadgets help spark a healthcare revolution
USA Today
As the world becomes more digitized, the healthcare industry is racing to keep up, sparking an explosion of new digital technology geared to improving patient care. Most visible to patients is the move to electronic medical records, or EHRs, by doctors and hospitals in an effort to streamline record-keeping and meet federal guidelines.
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ACCOUNTABLE CARE ORGANIZATIONS


Little progress in waiving ACO telehealth restrictions
Health Data Management
The American Telemedicine Association is upset with the Centers for Medicare and Medicaid Services’ final rule on accountable care organizations, which ATA says “severely restricts” the use of telemedicine services which could benefit millions of Americans. CMS released a final rule updating the Medicare Shared Savings Program to give providers greater flexibility and grow participation in the program.
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California's ACOs: A model for the nation?
FierceHealthcare
California's successful accountable care organizations could offer valuable lessons for rest of the nation, which has seen mixed results with ACOs, according to California Healthline. The Golden State has more than 100 ACOs, according to the article, representing nearly 1 in 7 ACOs nationwide.
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FDA: NEW TREATMENTS AND TECHNOLOGY


GlaxoSmithKline's new asthma drug gets a split vote from FDA advisers
FierceBiotech
A group of FDA advisers backed GlaxoSmithKline's latest asthma treatment for use in adults but balked at recommending it for adolescents, setting the stage for a likely approval in the fall. GSK's injection, mepolizumab, works by blocking the protein interleukin-5 to prevent buildups of white blood cells in the lungs that can exacerbate asthma.
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FDA panel backs Amgen's cholesterol-lowering drug
The Wall Street Journal
A Food and Drug Administration advisory committee recommended that the agency approve Amgen Inc.’s cholesterol-lowering drug Repatha, the second in a class of promising heart medicines that could change medical practice and generate billions of dollars in sales.
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MANAGED HEALTHCARE NEWS


Saving affordable health insurance
The New York Times
The Affordable Care Act, which has helped millions of people get healthcare, is now fully woven into the nation’s social fabric. As President Barack Obama said, there is something “deeply cynical about the ceaseless, endless, partisan attempts” to roll back the progress already made. His remarks at a forum of the Catholic Health Association come only weeks before the Supreme Court is expected to issue a ruling that could, if the administration loses, eliminate federal tax subsidies in 34 states that have made it possible for millions of Americans to buy health insurance.
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Health insurance premiums will go up in 2016, but by how much?
NPR
Some health insurance companies are asking for big price increases next year, and that has again riled critics of the federal healthcare law. But early analysis shows those steep hikes may not affect the majority of consumers. The numbers released came out of a June 1 deadline, under the Affordable Care Act, that requires insurance companies to tell government regulators when they're requesting price hikes of more than 10 percent.
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TRENDING ARTICLES
Missed last week's issue? See which articles your colleagues read most.

    Do creativity and schizophrenia share a small genetic link? Maybe (NPR)
Explaining 'epigenetics': The health buzzword you need to know (TIME)
Genes do influence when you have your firstborn (Inquisitr)
In the future, treatments tailored to patients (The Boston Globe)
Bundled payments may be more cost effective than ACOs (FierceHealthFinance)

Don't be left behind. Click here to see what else you missed.
 

Genomics Biotech and Emerging Medical Technologies Institute eBrief
Colby Horton, Vice President of Publishing, 469.420.2635
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Natalie Rodriguez, Senior Content Editor, 469.420.2635   
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