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Check out JMCM’s new website at www.jmcmpub.org

Seattle Genetics Announces FDA Regular Approval of ADCETRIS® for Classical Hodgkin Lymphoma Patients at High Risk of Relapse or Progression. Click here to view more information.

We wanted you to be aware that the FDA has granted accelerated approval of IBRANCE® (palbociclib) for the treatment of postmenopausal women with ER+/HER2- advanced breast cancer. Click here to see the press release!

Otezla® (apremilast) is approved for the treatment of patients with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy. Please click here for more information.

OAs part of APhA's longstanding and ongoing commitment to helping its members ensure optimal and safe patient use of prescription medications, nonprescription products, and dietary supplements, APhA convened national pharmacy and medicine leaders and other stakeholders on March 26. Click here for more information .

 



Fall Managed Care Forum: Register today!
NAMCP

Register today for the 2015 Fall Forum being held November 12-13, 2015 at The Bellagio in Las Vegas. Click here to visit the conference website.
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GENOMICS


Circadian genes go to sleep every day at the periphery of the nucleus
Phys.org
Mobility between different physical environments in the cell nucleus regulates the daily oscillations in the activity of genes that are controlled by the internal biological clock, according to a study that is published in the journal Molecular Cell. Eventually, these findings may lead to novel therapeutic strategies for the treatment of diseases linked with disrupted circadian rhythm.
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Low vitamin D genes linked to MS
BBC
The findings, based on the DNA profiles of tens of thousands of people of European descent, add weight to the theory that the sunshine vitamin plays a role in multiple sclerosis. Scientists are already testing whether giving people extra vitamin D might prevent or ease MS. Experts say the jury is still out.
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What if doctors could heal broken genes?
LiveScience
Science is about asking questions. Sixty years ago, the key question in biology was, "What does the human genetic code look like?" That was followed by, "How many genes make up human DNA?" which itself led to, "Which genes cause diseases?" Now the question is, "What if doctors could repair broken genes?"
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BIOTECH/DIAGNOSTICS/PERSONALIZED MEDICINE


Mobile apps and personalized medicine, making life for primary care providers even more frustrating
iMedicalApps
“Personalized care through mobile health technologies inspires the transition from isolated snapshots based on serial visits [to clinicians] to real time and trended data” according to Ryan J. Shaw, Ph.D., RN, and his associates at Duke University. In an editorial in the American Journal of Medicine, Shaw et al point out that most primary care is episodic, with physicians only seeing a tiny sliver of a patient’s behavior and health-related information.
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How clinical registries advance personalized medicine
FierceHealthIT
Projects funded through the Agency for Healthcare Research and Quality are harnessing big data to answer questions such as the best knee replacement for a particular patient and how to effectively treat a child's inflammatory bowel disease, according to a new issue brief. The brief focuses on how patient registries can help providers make decisions about particular patients sitting before them.
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REGENERATIVE MEDICINE


Companies offer athletes hope with questionable stem cell treatments
USA Today
For a minimum price of $15,000, several professional athletes recently received a curious new medical treatment in New York. It’s called “The Soup” — a mixture of human cells that includes stem cells derived from a patient’s own fat. If it works the way they hope, The Soup can help repair injuries that otherwise might require surgery — damaged knees, elbows, hips, necks and more.
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Asterias's stem cell therapy shows promise in study
Reuters
Asterias Biotherapeutics Inc. said initial data from a small study showed that its lead stem cell therapy could improve mobility in patients paralyzed by a spinal cord injury. The company's shares were up 25 percent at $5.26 in mid-day trading on heavy volumes. Shares of BioTime Inc., a company that owns nearly 70 percent of Asterias, were little changed at $3.07.
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  Getting Patients Back to Better

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EMERGING MEDICAL TECHNOLOGIES


Report: Telehealth will have strong impact on home health by 2020
By Scott E. Rupp
A new report suggests the market for home health technology will see strong growth, and telehealth will have an "impact on nearly every aspect of the healthcare ecosystem." Thus, the global market for home health technologies will grow from somewhere around $3.4 billion in 2014 to more than $13 billion by 2020. Remote medical consultations will constitute the largest portion of this revenue mix, followed by eldercare, medical monitoring, and health and wellness devices.
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ACCOUNTABLE CARE ORGANIZATIONS


Few Medicare ACOs earned bonuses in 2014
Modern Healthcare
Three out of four Medicare accountable care organizations did not slow health spending enough to earn bonuses last year, a continuation of mixed results for an initiative that federal officials have targeted for rapid expansion. Medicare released 2014 results for 353 accountable care organizations, which include hospitals and physician groups that agreed to meet targets for quality and slow spending.
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Primary care docs reaping the most from shared-savings ACOs
Modern Healthcare
For the second year, the CMS has awarded bonuses to 1 in 4 accountable care organizations working under a Medicare model intended to spur providers to deliver lower-cost care. They will share $422 million out of the $833 million they collectively saved the government in 2014. ACO networks get to decide for themselves how to distribute the money, and primary-care doctors appear to be benefiting the most, according to a review of disclosures by ACOs participating in Medicare's Shared Savings Program.
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FDA: NEW TREATMENTS AND TECHNOLOGY


FDA warns of severe joint pain risk with DPP-4 diabetes drugs
Reuters via Fox News
A class of diabetes drugs that include Merck & Co Inc's Januvia has been linked with severe joint pain, the U.S. Food and Drug Administration said. The FDA said it had identified 33 cases of severe joint pain in patients taking a class of drugs known as DPP-4 inhibitors between Oct. 16, 2006, when the first one was approved, through Dec. 31, 2013.
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FDA oversight on high-risk apps in mobile health industry
mHealthIntelligence
As the mobile health industry continues to progress and new innovations impact patient care, regulatory agencies are taking part in greater oversight of m-health apps, wearable devices, and remote monitoring tools. From ensuring mobile apps are safe for use among patients to developing new reimbursement policies for healthcare providers offering telemedicine services, federal agencies are driving forward patient engagement and security in the mobile health industry.
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MANAGED HEALTHCARE NEWS


The problem with GOP plans to sell health insurance across state lines
The New York Times
At the Fox News Republican debate, Donald Trump offered a way to lower healthcare costs: Allow insurers to sell their policies across state lines. “What I’d like to see is a private system without the artificial lines around every state,” he said. “I have a big company with thousands and thousands of employees. And if I’m negotiating in New York or in New Jersey or in California, I have like one bidder. Nobody can bid.” Erasing those lines, he said, would result in “great plans.”
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What happens when you can't afford your health insurance
U.S. News & World Report
Getting health insurance is one thing; paying premiums month after month to keep it is another. If you have health insurance through your job, your premium comes out of your paycheck automatically, and unless you have a qualifying life event — like marriage — you're stuck with that policy until open enrollment.
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The importance of evidence-based practice
By Dr. Abimbola Farinde
Researchers, healthcare providers and health policy advocates still continue to debate what specifically defines evidence-based practice. They argue over the merits of the evidence for various interventions and how the evidence is utilized and integrated. Yet the fact still remains that the implementation of evidence-based practice measures is becoming a widely-recognized topic because it focuses on how research findings can appropriately be applied to clinical practice.
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TRENDING ARTICLES
Missed last week's issue? See which articles your colleagues read most.

    A fat-burning gene may help weight loss (TIME)
Holocaust survivors' trauma lives on in kids' genes (USA Today)
Personalized medicine holds promise for cancer patients (CBS News)
The FDA is basically approving everything — here's the data to prove it (Forbes)
Do physicians really hate their EHRs? (By Scott Rupp)

Don't be left behind. Click here to see what else you missed.
 

Genomics Biotech and Emerging Medical Technologies Institute eBrief
Colby Horton, Vice President of Publishing, 469.420.2635
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Natalie Rodriguez, Senior Content Editor, 469.420.2635   
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