Under the Microscope
Mar. 14, 2012

A new way to look at tissue biopsies
Dark Daily
Reading tissue biopsies with a new stain-free method could eventually help pathologists achieve faster and less subjective cancer detection. Should the technology prove viable, it would displace many of the longstanding tissue preparation methodologies used today in the histopathology laboratory.More

Avoiding dementia similar to heart disease — lifestyle changes key
Late-life dementia has a lot in common with heart disease, and many of the same causes, according to an article in Nature Reviews Neurology. Like heart disease, the cognitive impairment that accompanies aging is usually the result of a combination of lifestyle and other factors. Diabetes, obesity, untreated hypertension, sedentary lifestyle and stress are all linked to both heart disease and dementia.More

Raising a glass a day to lower stroke risk in women
A study offers good news for women who unwind with a cocktail at the end of the day: Light to moderate drinking is associated with lower stroke risk. The report involved 26 years of data on 83,578 women who were part of the long-running Nurses' Health Study — a study of how factors like diet and alcohol consumption may influence women's long-term health.More

A 'thank you' to histotech professionals
VideoBriefJared Schwartz, Chief Medical Officer of Aperio and 2009 NSH Culling Memorial lecture award winner, recognizes the importance of histotechs to the future of pathology and appreciates everything that histotechnology professionals do.More

In tests, bone cells aid kidney recipients
The Associated Press via Arizona Daily Star
An experimental technique seems to be freeing some kidney-transplant patients from taking anti-rejection drugs. Researchers transplanted certain cells from the kidney donor's bone marrow along with the new organ. Five of eight transplant recipients were off immune-suppressing medication up to 2 1/2 years later, researchers said. More

Add spice to cut high-fat meal, reduce heart disease risk
VideoBriefNo need to be stingy with spices. Research from Penn State finds heavily spiced meals may do the heart good. The study found a spicy meal helps cut levels of triglycerides, a type of fat, in the blood — even when the meal is rich in oily sauces and high in fat.More

Study reveals how proteins begin DNA replication
R&D Magazine
Before any cell can divide, it has to replicate its DNA. Scientists who want to know how normal cells work are keen to understand this process. As a step toward that goal, scientists have deciphered molecular-level details of the complex choreography by which intricate cellular proteins recognize and bind to DNA to start the replication process.More

Tips for reducing hospital readmissions for heart failure patients
Becker's Hospital Review
Under healthcare reform, hospitals may face financial penalties for preventable readmissions. Reducing readmissions can thus save hospitals money, improve patient care and create efficiencies. Michigan-based Spectrum Health developed a program to prevent readmissions. Its heart failure team focused on follow-up visits, transitions of care and an observation unit to keep heart failure patients at home after discharge. More

Protein discovery could switch off cardiovascular disease
Bioscience Technology
Researchers have found a protein inside blood vessels with an ability to protect the body from substances which cause cardiovascular disease. The findings have revealed the protein pregnane X receptor can switch on different protective pathways in the blood vessels.More

Computation dramatically improves resolution of electron microscopy
Transmission electron microscopy relies on electronic lenses that focus the signal much like their optical brothers. And like in optical microscopy, the lenses themselves present challenges and barriers to achieving higher resolution imaging. Now researchers have demonstrated a method, electron ptychography, that does away with the lenses and uses computers to reconstruct the unfocused signal.More

Overweight physicians often miss overweight in patients
Medical News Today
According to a study conducted by researchers at Johns Hopkins, overweight doctors are significantly less likely to identify patients' weight problems in their diagnoses. Lifestyle factors considerably increase the risk of developing cancer, diabetes, cardiovascular disease, as well as the majority of major diseases. More