Under the Microscope
Nov. 12, 2014

Submit a Workshop Abstract for the 41st Annual Symposium/Convention
The NSH Convention Program Team invites you to submit an abstract for the 2015 NSH Symposium/Convention. This year a new track of 60-minute troubleshooting workshops will be available as well as the 90-minute and three-hour workshops. A variety of topics are welcomed and we encourage both clinical and non-clinical histology professionals to participate. Click here for a list of topics requested in evaluations. Submit your abstract for consideration today!More

NSH call for volunteers
Newly appointed committee chairs are excited to start their projects for 2015 and need your help! If you are looking for a great way to get involved, this is a great place to start. Plus, volunteering gives you two contact hours per year. To volunteer for committees, visit the business or resource committee Web pages and email the committee chair to get involved. We look forward to your help in reaching the goals of our new strategic plan.More

NSH membership renewals
It's about that time of year again! Keep a look out for NSH membership renewals coming to you next week. We appreciate you being a part of our organization and hope you will continue to support us in reaching our histology educational goals.More

LabCorp spends $5.6 billion to acquire Covance, challenging Quest Diagnostics for position as largest US diagnostics company
Dark Daily
With clinical laboratory acquisition candidates dwindling in number, Laboratory Corporation of America Holdings looked outside the medical laboratory industry and agreed to acquire Covance Inc., a major player in clinical trials testing, for approximately $6.1 billion in cash and stock. By taking this action, LabCorp will have bragging rights as the world's largest laboratory testing company.More

Human clinical trials to begin on drug that reverses diabetes in animal models
A study at the University of Alabama at Birmingham has shown that verapamil, a drug widely used to treat high blood pressure, irregular heartbeat and migraine headaches, is able to completely reverse diabetes in animal models. The UAB team will now move onto clinical trials to see if the same results are repeated in humans. Following years of research, the UAB researchers have shown that high blood sugar causes the body to overproduce a protein called TXNIP. Too much of this protein in specialized cells in the pancreas called beta cells contributes to the progression of diabetes by leading to the death of the cells and countering the body's efforts to produce insulin.More

Medical experts look for new ways to test Ebola drugs
Medical experts are meeting at the World Health Organization in Geneva to figure out how to test potential Ebola drugs in Africa. In addition to determining which experimental drugs should be the highest priority, the experts are sorting through some difficult ethical issues. In short, they're trying to figure out how to design tests that will provide the fastest and most trustworthy answers — and yet minimize the need for comparison groups who won't be offered the experimental treatments.More

Nanodaisies can kill cancer
Laboratory Equipment
VideoBriefNC State researchers have developed a potential new weapon in the fight against cancer: a daisy-shaped drug carrier that's many thousands of times smaller than the period at the end of this sentence. Once injected into the bloodstream, millions of these nanodaisies sneak inside cancer cells and release a cocktail of drugs to destroy them from within. The approach is more precise than conventional methods, and it may also prove more effective. By ensuring anti-cancer drugs reach their target in controlled, coordinated doses, nanodaisies could cut down on the side effects of traditional chemotherapy.More

Single molecular switch may contribute to major aging-related diseases
Medical Xpress
A study led by Massachusetts General Hospital investigators has identified what appears to be a molecular switch controlling inflammatory processes involved in conditions ranging from muscle atrophy to Alzheimer's disease. In their report published in Science Signaling, the research team found that the action of the signaling molecule nitric oxide on the regulatory protein SIRT1 is required for the induction of inflammation and cell death in cellular and animal models of several aging-related disorders.More

Surprising sameness among E. coli strains raises hopes for global vaccine
Genetic Engineering & Biotechnology News
While surveilling the worldwide spread and evolution of a deadly bacterium, researchers at the Wellcome Trust Sanger Institute uncovered a surprising vulnerability. The bacterium, enterotoxigenic Escherichia coli, differs from strain to strain much less than had been expected. In particular, it turns out that strains from relatively poor countries around the world — Latin America, Africa, and Asia — have a limited repertoire of colonization factors, surface proteins that enable the bacteria to attach to human stomach lining. The lethal bacterium had been feared to vary widely across the world, but a new large-scale study suggests that many of the bacterium’s strains spread globally from a common source. As a result, there may be commonalities among ECTC strains that make it possible to target multiple strains with a single vaccine.More

California Clinical Laboratory Association's annual conference showcases medical labs using EMPIs and similar technologies to deliver more value
Dark Daily
More than 100 clinical laboratory owners and lab executives gathered recently for the annual meeting of the California Clinical Laboratory Association. Because the medical laboratory testing marketplace in California is often a bellwether for trends that go national, the presentations were timely and of universal interest to lab professionals working in other regions of the United States. The membership of CCLA certainly reflects the broader changes happening in the clinical laboratory industry nationally. More

Patient access to pathology results
The ability for patients to access their pathology results through a patient portal or potentially through Australia's PCEHR has been a topic of intense discussion over the last year or so. However, the evidence for the efficacy of this approach has been mixed. In this article, ACHI's Program Evaluation Subcommittee provides a targeted literature review of research and articles published between July 1, 2013, and June 30, 2014, as part of ACHI's biannual evidence review.More

Biomarker test could help reduce unnecessary antibiotic prescribing
The Pharmaceutical Journal
Point-of-care testing for a biomarker of bacterial infection would help to limit unnecessary antibiotic prescribing by GPs, suggests a systematic review. Data from six randomized trials assessing C-reactive protein testing in patients with acute respiratory infection indicated that antibiotic use was lower among patients who were tested than in those who were not.More

Drug may boost vaccine efficacy in the elderly
Laboratory Equipment
Oxford University scientists have developed a new method of boosting the aging immune system using a naturally occurring chemical compound. Early tests in mice carried out by the research team have shown that the compound restores the immune system's inbuilt "memory," enabling the body to mount a more powerful protective immune response following vaccination.More