Eye on SGi
Feb. 22, 2012

Embryos starved of oxygen may be 'programmed' for heart disease
Heart disease has long been ranked the No. 1 cause of death globally. Known as the silent killer, it stalks its prey from conception through adulthood, often striking without warning. A new study suggests that one risk factor may begin even before birth, showing how low oxygen in the womb — or fetal hypoxia — can impair the heart later in life. Fetal hypoxia can be caused by a variety of factors. Mothers who live at high altitude, smoke, or develop diabetes during pregnancy can starve their embryos of oxygen.More

Surgeons place pacemaker in 15-minute-old newborn
The Associated Press via WTOP-FM
The name Jaya in Hindi means victorious. And little Jaya Maharaj was just that, when she became one of the smallest recipients of a pacemaker when she was just 15 minutes old. A team of doctors at Stanford University's Lucile Packard Children's Hospital determined the girl born nine weeks premature only had hours to live if they did not perform the surgery. Jaya, who was diagnosed in the womb with a severe heart ailment, entered the world with a heart rate of 45 beats per minute. A health newborn heartbeat is 120 to 150 beats per minute.More

Blood thinners may help treat ovarian cancer
Los Angeles Times
As many as one-third of women with ovarian cancer have high levels of platelets in their blood, which is linked to worse outcomes, researchers reported. Platelets are components of cells that clump together to stop bleeding. Having an excessively high level of platelets is called thrombocytosis. Doctors have long known that thrombocytosis is associated with cancer. In the new study, published in the New England Journal of Medicine, researchers at M.D. Anderson Cancer Center in Houston analyzed data from 619 women with ovarian cancer. More

Study: Pre-eclampsia 'leads to higher heart disease risk'
The Telegraph
Women diagnosed with pre-eclampsia when pregnant are at a higher risk of heart disease later in life, a study indicates. They are almost a third more likely (31 percent) to be at risk of cardiovascular disease by the time they are 48 years old, than those who did not suffer from the condition in pregnancy, according to a British study of nearly 3,500 women. The study, carried out by researchers at the School of Social and Community Medicine at Bristol University, is published in Circulation: Journal of the American Heart Association.More

Expectant management 'preferred' in acute postpartum anemia
International Federation of Gynecology and Obstetrics
Foregoing a blood transfusion is the better option for women with acute postpartum anemia, maternal and newborn health researchers have argued. A study by a team in the Netherlands showed there is a statistically significant decrease in the severe physical fatigue associated with this condition — which is the result of excessive blood loss during labor — when mothers are given a transfusion. However, the scientists said expectant management is preferred over this procedure because the difference in outcomes is small.More

Research: Aspirin shows promise in limiting cancer for women who have HIV
The New York Times
Aspirin should be evaluated for its potential to prevent cervical cancer in women infected with HIV, say scientists who recently reported a connection between the virus and inflammation of cervical tissue. Their study, published in the journal Cancer Prevention Research, found that the virus that causes AIDS also drives up production of a prostaglandin called PGE2 in cervical tissue. PGE2 is linked to inflammation and the development of tumors.More

Lupus, rheumatoid arthritis linked to fertility woes, miscarriage
HealthDay News via MSN
Women with rheumatoid arthritis or systemic lupus erythematosus often have fewer children than they'd hoped for, according to a new study. These autoimmune diseases, which typically develop during women's reproductive years, cause fertility problems and miscarriage, researchers said. For the study, researchers asked 578 women with rheumatoid arthritis and 114 women with lupus about their reproductive health, and divided them into three groups according to how their condition affected their desire and ability to have children.More

Normal breast protein linked to cancer development
Doctors Lounge
Trefoil protein, which maintains the integrity of the epithelial surface in the normal breast, is highly expressed in well-differentiated tumors, correlating with low histological grade, and also has an expression profile which is consistent with a role in breast cancer progression and metastasis, according to a study published in the March issue of The American Journal of Pathology. Noting that TFF3 is known to stimulate invasion and angiogenesis in vitro, Ahmed R.H. Ahmed, from the University of Newcastle upon Tyne in the United Kingdom, and colleagues examined the expression of TFF3 in 34 normal breast tissue samples, 86 benign breast lesions, 106 in situ breast lesions, and 266 malignant breast lesions.More

Research: 'Infertile' women may just need longer to conceive
Medical Xpress
One-in-four women with a history of infertility can still end up having a baby without treatment, a new study from The University of Queensland shows. The study, led by Dr. Danielle Herbert from the School of Population Health and Centre for Clinical Research, reveals that women who have been clinically diagnosed as infertile after 12 months of unsuccessfully trying for a baby may actually just need longer to conceive. "Many women aged up to 36 years with a history of infertility, especially those who have already had a baby, can achieve spontaneous conception and live birth without using fertility treatment indicating they are sub-fertile rather than infertile," Herbert said.More