SGI Annual Scientific Meeting — March 21-24
Final Program — Update
2012 SGI Meeting Registration Form
2012 SGI Meeting at a Glance
Registration and Hotel Accommodation for San Diego:
SGI meeting registration: For those of you who have not registered for the 2012 annual meeting, online registration will remain open through March 24. You also can register on-site.
Hotel Accommodation: The SGI Group rates have expired at the Manchester Grand Hyatt Hotel. You still may be able to get rooms; however, SGI Group rates will not be offered. The program outline is available through the link to the SGI website. We look forward to seeing you in San Diego for what promises to be a truly outstanding meeting.
Hold the Presses — New Speakers Confirmed for SGI Summit
Society for Gynecologic Investigation Summit 2012
Prematurity and Stillbirth
Antecedents, Mechanisms and Sequelae
Brisbane Convention & Exhibit Centre
Professor John Challis: University professor emeritus, University of Toronto; adjunct professor, University of Western Australia; past president SGI.
Professor Sir Peter Gluckman: Chief science adviser to the prime minister of New Zealand.
Professor Mark A. Hanson: Director, Academic Unit of Human Development & Health; director, Institute of Developmental Sciences; professor of cardiovascular sciences, British Heart Foundation; faculty of medicine, University of Southhampton, United Kingdom.
Professor Alan H. Jobe: Professor of Pediatrics/Neonatology, Cincinnati Childrens Hospital, Cincinnati, Ohio.
Professor Stephen Lye: Vice-chair, research and professor of obstetrics and gynecology at the University of Toronto; co-chair of the Centre for Women's and Infant's Health at Mount Sinai Hospital, Toronto; president, SGI.
Professor John Mattick: Executive director, Garvan Institute.
Professor Leslie Myatt: Professor of obstetrics and gynecology, co-director Center for Pregnancy and Newborn Research, University of Texas Health Science Center, San Antonio; past president, SGI.
Professor Gordon C.S. Smith: Head of department, Department of Obstetrics and Gynaecology, Cambridge University, Cambridge, United Kingdom.
SGI SUMMIT TURKEY 2012
Innovations in Obstetrics and Gynecology
Harbiye Military Museum and Culture Center
For women, fibroids linked to gene mutation
University of Pittsburgh via Futurity
Mutations in a regulatory gene are present in two-thirds of uterine fibroids, a finding that sheds light on the pathways that allow the noncancerous tumors to develop. Fibroids — that can cause heavy bleeding, anemia, pain, and infertility — affect a quarter of all women, and are the most common cause of hysterectomy in the United States. "Medical therapies for fibroids have had little success because we don't really understand how or why they develop," says Aleksandar Rajkovic, assistant professor of obstetrics, gynecology, and reproductive services at the University of Pittsburgh. "Our first step to unraveling this process was to determine if there are differences between the genes of fibroid cells and those of the neighboring normal tissue."
Cadmium in diet is linked to higher breast cancer risk
Los Angeles Times
In a finding that strengthens the link between environmental pollutants and rising rates of breast cancer, new research finds that women whose diets contain higher levels of cadmium are at greater risk of developing breast cancer than those who ingest less of the industrial chemical in their food. Cadmium, a heavy metal long identified as a carcinogen, leaches into crops from fertilizers and when rainfall or sewage sludge deposit it onto farmland. Whole grains, potatoes, other vegetables and shellfish are key dietary sources of cadmium, which also becomes airborne as a pollutant when fossil fuels are burned, and is likely inhaled as well as ingested.
Meth use in pregnancy may lead to behavioral problems in children
The first study to look at methamphetamine's potential lasting effects on children whose mothers used it in pregnancy finds these children at higher risk for behavior problems than other children. The behavior differences — anxiety, depression, moodiness — weren't huge, but lead researcher Linda LaGasse called them "very worrisome."
New cervical cancer screening guidelines include HPV tests
Although infection with human papillomavirus is the leading cause of cervical cancer, until now, an influential government group has been reluctant to recommend using the HPV test to screen for the disease. That changed when the U.S. Preventive Services Task Force recommended that the HPV test is appropriate for some women as part of routine cervical-cancer screening. The task force had previously said, in draft guidelines released in October, that there wasn't enough evidence to recommend the HPV test, but the new recommendations are based on a review of the most recent scientific studies, which find that HPV tests can reliably detect cervical cancer and spare lives.
Research leads to advances in ovarian cancer
Irish Medical Times
Ovarian cancer is the most deadly of the gynecological cancers and approximately 140,000 women worldwide die from the disease each year. According to the National Cancer Registry, approximately 315 new cases of ovarian cancer are diagnosed in Ireland every year and 269 women die from the disease in a setting in which there have been few advances in the last decade. However, recent developments in ovarian cancer have improved the prognosis for patients. "The unfortunate reality is that ovarian cancer has usually spread beyond the ovary even before the diagnosis is made, so the prognosis is poor. There's no routine screening available, such as there is for cervical or possibly breast cancer," said Prof Stan Kaye, Consultant Medical Oncologist at the U.K.'s Royal Marsden Hospital.
News from Reproductive Sciences
Importance of Vaginal Microbes in Reproductive Health
Reproductive Sciences, March 2012
The authors write that more than 250 species of bacteria have been detected in the vagina using genomic sequencing. Lactobacillus iners and L crispatus dominate in most women who have a clinically healthy status. Unfortunately, the abundance profiles can change dramatically with significant increases in pathogens associated with bacterial vaginosis and aerobic vaginitis. The BV microbiota have at least four different abundance profiles, indicating this is a complex condition, yet one that is treated with essentially two antimicrobial agents which never were designed for eradicting these organisms in dense biofilms. Future studies will uncover which abundance profiles are particularly associated with a risk of preterm labor, and it is hoped that they can identify the mechanisms involved in the switch from healthy to a BV or AV state. MORE.
A rare disease in the smallest of patients
Haleigh Jacobs and her husband, David, have spent the last two months in the hospital, hovering over their 8-pound newborn, Brantley. He has yet to spend a day outside the incubator, smell fresh air or go home to meet his siblings. Brantley's right leg juts out like a reddish brown lump of flesh that is thicker than his torso. His toes, indistinguishable from each other, look like dimples. The leg is studded with damaged blood vessels, veins and capillaries that look like raisins. Another lump protrudes from his abdomen. The diagnosis: Klippel-Trenaunay syndrome, a rare disorder that appears in one in 100,000 children. His doctors said that eventually, he will have to have his leg amputated.
Too much exercise delays pregnancy in normal-weight women
HealthDay News via WBRC-TV
Exercise is a plus for women trying to become pregnant, but overdoing workouts might make it harder to conceive — unless you're overweight, researchers report. Usually a risk factor for most health problems, being overweight or obese didn't hinder fertility in heavy women who logged vigorous workouts — running, fast cycling and aerobics. However, healthy-weight women who performed more intense workouts more likely were to experience delays becoming pregnant. The study was led by U.S. and Danish researchers who tracked physical activity and fertility in thousands of Danish women.
Melissa Healy: Menopause fog? It's real, but not what you think
Los Angeles Times
A new study published in the journal Menopause makes a start at finding answers to questions and cognitive complaints that women have had for years, and leaves many more still to be explored. It finds that when menopausal women complain of memory problems, they are most likely having trouble with two specific cognitive skills: maintaining their focus — especially on tasks that are complex or tedious — and holding short bits of information, say, a telephone number or a shopping list, in memory for less than a few minutes.