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Ovarian cancer drug trebananib fails to improve overall survival
Reuters
Amgen Inc. said its experimental ovarian cancer drug did not show statistically significant improvement in overall survival rate in a late-stage trial. Patients given the drug, trebananib, along with a chemotherapy agent paclitaxel, experienced overall survival of 19.3 months, compared with 18.3 months for the placebo group. Statistically significant improvement in overall survival was the secondary goal of the trial.
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SGO NEWS


Annual Meeting early bird registration now open
Early bird registration for SGO’s 2015 Annual Meeting on Women’s Cancer is open until Monday, Jan. 26, 2015. Member/non-member fees and online registration are available on the SGO website. SGO Chicago-based members and staff have extended a special video invitation to all SGO members to “See You in Chicago” March 28-31.
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SURVIVORSHIP


Kidney condition adds morbidity in cervical cancer
Cancer Network
Hydronephrosis is associated with substantial morbidity in patients with cervical cancer, and is potentially associated with poorer survival as well, according to a new study published in Supportive Care in Cancer. Hydronephrosis, essentially a swelling of the kidney, develops when a blockage in the renal collecting system results in distention of renal calyces. “Women with cervical cancer often develop this complication as a result of tumor or lymph node encroachment, inflammation, or scarring at the pelvic rim,” wrote study authors led by Aminah Jatoi, MD, of the Mayo Clinic in Rochester, Minnesota. Stent placement or urinary diversion procedures are often used as treatment for the complication.
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PREVENTION


Education program helps with side effects of ovary removal for cancer prevention
Oncology Nurse Advisor
More women are having ovary-removing surgery as a cancer prevention measure, but many are often unaware of sexual or psychological side effects of the procedure. A new study shows a half-day educational program can help successfully deal with these issues by educating women on how to address them. The study, published in the Journal of Sexual Medicine, underscores the need to inform women about the aftereffects of this type of surgery and, critically, let them know that such problems can be dealt with successfully.
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GENETICS


Decoding the emergence of metastatic cancer stem cells
Medical Xpress
Rice University researchers have mapped how information flows through the genetic circuits that cause cancer cells to become metastatic. The research, published in the Journal of the Royal Society Interface, reveals a common pattern in the decision-making that allows cancer cells to both migrate and form new tumors. Researchers say the commonality may open the door to new drugs that interfere with the genetic switches that cancer must flip to form both cancer stem cells and circulating tumor cells — two of the main players in cancer metastasis.
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The genetic test that could transform breast cancer care
The Huffington Post
Breast cancer prevention usually starts with breast self-exams in your 20s and progresses to yearly mammograms in your 40s. But if genome sequencing costs keep going down and knowledge about breast cancer risk genes keeps going up as it has, breast cancer prevention could start as early as birth, according to a new study in the journal Cancer Epidemiology, Biomarkers & Prevention.
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RESEARCH


Google developing a pill that would detect cancer and other diseases
Wired
Google is attempting to develop a pill that would send microscopic particles into the bloodstream in an effort to identify cancers, imminent heart attacks, and other diseases. Andrew Conrad, the head of life sciences inside the company’s Google X research lab, revealed the project at a conference here in Southern California. According to Conrad, the company is fashioning nanoparticles — particles about one billionth of a meter in width — that combine a magnetic material with antibodies or proteins that can attach to and detect other molecules inside the body.
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RISK


No increased cancer risk for infertile women
Medscape (Free login required)
A study published in the American Journal of Epidemiology showed that infertile women, whether or not they undergo treatment for in vitro fertilization (IVF), do not face an increased risk for cancer, according to three studies presented here at the American Society for Reproductive Medicine 2014 Annual Meeting. "Overall, the studies are reassuring," said Humberto Scoccia, MD, from the University of Illinois in Chicago, who was not involved in the research.
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Women's Cancer News
Colby Horton, Vice President of Publishing, 469.420.2601
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Jessica Taylor, Senior Medical Editor, 202-684-7169  
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