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Inside ADAA
Anxiety and Depression Association of America
Welcome to those who are new to Anxiety & Depression Insights. This resource is provided by the Anxiety and Depression Association of America for all who focus on anxiety disorders, OCD, PTSD and depression in children and adults. Education is key to ADAA. To that end, ADAA sponsored a recent episode of the Mimi Geerges Show on XM Sirius Public Radio. Mimi’s interview with Scott Stossel, author of the new book My Age of Anxiety: Fear, Hope, Dread, and the Search for Peace of Mind and editor of the The Atlantic, reached a potential audience of 25 million in the U.S. and Canada. Scott’s courageous story is key to ending stigma and helping those who need it find help. His story is a call to renew efforts to develop new treatments and offer training on the latest therapies to all who treat these disorders.

ADAA is the unified voice among clinicians, researchers and patients. We can help you educate patients, trainees and colleagues about these disorders. Visit ADAA’s website, ADAA.org, to access and share a wealth of resources.

Mark Pollack, M.D., ADAA President
Chair, Department of Psychiatry, Rush University Medical Center

Record Attendance Expected at Anxiety and Depression Conference 2014

ADAA is on target for record-breaking attendance at this year’s annual conference, next month in Chicago. ADAA is the single best source of training and education. The conference provides professionals at all levels an ideal place to network, discuss the latest research, generate referrals, and connect with others who have expertise in anxiety disorders, OCD, PTSD and depression. As part of the 150 plus sessions, there are 12 Master Clinician workshops on topics including eating disorders, substance abuse, suicide, social anxiety disorder, pharmacotherapy, CBT and DBT for children and adults. Earn up to 30 CME or CE credits. This continuing education meeting does one of the best jobs translating research and presenting treatment and practice information focusing on children and adults.

Cutting-Edge Management of Anxiety and Depression
March 29, Chicago Marriott Downtown, Chicago, Ill.

This one-day program is specially designed to meet the continuing medical education needs of psychiatrists, nurse practitioners, psychiatric nurses, and physicians focusing on the treatment of anxiety disorders and depression. This interactive session brings together nationally renowned experts focusing on refractory anxiety and depression including PTSD. There will be discussions of challenging cases and updates on pharmacotherapy and psychotherapy treatments for children and adults. The program offers 8 AMA PRA Category 1 Credits™. There will be opportunities to speak with experts, discuss your practice challenges and network with peers. Organized by the Anxiety and Depression Association of America in partnership with the Department of Psychiatry, Rush University Medical Center. Read more here.
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RESOURCES


New research in the treatment of social anxiety disorder
Depression and Anxiety Association
Listen to an interview with Dr. Stefan Hofmann about his research with a novel application of the drug d-cycloserine to treat social anxiety disorder.
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RESEARCH AND PRACTICE NEWS


Understanding heterogeneity in PTSD: Fear, dysphoria and distress
Depression and Anxiety
Fear, dysphoria, and distress are prominent components in the conceptualization of posttraumatic stress disorder (PTSD). However, because our diagnostic categories are open concepts, relying on observed patterns of symptoms for classification, it is unclear whether these components represent core or auxiliary features of the disorder — convergence across multiple indices is critical for this understanding. In this paper, we examine these components of PTSD across observed symptom patterns, broader theoretical conceptualizations, underlying information processing mechanisms of attention and memory, and underlying learning and neurobiological mechanisms.
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Naturalistic follow-up of youths treated for pediatric anxiety disorders
JAMA Network
Pediatric anxiety disorders are highly prevalent and impairing and are considered gateway disorders in that they predict adult psychiatric problems. Although they can be effectively treated in the short term, data are limited on the long-term outcomes in treated children and adolescents, particularly those treated with medication. The objective is to determine whether acute clinical improvement and treatment type predicted remission of anxiety and improvement in global functioning at a mean of 6 years after randomization and to examine predictors of outcomes at follow-up.
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Cancer doesn't increase post-traumatic stress disorder in children
Epoch Times
A study by St. Jude Children’s Research Hospital suggests previous research overestimated PTSD in young cancer patients. Their new findings highlight the ability of children to adjust and even thrive in response to challenges. The study found that despite being diagnosed with life-threatening illnesses, child cancer patients are no more likely than their healthy peers to develop post-traumatic stress disorder.
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Hypomania: Can antidepressants be reintroduced?
Medscape (free subscription)
Patients with major depression who experience an episode of antidepressant-associated hypomania (AAH) may be able to resume antidepressants without AAH recurrence, a 3-year follow-up study suggests. Results showed that patients in the study were able to resume antidepressant medications 2 weeks after AAH remitted with no recurrence of the condition, of episodes of mania, or of spontaneous hypomania after the course of the antidepressants was completed.
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Less than half of children treated for anxiety achieve long-term relief
Medical Xpress
Fewer than one in two children and young adults treated for anxiety achieve long-term relief from symptoms, according to the findings of a study by investigators from the Johns Hopkins Children's Center and five other institutions. Results of the federally funded research underscore the importance of vigilant follow-up and rigorous monitoring of symptoms among anxious children, teens and young adults — even when they seem to be on the mend — the investigators say.
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Study: Getting too much or too little sleep causes major depression in teens
University Herald
Getting the right amount of sleep might keep depression at bay, according to American Academy of Sleep Medicine study. Researchers said that sub-optimal sleep or too much sleep can trigger genes linked with the condition and increase the risk for major depression. For the study, the researchers conducted a genetic study of adult twins and a community-based study of adolescents — both the studies found a link between sleep duration and depression.
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Depression linked to adult-onset asthma
Medscape (free subscription)
Depressive symptoms may be linked to the development of adult-onset asthma, preliminary research suggests. A cohort of nearly 32,000 participants from the Black Women's Health Study showed that those with the highest depressive symptom scores were more than twice as likely to develop asthma as their counterparts with the lowest symptom scores.
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A long day's night: Winter can affect the body's natural sleep habits
By Denise A. Valenti
We are deep into winter and past the longest nights of the season. With long nights come short days, and seemingly endless nights for some. Despite the lack of sunlight, humans do not require additional hours of sleep to correspond to the additional hours in the night during the winter. But it is normal for the changes in weather and season to slightly influence activities and sleep habits. For some, the changes can be enough to cause disruptions in the circadian timing of body rhythms, which can contribute to depression and seasonal affective disorders.
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The developmental trajectory of bipolar disorder
The British Journal of Psychiatry
Bipolar disorder is highly heritable, and therefore longitudinal observation of children of affected parents is important to mapping the early natural history. This study aims to model the developmental trajectory of bipolar disorder based on the latest findings from an ongoing prospective study of the offspring of parents with well-characterized bipolar disorder.
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Women with MS, depression show alterations of brain structure
Psych Central
A new imaging study has shown that women with multiple sclerosis (MS) and some depressive symptoms were found to have reduced size of the right hippocampus — a brain structure that helps regulate mood. The findings, published in Human Brain Mapping, also revealed that the left hippocampus of these patients remained the same, and that other types of depression — including vegetative depression, which may result in extreme fatigue — were not linked to size reduction in the hippocampus.
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Researchers pinpoint neural circuitry that promotes stress-induced anxiety
News-Medical
According to the National Institute of Mental Health, over 18 percent of American adults suffer from anxiety disorders, characterized as excessive worry or tension that often leads to other physical symptoms. Previous studies of anxiety in the brain have focused on the amygdala, an area known to play a role in fear. But a team of researchers led by biologists at the California Institute of Technology had a hunch that understanding a different brain area, the lateral septum, could provide more clues into how the brain processes anxiety.
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New therapies offer bright hope against the darkness of depression
Los Angeles Times
The numbers are staggering: almost 7 percent of the U.S. adult population — about 17.6 million people — are diagnosed with depression, according to the National Institute of Mental Health. The national Centers for Disease Control and Prevention report that depression costs 200 million lost workdays each year at a cost to employers of $17 billion to $44 billion.
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Parent-delivered CBT reduces kids' anxiety
Medscape (free subscription)
Parent-delivered cognitive-behavioral therapy (CBT) guided by therapists is effective in treating child anxiety disorders, new research suggests. A randomized study of almost 200 children between the ages of 7 and 12 years in the U.K. showed that 50 percent of those in the full guided group recovered from their clinically diagnosed anxiety disorder after treatment versus 39 percent of those in the brief guided group.
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Depression severity marks suicide risk in bipolar patients
News-Medical
The likelihood for suicide ideation among patients with bipolar depression increases with the severity of the episode, shows a study in Indian patients. In particular, hopelessness, assessed on the Beck Hopelessness Scale, was a strong independent predictor for suicide ideation among the 130 patients in the study.
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Neuroscientists determine how treatment for anxiety disorders silences fear neurons
YottaFire
Excessive fear can develop after a traumatic experience, leading to anxiety disorders such as post-traumatic stress disorder and phobias. During exposure therapy, an effective and common treatment for anxiety disorders, the patient confronts a fear or memory of a traumatic event in a safe environment, which leads to a gradual loss of fear. A new study in mice, published online in Neuron, reports that exposure therapy remodels an inhibitory junction in the amygdala, a brain region important for fear in mice and humans.
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About Anxiety & Depression Insights
ADAA
This news brief is a timely update about anxiety disorders and depression sent to members of the Anxiety and Depression Association of America and other professionals interested in this area. Links to articles are provided for the convenience of the reader. External resources are not a part of the ADAA website, and ADAA is not responsible for the content of external sites. Linking to a website does not constitute an endorsement by ADAA of the sponsors of the site or the information presented on the site. For more information about ADAA, visit www.ADAA.org.
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