ASCLS eNewsBytes Archive

The genetic underground of antibiotic resistance

Metabolism has mostly been studied for its role in providing building blocks and energy to sustain cell duplication. Previously unexplored roles of metabolism in signaling and regulation have now been unveiled.

source: Science Magazine

Neanderthal genes may influence COVID-19 severity

Researchers worldwide have worked tirelessly to uncover how SARS-CoV-2 interacts with the body and why some people with COVID-19 remain virtually unaffected while others have severe, life threatening symptoms. The Centers for Disease Control and Prevention COVID-19 guidance...

source: Medical News Today

Scientists repair injured spinal cord using patients' own stem cells

Intravenous injection of bone marrow derived stem cells in patients with spinal cord injuries led to significant improvement in motor functions, researchers from Yale University and Japan report Feb. 18 in the Journal of Clinical Neurology and Neurosurgery.

source: Yale University via ScienceDaily

Healthy microbiome is key to sepsis management

The human gut microbiome is a major factor in sepsis development, yet a dearth of human studies means limited new therapies that utilize the microbiome as a method of treating bacterial sepsis effectively, according to a review published in The Journal of Infectious Diseases.

source: Infectious Disease Advisor

New study from UCSD shows that chromosome shattering can promote cancer cell growth and increase resistance to chemotherapeutic drugs

Anatomic pathologists who diagnose tissue and closely monitor advances in cancer diagnostics and therapy will be interested in a recent study into how a mutational process known as chromothripsis (chromosome...

source: Dark Daily

Lower daily temperatures lead to higher transmission of COVID-19

The SARS-CoV-2 pandemic has caused tremendous upheaval, leading to more than 2.4 million deaths worldwide and more than 500,000 in the United States. Understanding the impact of seasonal temperature changes on transmission of the virus...

source: Lab Manager

Scientists identify more than 140,000 virus species in the human gut

Viruses are the most numerous biological entities on the planet. Now researchers have identified over 140,000 viral species living in the human gut, more than half of which have never been seen before.

source: Wellcome Trust Sanger Institute via ScienceDaily

Inhaled antibody therapy to protect against new COVID variants

Aridis Pharmaceuticals Inc., a biopharmaceutical company focused on the discovery and development of novel anti-infective therapies to treat life-threatening infections, announced that it has augmented its inhaled AR-711 monoclonal antibody...

source: Outbreak News Today

Infection preventionists to play crucial role in vaccine efforts

Creating vaccines for COVID-19 and getting them approved by the U.S. Food and Drug Administration proved to be an arduous task fraught with scientific and logistical hurdles. Now comes the hard part: Getting those vaccines widely distributed...

source: Infection Control Today

HIV-positive people with severe immunosuppression, APOE4 gene may have increased risk for dementia

People living with HIV who have a history of severe immunosuppression and at least one copy of the Alzheimer's disease-related gene variant APOE4, might see a compounded adverse effect on the circuitry that impacts...

source: Georgetown University Medical Center via News-Medical.Net

Scientists developed a model for a peculiar type of breast cancer

Invasive lobular carcinoma is breast cancer that begins in one of the glands that make milk, called lobules. More than 90% of ILC tumors also contain estrogen receptors, meaning that they can receive hormone signals from the body, e.g.,...

source: Tech Explorist

How a longevity gene protects brain stem cells from stress

A gene linked to unusually long lifespans in humans protects brain stem cells from the harmful effects of stress, according to a new study by Weill Cornell Medicine investigators. Studies of humans who live longer than 100 years have shown that many share an unusual version...

source: Technology Networks

Younger non-Hispanic black patients with AML have worse overall survival rates than white patients

White patients with acute myeloid leukemia appear to benefit more from recent therapy developments compared with non-Hispanic Black patients in the United States, according to data published in Cancer Discovery. Specifically,...

source: Cancer Network

Identifying COVID-19 therapy candidates with machine learning

Investigators from the Massachusetts Institute of Technology, in collaboration with Harvard University and ETH Zurich, have developed a machine learning-based approach that can identify therapies that are already on the market that have...

source: ContagionLive

Ultra-rare but not forgotten: New drug development paradigms to treat the rarest of diseases

In addition to the most visible effects of COVID-19 — tragic deaths, lingering illness, economic turmoil, and more — the pandemic is affecting much that is out of the spotlight. One is research on the so-called...

source: STAT

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Universal vaccine for the flu may be just around the corner

The genetic underground of antibiotic resistance

Neanderthal genes may influence COVID-19 severity

Scientists repair injured spinal cord using patients' own stem cells

Healthy microbiome is key to sepsis management

New study from UCSD shows that chromosome shattering can promote cancer cell growth and increase resistance to chemotherapeutic drugs

Lower daily temperatures lead to higher transmission of COVID-19

Scientists identify more than 140,000 virus species in the human gut

Inhaled antibody therapy to protect against new COVID variants

Infection preventionists to play crucial role in vaccine efforts

HIV-positive people with severe immunosuppression, APOE4 gene may have increased risk for dementia

Scientists developed a model for a peculiar type of breast cancer

How a longevity gene protects brain stem cells from stress

Younger non-Hispanic black patients with AML have worse overall survival rates than white patients

Identifying COVID-19 therapy candidates with machine learning

Ultra-rare but not forgotten: New drug development paradigms to treat the rarest of diseases

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