ASPHO News Briefs Archive

Attend ASPHO's February Webinar: The Use of Yoga for Children with Cancer & Blood Disorders

Register for next month's ASPHO Webinar The Use of Yoga for Children with Cancer & Blood Disorders on Tuesday, February 28, at 3pm CT, to understand the benefits of yoga for PHO patients and to provide program development...

source: ASPHO

Build Subspecialty Knowledge and Community at the 2023 ASPHO Conference

Attend the 2023 ASPHO Conference, May 10-13, 2023, to strengthen your pediatric hematology/oncology practice and research with the latest clinical, basic, and translational science presented by more than 100 speakers at over 40 educational...

source: ASPHO

Genetic characteristics and treatment outcome in infants with KMT2A germline B-cell precursor acute lymphoblastic leukemia: Results of MLL-Baby protocol

The aim of this study was to present the diagnostic and outcome characteristics of infants with germline status of KMT2A gene (KMT2A-g) B-cell precursor acute lymphoblastic leukemia (BCP-ALL)...

source: Pediatric Blood & Cancer

The incidence and characterization of weight gain associated with MEK inhibitors in pediatric patients

Mitogen-activated protein kinase enzyme (MEK) inhibitors are used in the treatment of pediatric patients with neurofibromatosis, low grade glioma, and astrocytoma, and may demonstrate a unique side effect profile in...

source: Pediatric Blood & Cancer

Differentiated thyroid cancer in a pediatric population: Estimating the risk of recurrence and evolution over time

Differentiated thyroid cancer (DTC) is the most common endocrine cancer during childhood, and the prognosis is usually good. The 2015 American Thyroid Association (ATA) pediatric guidelines for DTC classify...

source: Cureus

Addition of interferon alfa to adjuvant temozolomide extends survival in high-grade glioma

The addition of interferon alfa to temozolomide significantly extended survival among patients with newly diagnosed high-grade gliomas, according to data published in JAMA Network Open. The temozolomide-interferon alfa combination...

source: HemOnc Today

Immersive virtual reality to distract from pain in children treated with L-asparaginase by intramuscular injection

Treatment-related pain and discomfort are two of the most common manifestations in children with acute lymphoblastic leukemia (ALL). Patients with ALL are usually treated with L-asparaginase (L-ASP) by intramuscular injection.

source: Cureus

FDA grants rare pediatric disease designation to OR-440 for treatment of adrenocortical carcinoma

Officials with the FDA have granted Rare Pediatric Disease Designation (RPDD) to OR-440, an investigational drug for the treatment of pediatric adrenocortical carcinoma (ACC). OR-449 is a selective, first-in-class, potent,...

source: Pharmacy Times

FDA approves Jaypirca for advanced mantle cell lymphoma

The FDA granted accelerated approval to pirtobrutinib for treatment of certain patients with advanced mantle cell lymphoma. The indication applies to use of the agent by adults with relapsed or refractory disease who received at least two lines of systemic therapy, including...

source: HemOnc Today

Mutational signatures profiled in pediatric cancers

A team led by researchers in Germany has systematically analyzed mutational signatures across more than two dozen pediatric cancer types or subtypes, providing a look at everything from processes behind the tumors to potential features or vulnerabilities linked to certain...

source: Genome Web

Moyamoya syndrome (MMS) in a patient with sickle cell disease (SCD) and protein S deficiency

The association between Moyamoya syndrome (MMS) and sickle cell disease (SCD) has been well-established in pediatric populations; however, limited literature exists documenting the characteristics and management of MMS in adult SCD patients.

source: Cureus

Survivorship and quality-of-life play important roles for patients with thyroid cancer

Survivorship does not just mean surviving cancer. According to Melanie Goldfarb, MD, MSc, FACS, FACE, it also means dealing with the physical, emotional, psychological aspects of one's diagnosis.

source: Targeted Oncology

NCCN recommends sodium thiosulfate to reduce the risk for cisplatin-induced hearing loss in pediatric patients

Fennec Pharmaceuticals announced an update to the National Comprehensive Cancer Network's (NCCN) practice guidelines for Adolescent and Young Adult (AYA) Oncology, calling for the use of sodium thiosulfate injection...

source: OncLive

International guidelines to help prevent and treat heart complications in pediatric oncology patients

The world's first international clinical guidelines to help prevent and treat heart complications in children undergoing cancer treatment have been created. The guidelines, published in JACC:Advances, cover cardiovascular...

source: News Medical Life Sciences

NUS scientists breathe new life into an existing drug to fight T-cell acute lymphoblastic leukemia

A team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore, led by Associate Professor Takaomi Sanda and Dr Lim Fang Qi, has breathed new life into an...

source: News Medical Life Sciences

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Study finds missing piece of pediatric cancer puzzle

Attend ASPHO's February Webinar: The Use of Yoga for Children with Cancer & Blood Disorders

Build Subspecialty Knowledge and Community at the 2023 ASPHO Conference

Genetic characteristics and treatment outcome in infants with KMT2A germline B-cell precursor acute lymphoblastic leukemia: Results of MLL-Baby protocol

The incidence and characterization of weight gain associated with MEK inhibitors in pediatric patients

Differentiated thyroid cancer in a pediatric population: Estimating the risk of recurrence and evolution over time

Addition of interferon alfa to adjuvant temozolomide extends survival in high-grade glioma

Immersive virtual reality to distract from pain in children treated with L-asparaginase by intramuscular injection

FDA grants rare pediatric disease designation to OR-440 for treatment of adrenocortical carcinoma

FDA approves Jaypirca for advanced mantle cell lymphoma

Mutational signatures profiled in pediatric cancers

Moyamoya syndrome (MMS) in a patient with sickle cell disease (SCD) and protein S deficiency

Survivorship and quality-of-life play important roles for patients with thyroid cancer

NCCN recommends sodium thiosulfate to reduce the risk for cisplatin-induced hearing loss in pediatric patients

International guidelines to help prevent and treat heart complications in pediatric oncology patients

NUS scientists breathe new life into an existing drug to fight T-cell acute lymphoblastic leukemia

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