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|The Obesity Society 2019 Call for Awards
The Obesity Society's (TOS) awards promote, reward, and encourage research in the field of obesity. Each award recognizes specific research achievements and major contributions to the basic science, treatment and prevention of obesity. Awards highlighting the careers and accomplishments of obesity researchers will be presented during TOS's 37th annual meeting held at ObesityWeek℠. ObesityWeek will be held November 3-7, 2019 in Las Vegas, NV.
TOS encourages its members to identify the talented and exceptional people in the field of obesity who deserve to be recognized and awarded for work in their field.
Nominations will be reviewed by The Obesity Society's Awards Committee and the recipients will be announced later this summer.
All award nominations should be submitted to firstname.lastname@example.org. Awards nominations must be received by Monday, July 1, 2019.
Atkinson-Stern Award for Distinguished Public Service
The George A. Bray Founders Award
The George A. Bray Master's Thesis Award
The George A. Bray Doctoral Dissertation Award
The TOPS Research Achievement Award
The Friends of Albert (Mickey) Stunkard Lifetime Achievement Award
Thomas A. Wadden Award for Distinguished Mentorship
Contact Regina Williams at email@example.com for more information.
|Workshop to Focus on MRI of Obesity and Metabolic Disorders
Senior investigators and junior scientists are encouraged to register for the International Society for Magnetic Resonance in Medicine (ISMRM) Workshop on MRI of Obesity & Metabolic Disorders. This workshop will be held July 21–24, 2019, at the Matrix Building in Singapore.
Magnetic resonance imaging and spectroscopy have become widely used to quantify not only fat accumulation in adipose tissue depots, organs, and muscles, but also the molecular substrates, products, and dynamic rates of metabolism and biochemical pathways. As a follow-up to the 2012 ISMRM workshop held in Long Beach, California, on water-fat MRI, the purpose of this proposed workshop is to bring together and reunite internationally recognized scientists and clinicians who are currently developing and applying advanced MRI and MRS techniques to investigate the causes and consequences of obesity and metabolic dysfunctions.
Continuing Medical Education credits will not be offered for the workshop.
Early-bird registration rates end on July 8, 2019.
Register now and book your hotel reservation.
Read more about the workshop.
|Advanced Therapies for Pediatric Obesity Oct. 4, 2019
University of Minnesota Masonic Children’s Hospital
PRESENTED BY: Center for Pediatric Obesity Medicine (CPOM)
Claudia Fox, MD, MPH, Associate Professor, CPOM Co-Director
Aaron S. Kelly, PhD, Associate Professor, CPOM Co-Director, Department of Pediatrics, University of Minnesota
Advanced Therapies for Pediatric Obesity (ATPO) is a workshop with a focus on youth with severe obesity who are often unable to lose a clinically-meaningful amount of weight with lifestyle modification alone. Pharmacological therapies are emerging as a recognized adjunctive strategy to address this otherwise recalcitrant disease, yet no guidelines currently exist for the responsible clinical use of obesity pharmacotherapy in the pediatric patient.
This workshop is offered as a Continuing Education designated activity with up to 6.75 AMA PRA Category1 Credits™. ATPO invites healthcare providers, researchers, and others interested in the clinical management of pediatric obesity while utilizing case studies, lectures and group discussions.
Following completion of this activity, attendees will be better able to utilize pharmacotherapy for pediatric obesity in a safe and responsible fashion, identify biological targets of obesity treatments, and identify the mechanisms of action and outcomes of current FDA-approved and off-label medications for the treatment of obesity in adults and youth. Workshop enrollment is limited.
For more information or to register, visit http://www.z.umn.edu/PedsObesity
|TOS Members' Articles Selected as Obesity Editors' Choice
Metabolic Determinants of Weight Gain in Humans
TOS Member Author: Paolo Piaggi
One of the fundamental challenges in obesity research is to identify subjects prone to gain weight so that obesity and its comorbidities can be promptly prevented or treated. The principles of thermodynamics as applied to human body energetics demonstrate that susceptibility to weight gain varies among individuals as a result of inter-individual differences in energy expenditure and energy intake, two factors that counterbalance one another and that together determine daily energy balance and, ultimately, bodyweight change. This review focuses on the variability among individuals in human metabolism that determines weight change. Conflicting results have been reported about the role of inter-individual differences in energy metabolism during energy balance in relation to future weight change. However, recent studies show that metabolic responses to acute, short-term dietary interventions that create energy imbalance, such as low-protein overfeeding or fasting for 24 hours, may reveal the underlying metabolic phenotype that determines the degree of resistance to diet-induced weight loss or the propensity to spontaneous weight gain over time. Metabolically “thrifty” individuals, characterized by a predilection for saving energy in settings of undernutrition and dietary protein restriction, display a minimal increase in plasma Fibroblast Growth Factor 21 (FGF21) concentrations in response to a low-protein overfeeding and tend to gain more weight over time compared with metabolically "spendthrift" individuals. Similarly, interindividual variability in the causal relationship between energy expenditure and energy intake ("energy sensing") and in the metabolic response to cold exposure (e.g., brown adipose tissue activation) seems, to some extent, to be indicative of individual propensity to weight gain. Thus, an increased understanding and the clinical characterization of phenotypic differences in energy metabolism among individuals (metabolic profile) may lead to new strategies to prevent weight gain or improve weight-loss interventions by targeted therapies on the basis of metabolic phenotype and susceptibility to obesity in individual persons.
Mediterranean Versus Western Diet Effects on Caloric Intake, Obesity, Metabolism, and Hepatosteatosis in Nonhuman Primates
TOS Member Author: Mara Z. Vitolins
Objective: This study aimed to determine the effects of humanlike Western and Mediterranean diets on caloric intake, obesity, metabolism, and hepatosteatosis in an established nonhuman primate model of obesity, cardiometabolic syndrome, type 2 diabetes, and atherosclerosis.
Methods: A 38‐month, randomized, preclinical, nonhuman primate primary prevention trial of 38 socially housed, middle‐aged adult females was conducted. The monkeys were characterized during a 7‐month baseline phase while consuming chow and then randomized to either Western or Mediterranean diets; the groups were balanced on baseline characteristics. Western and Mediterranean diets were formulated to closely reflect human diets, matched on macronutrient content, with protein and fat derived largely from animal sources in the Western diet and plant sources in the Mediterranean diet. Food consumption, activity levels, energy expenditure, body composition, carbohydrate metabolism, and hepatosteatosis were measured during baseline and treatment phases.
Results: The Western diet increased caloric intake for the first 6 months and body fat, activity, energy expenditure, insulin resistance, and hepatosteatosis after 2.5 years, whereas the Mediterranean diet reduced triglyceride levels.
Conclusions: This is the first report of differential caloric intake and obesity with long‐term consumption of a Western versus Mediterranean diet under controlled experimental conditions and the first experimental evidence that a Mediterranean diet protects against hepatosteatosis compared with a Western diet.
Assessing the Role of 98 Established Loci for BMI in American Indians
TOS Member Authors: Paolo Piaggi, Clifton Bogardus
Objective: Meta‐analyses of genome‐wide association studies in Europeans have identified > 98 loci for body mass index (BMI). Transferability of these established associations in Pima Indians was analyzed.
Methods: Among 98 lead single nucleotide polymorphisms (SNPs), 82 had minor allele frequency ≥ 0.01 in Pima Indians and were analyzed for association with the maximum BMI in adulthood (n = 3,491) and BMI z score in childhood (n = 1,958). Common tag SNPs across 98 loci were also analyzed for additional signals.
Results: Among the lead SNPs, 13 (TMEM18, TCF7L2, MRPS33P4, PRKD1, ZFP64, FTO, TAL1, CALCR, GNPDA2, CREB1, LMX1B, ADCY9, NLRC3) were associated with BMI (P ≤ 0.05) in Pima adults. A multi‐allelic genetic risk score (GRS), which summed the risk alleles for 82 lead SNPs, showed a significant trend for a positive relationship between GRS and BMI in adulthood (beta = 0.48% per risk allele; P = 1.6 × 10−9) and BMI z score in childhood (beta = 0.024 SD; P = 1.7 × 10−7). GRS was significantly associated with BMI across all age groups ≥ 5 years, except for those ≥ 50 years. The strongest association was seen in adolescence (age 14‐16 years; P = 1.84 × 10−9).
Conclusions: In aggregate, European‐derived lead SNPs had a notable effect on BMI in Pima Indians. Polygenic obesity in this population manifests strongly in childhood and adolescence and persists throughout much of adult life.
|New Virtual Issue: Recent Best of Obesity
Editors of Obesity
Researchers who publish their findings in the official TOS journal make important contributions to the global fight against obesity. The editors of Obesity are proud to share some of the journal's recent top papers in a free virtual issue. Help extend the impact of their commitment and hard work by citing these articles and sharing them with your colleagues.
Here is a small sample of the articles; read the full list (and find out if one of your articles is included) by visiting the journal website.
Association Between Weight Bias Internalization and Metabolic Syndrome Among Treatment‐Seeking Individuals with Obesity
Rebecca L. Pearl, Thomas A. Wadden, Christina M. Hopkins, Jena A. Shaw, Matthew R. Hayes, Zayna M. Bakizada, Nasreen Alfaris, Ariana M. Chao, Emilie Pinkasavage, Robert I. Berkowitz, and Naji Alamuddin.
The Accumulating Data to Optimally Predict Obesity Treatment (ADOPT) Core Measures Project: Rationale and Approach
Paul S. MacLean, Alexander J. Rothman, Holly L. Nicastro, Susan M. Czajkowski, Tanya Agurs‐Collins, Elise L. Rice, Anita P. Courcoulas, Donna H. Ryan, Daniel H. Bessesen, and Catherine M. Loria.
Serum Chemerin is Associated with Inflammatory and Metabolic Parameters—Results of a Population‐Based Study
Stephanie Zylla, Maik Pietzner, Jens‐Peter Kühn, Henry Völzke, Marcus Dörr, Matthias Nauck, and Nele Friedrich.
BMI z‐Scores are a Poor Indicator of Adiposity Among 2‐ to 19‐Year‐Olds with Very High BMIs, NHANES 1999‐2000 to 2013‐2014
David S. Freedman, Nancy F. Butte, Elsie M. Taveras, Elizabeth A. Lundeen, Heidi M. Blanck, Alyson B. Goodman, and Cynthia L. Ogden.
Circulating Adipocyte‐Derived Exosomal MicroRNAs Associated with Decreased Insulin Resistance After Gastric Bypass
Monica J. Hubal, Evan P. Nadler, Sarah C. Ferrante, Matthew D. Barberio, Jung‐Hyuk Suh, Justin Wang, G. Lynis Dohm, Walter J. Pories, Michelle Mietus‐Snyder, and Robert J. Freishtat.
|ObesityWeek℠ 2019 Late-Breaking Abstracts Opens in July
The Obesity Society Late-Breaking Abstracts
OPENS FRIDAY, JULY 12, 2019
The Call for Late-Breaking Abstracts will open July 12, 2019 and will close July 29, 2019. Don't miss this chance to present Nov. 4–Nov. 8, in Las Vegas, NV, among your peers and colleagues. Notification of acceptance will be emailed in late September from firstname.lastname@example.org. Accepted abstracts will be presented Nov. 5-7 at ObesityWeek 2019. Please make travel plans to accommodate possible presentation times.
Submit your abstract to one of the following tracks:
Track 1: Metabolism and Integrative Physiology
Track 2: Neuroscience
Track 3: Intervention and Clinical Studies
Track 4: Population Health
Track 6: Health Care Policy/Public Health Policy
|TOS Review Course for the ABOM Exam
Are you taking the ABOM Exam? Take The Obesity Society (TOS) Review Course Nov. 3–4, 2019, in Las Vegas, NV, and stay for the Exam Prep track at ObesityWeekSM.
This highly interactive session includes instruction from leading obesity educators, board-exam style questions and answers, and a workbook of slides to take home for future study. TOS Review Course follows the ABOM rubric, giving you the most concise and yet sufficiently detailed material to enhance your knowledge of exam questions. Earn all 30 required Group One Credits by attending both the Review Course and ObesityWeek.
View the Review Course schedule
After taking the course, check out the conference schedule and stay for scientific sessions. Continue your preparation by following the Obesity Medicine Exam Prep Track!
|Join or Renew your Membership Today!
TOS is the leading professional society for obesity clinicians, researchers and academics working to treat and prevent the disease of obesity. The Society’s focus is to advance the science-based understanding of the causes, consequences, prevention and treatment of obesity. A variety of professionals—from basic scientists, to weight-loss physicians to industry researchers—benefit greatly from the career advancement opportunities provided by TOS.
Join or renew your membership as part of your maximum savings during ObesityWeek registration! Learn more about TOS Membership Benefits.
|TOS Job Center—Job Listings Exclusively for the Obesity Community
Attention employers, recruiters and job seekers! The Obesity Society (TOS) offers an opportunity to connect with others in the obesity community through our online Job Center. Jobseekers can post a resume, search for available job opportunities and create a personalized job alert. Recruiters can search for qualified candidates as well as post jobs—all at the click of a button.
CHECK OUT THE JOB CENTER.
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