ASCLS eNewsBytes
Mar. 31, 2015

White House releases action plan on antibiotic resistance
Medscape
The Obama administration has issued a detailed plan to address the problem of antibiotic resistance, complete with milestones to help ensure the goals are actively addressed. Drug-resistant bacteria cause 23,000 deaths and 2 million illnesses a year in the United States, according to the Centers for Disease Control and Prevention. Resistance also threatens animal health and agriculture, said the White House.More

Medical Laboratory Professionals Week — April 19-25
ASCLS
It is time to celebrate and educate others about what you do! Start planning your celebration now. Purchase official logo items, download the logo and more at www.ascls.org/MLPW. #Lab4LifeMore

April 16 webinar: A Rational Approach to Emerging Pathogen Biosafety Considerations
ASCLS
Dr. Michael Pentella of the Massachusetts Department of Public Health will discuss the biosafety considerations regarding test performance from specimens that may contain emerging pathogens and present a serious concern to staff and management. For more information and to register, go to www.ascls.org/webinars. ASCLS members receive a discounted registration rate. More

Scientists coax stem cells to form 3-D mini lungs
University of Michigan via Lab Manager
Scientists have coaxed stem cells to grow the first 3-D mini lungs. Previous research has focused on deriving lung tissue from flat cell systems or growing cells onto scaffolds made from donated organs. More

Several studies identify problems in reporting of clinical trial data; HHS and NIH propose tougher requirements for reporting clinical trial results
DARK Daily
Increased transparency is coming to clinical trials because of proposed new federal rules. Although the greatest impact will be on drug trials and pharmaceutical research, experts believe that developers of new diagnostic technologies and clinical laboratory tests will benefit as a result of easier access to the public data filed by researchers. More

Genetic test for inherited kidney diseases developed
Washington University School of Medicine in St. Louis via Medical Xpress
Many kidney disorders are difficult to diagnose. To address this problem, scientists and clinicians have developed a diagnostic test that identifies genetic changes linked to inherited kidney disorders. This testing is now available nationwide through Genomic Pathology Services at Washington University School of Medicine in St. Louis.More

C. difficile doubles hospital readmission rates, lengths of stay
Elsevier via ScienceDaily
Patients with Clostridium difficile infection are twice as likely to be readmitted to the hospital as patients without the deadly diarrheal infection, according to a new study. Researchers from the Detroit Medical Center, a seven-hospital system in southeastern Michigan, conducted a large study to understand the epidemiology of C-diff infection readmissions, analyzing 51,353 all-cause discharges between Jan. 1 and Dec. 31, 2012.More

Wounds heal faster with help from nanoparticles
Medical News Today
Researchers who are working on a way to use nanoparticles to hasten wound healing see their therapy being useful for all sorts of wounds from surgical incisions to diabetic ulcers. The team, from the Albert Einstein College of Medicine of Yeshiva University, Bronx, New York, has tested the experimental nanoparticle therapy on mice and showed it cut the time it takes for skin wounds to heal by half compared with no treatment. More

HIV can spread early, evolve in patients' brains
National Institutes of Health via Infection Control Today
The AIDS virus can genetically evolve and independently replicate in patients' brains early in the illness process, researchers funded by the National Institutes of Health have discovered. An analysis of cerebral spinal fluid, a window into brain chemical activity, revealed that for a subset of patients HIV had started replicating within the brain within the first four months of infection. More

Study: More dangerous Ebola strain unlikely
HealthDay News
Ebola likely won't mutate into a strain that goes airborne or dodges current efforts to develop effective vaccines, tests and treatments for the deadly virus, a new study suggests. That's because the Ebola virus has been mutating at its normal pace during the current West African epidemic, researchers report in the March 26 issue of the journal Science.More

Stem-cell therapy promising for Type 2 diabetes
MedPage Today
Human embryonic stem-cell therapy was recently shown to reverse Type 1 diabetes in mice, and now new mouse studies suggest a role for stem cells in the treatment of Type 2 diabetes. Obese, diabetic mice treated with a combination of transplanted stem-cell-derived pancreatic progenitor cells and insulin-sensitizing drugs showed improved glucose metabolism and rapid weight loss. More