ASCLS eNewsBytes
Aug. 11, 2015

Clot-busting nanocapsule could 'revolutionize stroke and heart attack treatment'
Medical News Today
A new study suggests that using nanocapsules to precisely target activated clotting platelets with clot-busting drugs could revolutionize the treatment of stroke and heart attack. A report on the research, led by the University of Melbourne and the Baker IDI Heart and Diabetes Institute in Australia, is published in the journal Advanced Materials.More

CDC: 37,000 US infection-related deaths preventable over 5 years
Reuters
Closer coordination between healthcare facilities and public health departments could save 37,000 U.S. lives over five years by preventing infections from antibiotic-resistant germs and from a nasty intestinal bug called Clostridium difficile, according to a government report. Germs that no longer respond to antibiotics cause more than 2 million illnesses and 23,000 deaths each year in the United States, according to the report from the U.S. Centers for Disease Control and Prevention.More

Reliable, high-quality clinical laboratories continue to be in short supply in Nigeria despite efforts to upgrade accreditation and professionalism
DARK Daily
In Nigeria, government officials and medical laboratory scientists are speaking out about the poor state of medical diagnoses across the country despite their efforts to upgrade accreditation and professionalism of the clinical laboratories that operate in Nigeria. The widespread call for all medical laboratories to operate according to international standards reflects recognition by patients that they are not getting quality care in the African nation's clinical laboratories. More

Important regulation of cell invaginations discovered
Lund University via ScienceDaily
Lack of microinvaginations in the cell membrane, caveolae, can cause serious diseases such as lipodystrophy and muscular dystrophy. Researchers have now discovered a "main switch" that regulates the formation of these invaginations. More

More exemptions, more outbreaks
Lab Manager
Lax state vaccination laws contribute to lower immunization rates and increased outbreaks of preventable diseases — like whooping cough and measles — according to a new study from the University of Georgia. Through their research, released in the August issue of the journal Health Affairs, study authors David Bradford and Anne Mandich found higher rates of pertussis, or whooping cough, in states that allowed philosophical exemptions and used a standardized exemption form.More

Single-dose Ebola vaccine is safe and effective in monkeys against outbreak strain
NIH/National Institute of Allergy and Infectious Diseases via Infection Control Today
National Institutes of Health scientists report that a single dose of an experimental Ebola virus vaccine completely protects cynomolgus macaques against the current outbreak strain when given at least seven days before exposure, and partially protects them if given three days prior. The live-attenuated vaccine uses genetically engineered vesicular stomatitis virus to carry an Ebola virus gene that has safely induced protective immunity in macaques. More

Study: HIV cells keep duplicating even when treatments are working
HealthDay News
HIV can continue to multiply in patients who are responding well to antiretroviral therapy, U.K. researchers say. Treatment advances over the last 30 years mean that HIV — the virus that causes AIDS — is suppressed to almost undetectable levels in many patients, and they can live a long and healthy life. More

Laboratory-grown muscle fibers may help people with muscular dystrophy
Medical Daily
Producing large quantities of muscle fibers has proven to be difficult inside a laboratory. Until now, researchers have been able to create contracting muscles as well as muscle that is 10 times stronger than our own, albeit in small quantities. Researchers at Brigham and Women's Hospital have just changed all that.More

ICD-10 conversion could put financial squeeze on clinical laboratories and pathology groups
DARK Daily
Physicians are not the only ones with a large stake in the conversion from ICD-9 to ICD-10 that takes place Oct. 1. Clinical laboratories and anatomic pathology groups will be watching to see whether physicians include appropriate ICD-10 codes on laboratory test forms for Medicare patients.More