ASCLS eNewsBytes
Nov. 18, 2014

Molecular time signaling controls stem cells during brain's development
Researchers at Karolinska Institutet in Sweden have succeeded in explaining how stem cells in the brain change to allow one type of stem cell to produce different cell types at different stages. In a study being published in the journal Neuron, researchers show that the signal molecule TGF-beta acts as a time signal that regulates the nerve stem cells' potential at different stages of the brain's development — knowledge that may be significant for future pharmaceutical development.More

Genetic testing for personalized nutrition leads to better outcomes
University of Toronto via Science Codex
Researchers from the University of Toronto report that personalized dietary advice based on a person's genetic makeup improves eating habits compared to current "one-size-fits-all" dietary recommendations. The findings were published online in the journal PLoS One.More

Researchers find a way to deliver HIV drugs to infants through baby formula
Medical News Today
Researchers from the College of Agricultural Sciences at Pennsylvania State University say they have found a way to deliver an anti-retroviral drug to infants and young children through a baby formula — a method that could significantly improve treatment for the 3.2 million children worldwide living with HIV.More

'Blind spots' in DNA may conceal cancer genes
Medical News Today
Although gene-reading technology is advanced and sophisticated, there are certain parts of DNA that it does not cope with perfectly; for instance, there are repetitive areas of DNA that cause the machinery to "stutter." But there is a way to examine these "blind spots" and discover if they conceal cancer genes.More

No safety concerns yet in trials of GSK's Ebola vaccine
Almost 200 people have received GlaxoSmithKline's experimental Ebola vaccine in trials in the United States, Britain, Mali and Switzerland, and the safety data so far are "very satisfactory," scientists said. The trials have been using healthy volunteers, rather than patients with Ebola, to test whether the vaccine is safe for humans.More

Nanotechnology-based medical laboratory test chip developed at Stanford University detects Type 1 diabetes in minutes and can be used in doctors' offices
DARK Daily
New nanotechnology has made it possible for a team at Stanford University School of Medicine to develop a medical laboratory test for Type 1 diabetes that can be performed in a physician's office and does not require a specimen collected by venipuncture. This microchip requires just minutes to diagnose Type 1 diabetes in near-patient settings, according to a Stanford University news release. More

Study: Heart device may cut stroke risk in those with irregular heartbeat
HealthDay News
A new implanted heart device might be more effective than blood-thinning medications in reducing stroke risk for people suffering from the heart rhythm disorder known as atrial fibrillation, researchers report. The device called WATCHMAN proved better than the commonly used anti-clotting drug warfarin in preventing strokes, blood clots and deaths among atrial fibrillation patients, the study found.More

Study: Likely Ebola cases entering UK and US through airport screening
University of Liverpool via Infection Control Today
Researchers at the University of Liverpool's Institute of Infection and Global Health have found that screening for Ebola at airports could be an effective method for preventing the spread of the disease into the U.K. and U.S., but due to the long incubation period of the virus, screening won't detect all cases. Published in The Lancet, the study used a mathematical model to test the probability of infected travelers from West Africa entering the U.K. and U.S.More

Direct generation of neural stem cells could enable transplantation therapy
Lab Manager
Induced neural stem cells created from adult cells hold promise for therapeutic transplantation, but their potential in this capacity has been limited by failed efforts to maintain such cells in the desirable multipotent neural stem cell state without continuous expression of the transcription factors used initially to reprogram them. More

Drugs that prevent blood clots may protect organs during transplantation
Wiley via ScienceDaily
Organs can become significantly damaged during transplantation, but a new article offers a protective strategy that could keep them safe and allow them to function optimally after the procedure.More