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Home    About    Scholarships    Meetings    Publications    Resources Jan. 18, 2011
ASCLS eNewsBytes
Jan. 18, 2011
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Biomedical breakthrough: Blood vessels for lab-grown tissues
ScienceDaily    Share   Share on FacebookTwitterShare on LinkedinE-mail article
Researchers from Rice University and Baylor College of Medicine have broken one of the major roadblocks on the path to growing transplantable tissue in the lab: They've found a way to grow the blood vessels and capillaries needed to keep tissues alive. "The inability to grow blood-vessel networks — or vasculature — in lab-grown tissues is the leading problem in regenerative medicine today," said lead co-author Jennifer West, department chair and the Isabel C. Cameron Professor of Bioengineering at Rice. "If you don't have blood supply, you cannot make a tissue structure that is thicker than a couple hundred microns." More

NDM-1 superbugs a growing concern
Reuters via Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Enterobacteria carrying the NDM-1 (New Delhi metallo-beta-lactamase 1) resistance genes were isolated in India as early as 2006, a new study shows. The NDM-1 resistant strains accounted for 15 of the 26 carbapenemase producing Enterobacteriaceae isolated in 2006-2007 from various hospitals in India, researchers say in a report in Antimicrobial Agents and Chemotherapy. More

Scientists find inflammation immune cell switch
Reuters    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists have found a protein that acts as a "master switch" to determine whether certain white blood cells will boost or dampen inflammation, a finding that may help the search for new drugs for rheumatoid arthritis. Many patients with rheumatoid arthritis are treated with a class of drugs known as tumor necrosis factor (TNF) inhibitors made by various drug firms including Abbott Laboratories, Merck & Co, Pfizer and Amgen. But around 30 percent of patients don't respond to anti-TNF drugs, so experts say there is an urgent need to develop more widely effective treatment options. More

American Thoracic Society issues guidelines on treating pulmonary fungal infections
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The American Thoracic Society (ATS) has issued updated clinical guidelines on treating pulmonary fungal infections, according to a statement in the American Journal of Respiratory and Critical Care Medicine. The new recommendations, which replace 1988 ATS guidelines and target pulmonary, and critical care practitioners and trainees, describe new medications and treatment approaches to pulmonary fungal infections, as well as provide an overview of emerging fungi. More

Van Andel Research Institute develops method that triples genetic information from newborn blood spots
The Grand Rapids Press via    Share    Share on FacebookTwitterShare on LinkedinE-mail
A new testing method developed by Van Andel Research Institute researchers triples the amount of genetic information that can be obtained from dried spots of newborn blood preserved by the state Department of Community Health. The archived newborn blood, which comes from a poke in the heel a day or two after birth, can be used to study public health issues, research the causes of disease and ultimately could lead to prevention and early detection of illness, officials said. More

Stem cells could provide unlimited platelet supply
Los Angeles Times    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Chemotherapy, radiation treatments, organ transplants and illness can all depress numbers of platelets — the cell fragments in the blood that help form clots — in the human body. Patients often need platelet transfusions. … Researchers wrote in the journal Cell Research, pluripotent stem cells — that is, cells that have the potential to turn into any other type of cell in the body — might one day provide a way to generate "an unlimited supply of platelets for transfusion" in the laboratory. More

Proton-pump inhibitor with clopidogrel safe after stroke
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new study suggests that proton-pump inhibitors (PPIs) as a class are not associated with an increased short-term risk for recurrent stroke or death among older adults treated with clopidogrel after stroke. From this nested case-control study, "there's no large signal of harm with PPIs in patients taking clopidogrel for secondary stroke prevention," first author David N. Juurlink, M.D., Ph.D., from the Sunnybrook Health Sciences Center, Toronto, Ontario, Canada, told Medscape Medical News. More

Chickens genetically modified to keep from spreading bird flu
Reuters via MSNBC    Share    Share on FacebookTwitterShare on LinkedinE-mail article
British scientists have developed genetically modified chickens that cannot transmit bird flu infections — a step that in future could reduce the risk of avian flu spreading and causing deadly epidemics in humans. Scientists from Cambridge and Edinburgh universities said that while the transgenic chickens still got sick and died when they were exposed to H5N1 bird flu, they didn't transmit the virus to other chickens they came into contact with. More

Gene test finds disease risk in parents
Reuters    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new test for genetic mutations in parents might help prevent conception of babies with deadly inherited diseases, U.S. researchers reported. The test — the brainchild of a biotech CEO whose young daughter has a deadly and incurable genetic disease — can detect more than 500 recessive genetic diseases before a child is even a twinkle in the parents' eyes. More
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