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March 30, 2010
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Palpable breast cancers more common in women not having annual mammography
Medscape Medical News    Share   Share on FacebookTwitterShare on LinkedinE-mail article
Palpable breast cancers are more common in women not having annual mammography, according to the results of a study reported in the Journal of the American College of Surgeons. Despite the frequent use of screening mammography, 43 percent of breast cancers presented symptomatically or as a palpable mass. "This study confirms the importance of participation in screening mammography, since a palpable presentation was least common in women undergoing mammographic screening at the recommended interval of one year," senior author Amy C. Degnim, MD, associate professor of surgery at the Mayo Clinic in Rochester, Minn. More
Beckman Coulter

Sex virus blamed for rise in head and neck cancers
Reuters    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The number of head and neck cancers linked to a virus spread by oral sex is rising rapidly and suggests boys as well as girls should be offered protection through vaccination, doctors said. More

Responding to large-scale testing errors
American Journal of Clinical Pathology via Medscape    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Extensive use of automation in the clinical laboratory creates the potential for systematic errors that affect a large number of patient results before the error is discovered. When a large-scale testing error is found, the approaches recommended for responding to individual medical mishaps are often inadequate. This report uses two case studies to illustrate some of the unique challenges facing laboratory managers confronted with a large-scale testing error. We identify nine distinct constituencies that may be impacted by large-scale testing errors, each of which requires laboratory management's thoughtful and timely attention. More

Immune cells use 'bungee of death' to kill dangerous cells, new research shows
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Immune cells ensnare dangerous cells that are on the run with a bungee-like nanotube, according to research in the Proceedings of the National Academy of Sciences. The study, by researchers from Imperial College London, shows that natural killer cells use this bungee to destroy cells that could otherwise escape them. More

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H1N1 virus more like 1918 flu than modern cousins; explains infection patterns
The Canadian Press via Google News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The pandemic H1N1 virus more closely resembles the 1918 Spanish flu virus than more modern cousins in the same flu family, new research shows - a finding which helps explain the age pattern of H1N1 infections. Like the Spanish flu virus, the pandemic H1N1 lacks two sugar coats seen on contemporary viruses from the same family, the work reveals. More
Related story:  Resistance can develop fast with swine flu (Reuters)

Common gene abnormalities found in many types of cancers
DARK Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Pathologists and other clinical laboratory scientists can expect to see a number of multi-biomarker genetic tests for cancer as a result of research that is identifying specific gene abnormalities that are common to certain cancers and promote the growth of these cancers. Variations in these mutations make a difference in the effectiveness of certain treatments. With the aid of recent advances in genomic mapping technology, an international team led by researchers at the Dana-Farber Cancer Institute and the Broad Institute have found that many of these aberrations in the genetic code are shared by a variety of cancers occurring in many different types of tissues. More

Existing antibiotic might help keep wraps on AIDS virus
Science News via U.S. News & World Report    Share    Share on FacebookTwitterShare on LinkedinE-mail article
An inexpensive antibiotic might complement standard drugs in fighting the AIDS virus, a new study shows. The drug, called minocycline, has been used for decades to control acne, but the new findings suggest it inhibits HIV that has infected cells from reactivating and replicating itself. The report will appear in the Journal of Infectious Disease. More

Tuberculosis: Drug-resistant strains still spreading at deadly rates, W.H.O. report says
The New York Times    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Drug-resistant tuberculosis killed about 150,000 people in 2008, and half of all the world's cases are thought in be in China and India, the World Health Organization said in a report. No one knows the exact number of cases of the two types of drug-resistant TB, called MDR and XDR for multidrug-resistant and extensively drug-resistant. More

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