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ASCLS eNewsBytes
April 21, 2009
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Updated Guidelines for HIV-Associated Opportunistic Infections Released
from Infection Control Today
The first complete update in five years of the U.S. guidelines for preventing and treating HIV-associated opportunistic infections has been released by the National Institutes of Health and the Centers for Disease Control and Prevention in cooperation with the HIV Medicine Association of the Infectious Diseases Society of America. The new Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents apply state-of-the-art science and medicine to 29 infectious diseases of concern. More    E-mail article

Beckman Coulter

NIH Eases Restrictions on Stem Cells
from Time magazine
The National Institutes of Health made good on its charge from President Obama in March to come up with a less restrictive plan for federal funding of human embryonic stem cell research. The agency's proposed policy would allow unused embryos from infertility clinics to be included in stem cell research supported by taxpayer dollars. It is a significant advance for the field. More    E-mail article

Standardization of Platelet Function Testing by Aggregometry Through New CLSI Guideline
from The American Society for Clinical Pathology
It has been known for a long time that platelets play a vital role in hemorrhagic, thrombotic, and ischemic disorders. While clinical laboratories over the years have performed many different tests of platelet function, there has been very little, if any, standardization of procedures globally. More    E-mail article

Possible Way to Block the Spread of Deadly Brain Tumors Discovered
from Science Daily
Researchers at the Translational Genomics Research Institute may have found a way to stop the often-rapid spread of deadly brain tumors. A gene with the playful-sounding name NHERF-1 may be a serious target for drugs that could prevent malignant tumors from rapidly multiplying and invading other parts of the brain, according to a cover story in Neoplasia, an international journal of cancer research. More    E-mail article

Biomarkers for Alzheimer's Disease
from Medscape Medical News
Because Alzheimer's disease is primarily a diagnosis of exclusion, an objective diagnostic test is sorely needed. Although patients with AD are known to have altered levels of cerebrospinal fluid tau protein and beta-amyloid 42 (A beta 42) peptide, the association between these biomarkers and brain neuropathology is still unknown. Subscription required.    E-mail article

Urine Test Could Gauge Smokers' Lung Cancer Risk
from U.S. News & World Report
Someday, a simple urine test might spot smokers at highest risk for lung cancer, scientists report. The research is still in its preliminary stages, and it may be years before such a test becomes publicly available. But if it works, the urine-based screen could give added motivation to smokers who can't find other reasons to quit, said study author Dr. Jian-Min Yuan, an associate professor at the University of Minnesota. More    E-mail article


Melorheostosis in the Upper Extremity
from Ortho SuperSite
Melorheostosis is a rare mesodermal disease affecting the skeleton and adjacent soft tissues. Often it is incidentally detected on radiographs. In the standard radiology and orthopedics literature, melorheostosis is described as a "flowing hyperostosis, resembling dripping candle wax as an incidental radiographic finding." More    E-mail article

Ambitious Plan to Sequence Large Number of Cancer Genomes
from Medscape Medical News
An ambitious plan to sequence large numbers of cancer genomes is underway, under the auspices of the International Cancer Genome Consortium. Although the proposal has already stirred up some controversy and will be expensive, the scientists involved argue that this is a "deliverable project that will comprehensively elucidate central questions relating to the nature of human cancer." Subscription required.    E-mail article

Ill From Food? Investigations Vary by State
from The New York Times
In just about every major contaminated food scare, Minnesotans become sick by the dozens while few people in Kentucky and other states are counted among the ill. Contaminated peanuts? Forty-two Minnesotans were reported sick compared with three Kentuckians. Jalapeņo peppers last year? Thirty-one in Minnesota and two in Kentucky became ill. The different numbers arise because health officials in Kentucky and many other states fail to investigate many complaints of food-related sickness while those in Minnesota do so diligently, safeguarding not only Minnesotans but much of the rest of the country, as well. More    E-mail article

Pilot Study Finds Inexpensive Drug Appears To Relieve Fibromyalgia Pain
from Medical News Today
For Tara Campbell, the onset of her fibromyalgia began slowly with repeated sore throats, fevers and fatigue. By the time she was diagnosed, a year later, she had become so debilitated by flulike symptoms and exhaustion that she often couldn't get off the couch all day. Campbell was one of 10 women with fibromyalgia to take part in a small pilot study at Stanford University School of Medicine over a 14-week period to test the new use of a low dose of a drug called naltrexone for the treatment of chronic pain. More    E-mail article

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