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ASCLS eNewsBytes
July 28, 2009
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Chinese Experts Grow Live Mice from Skin Cells
from Reuters
Chinese researchers have managed to create powerful stem cells from mouse skin and used these to generate fertile live mouse pups. They used induced pluripotent skin cells, or iPS cells ‒ cells that have been reprogrammed to look and act like embryonic stem cells. Embryonic stem cells, taken from days-old embryos, have the power to morph into any cell type and, in mice, can be implanted into a mother's womb to create living mouse pups. More    E-mail article

Beckman Coulter

New Lab Test May Help Predict Acute Kidney Injury in Patients in Intensive Care
from Medscape Medical News
A new laboratory test for urine neutrophil gelatinaseľassociated lipocalin helps predict whether patients in intensive care will develop acute kidney injury, according to the results of a study in the Journal of the American Society of Nephrology. "As a stand-alone marker, urine NGAL performed moderately well in predicting ongoing and subsequent AKI," senior author T. Alp Ikizler, MD, from Vanderbilt University Medical Center in Nashville, Tenn., said in a news release. More    E-mail article

DNA Software, Inc. Awarded $2.5 Million in NIH Funding to Develop Pioneering Nucleic Acid-based Technologies
from FierceBiotech
DNA Software, Inc. has been awarded three Fast Track SBIR grants from the National Institutes of Health to develop original in silico technologies to predict 3D structures of RNA-based molecules, improve diagnostics via modified nucleotides, and model the reaction rates of DNA and RNA experiments. DNA Software, Inc. is a unique life sciences technology company that conducts original wet lab research, develops advanced bioinformatics tools, sells molecular biology software, offers structural biology services, and provides advanced scientific consulting. More    E-mail article

Vaccine-Preventable Diseases Kill More Americans than Car Wrecks
from WebMD
Diseases easily preventable by adult vaccines kill more Americans each year than car wrecks, breast cancer, or AIDS. Yet relatively few in the U.S. know much about these diseases -- and far too few adults get vaccinated, find surveys by the CDC and the National Foundation for Infectious Diseases. "It may surprise you to learn that over 50,000 adults die each year of diseases that are potentially vaccine preventable," the foundation's president-elect William Schaffner, MD, said recently. More    E-mail article

Selfish Gene Makes for a Nasty Virus
from Laboratory News
Scientists studying why parasites are not more harmful to their hosts have discovered that as the world becomes more connected so natural selection will favor more dangerous parasites. The team - from Oxford University - looked at why, in mathematical and computer models, parasites reduce their harmfulness to the host (virulence) so as not to run out of hosts to infect: a phenomenon termed 'self-shading'. More    E-mail article


Waters Drives Efficiency in the Clinical and Research Laboratory and Showcases New MassTrak Systems
from Life Science Leader Magazine
Waters Corporation is introducing clinical scientists to its expanded portfolio of new products for clinical and research laboratories including a new research use only kit for quantitative measurement of Tacrolimus, Sirolimus, Everolimus, and Cyclosporin A. The Waters MassTrak Immunosuppressants XE RUO Kit provides laboratories an alternative to immunoassay test kits for research laboratory analyses. This and other Waters system platform solutions for amino acid analysis and for vitamin D clinical research laboratories were on display recently at the AACC Annual Meeting and Clinical Lab Expo in Chicago. More    E-mail article

Agent Orange Linked to Heart Disease, Parkinson's
from The Associated Press
Medical researchers say there may be a link between exposure to the defoliant Agent Orange and other herbicides used during the Vietnam War and an increased chance of developing serious heart problems and Parkinson's disease. A study from the Institute of Medicine released Friday contains several caveats, but suggests there is a stronger connection than previously thought about the health risks to Vietnam veterans. More    E-mail article

A New Symptom of Swine Flu: Seizures
from the Los Angeles Times
Four children in Dallas have developed neurological symptoms caused by the new H1N1 influenza virus, commonly called swine flu. According to a report in the Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report, two boys age 7 and 10 developed seizures and two older boys, age 11 and 17, developed hallucinations, difficulty standing and slowed speech. The symptoms were most likely caused by swelling and inflammation of the brain produced by the virus. More    E-mail article

Genetic Variant Linked to Improved Survival in Leukopenic HIV-Positive Blacks
from Reuters via Medscape Medical News
New research indicates that the null state (-46C/C genotype) of the Duffy Antigen Receptor for Chemokines, which is linked to malaria resistance, confers a survival advantage for HIV-infected African Americans with leukopenia. Lower white blood cell counts have been linked to faster HIV disease progression and persons of African ancestry typically have lower counts than those of European descent. However, in many persons of African ancestry, leukopenia is associated with a slower disease course compared with the counterparts of European descent. The basis for this difference was unclear. More    E-mail article

Hemoglobin A1c Changing Diagnosis of Diabetes
Over the past two decades hemoglobin A1c (HbA1c) has become an accepted and reliable measure of long-term glycemic control in diabetics, but glucose remained the "gold standard" when it came to diagnosing diabetes. Now, however, a new study from the International Expert Committee (IEC) recommends the use of HbA1c rather than glucose for diagnosis of diabetes. More    E-mail article

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