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Home    About    Scholarships    Meetings    Publications    Resources Aug. 3, 2010
ASCLS eNewsBytes
Aug. 3, 2010
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Breast density accounts for most of reduced mammogram sensitivity in younger women
Medscape Medical News    Share   Share on FacebookTwitterShare on LinkedinE-mail article
Poorer outcomes from conventional mammography screening of women in their 40s are primarily a result of sensitivity limits of the technology, rather than tumor biology, suggest authors of a study published in the Journal of the National Cancer Institute. Nearly 80 percent of the difference between outcomes in younger versus older women is accounted for by the inability of mammography to detect small tumors in the breast tissue of younger women, and about 20 percent is accounted for by faster tumor-volume doubling times, report Sylvia K. Plevritis, PhD, and colleagues from the Department of Radiology at Stanford University School of Medicine in California. More

Vertebrate genomes hide ancient viruses
NPR    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Reporting in the journal PLOS Pathogens, researchers write opossums have bits of the Ebola virus mixed into their genetic code and human genomes contain snippets of the Borna virus. Study author Anna Skalka says some of the virus genetic code was inserted 40 million years ago. More

FDA clears rapid point-of-care bilirubin test for newborns
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The U.S. Food and Drug Administration has granted 510(k) clearance to market the first-ever, rapid point-of-care, laboratory-quality blood test for measuring total bilirubin in newborns (tBili assay; Instrumentation Laboratory). Performed on the company's automated GEM Premier 4000 critical care analyzer, the total bilirubin assay provides on-the-spot results in 90 seconds, avoiding the hour-long wait for results from a laboratory using traditional chemistry methods. More

Embryonic stem cells cleared for pilot tests in paralyzed patients
USA Today    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Federal officials have cleared a first human embryonic stem cell treatment for experiments on paralyzed patients, a biomedical firm announced. The Food and Drug Administration approval for the Geron Corp. of Menlo Park, Calif., to begin pilot experiments using the "GRNPOC1" line of human embryonic stem cell to treat patients with mid-spine injuries comes after years of applications. The approval ends a January hold on the experiment after animals in tests developed cysts at injection sites, resulting in Geron developing new monitoring measures and promising added safety steps for their experiments. More

Third case of Legionnaires' disease confirmed
The Detroit Free Press    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A third person was diagnosed with Legionnaires' disease following a bacterial outbreak that sickened 31 people at Selfridge Air National Guard Base in Harrison Township, Mich., officials there confirmed. The latest case involves a civilian employee at Warren-based TACOM Life Cycle Management Command, one of the U.S. Army's largest weapons researchers and developers. More

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Celiac disease diagnosis up 4-fold worldwide
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Studies from the United States, Europe, and elsewhere indicate that the prevalence of celiac disease (CD) has increased significantly in the last three decades — possibly by as much as a factor of 4. "More and more studies indicate a prevalence of CD of more than 1 percent in both adults and children. This should be compared with lower prevalence figures [from] 20 to 30 years ago," Jonas Ludvigsson, MD, from the Department of Medicine, Epidemiology Unit, at the Karolinska Institute and Orebro University Hospital, Sweden, and an expert in CD, noted in an e-mail to Medscape Medical News. More

Red blood cells have a tiny but effective protector — microRNA
Cell Biology via Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Pediatric researchers have discovered a new biological pathway in which small segments of RNA, called microRNA, help protect red blood cells from injury caused by chemicals called free radicals. The microRNA seems to have only a modest role when red blood cells experience normal conditions, but steps into action when the cells are threatened by oxidant stress. Led by hematologist Mitchell Weiss, M.D., Ph.D., of The Children's Hospital of Philadelphia, the current study describes how a particular microRNA fine-tunes gene activity by acting on an unexpected signaling pathway. More

New cellular 'armor' developed to prevent infection by AIDS virus
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Research has led to the development of a novel method of attack against the AIDS virus. The method involves creating a prevention system, i.e. an 'armour' in the cells that are likely to be infected and thus impede the virus from accessing them and starting to act on their immunological system. More
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