This message contains images. If you don't see images, click here to view.
Click here to advertise in this news brief.

  Mobile version   RSS   Subscribe   Unsubscribe
Home    About    Scholarships    Meetings    Publications    Resources    Join ASCLS Oct. 4, 2011
ASCLS eNewsBytes
Oct. 4, 2011
ASCLS Quick Links >   Home    About    Scholarships    Meetings    Publications    Resources

Prominent inherited disease expert Dr. James Bowman dies
Reuters    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Inherited disease expert Dr. James Bowman, who challenged the ethics of genetic screening has died at age 88, the University of Chicago said. Bowman, an internationally recognized African-American pathologist and expert on inherited blood diseases such as sickle cell anemia, died from cancer, the school said. More
Related story:
Dr. James E. Bowman, 1923-2011   (Chicago Tribune)

Computational modeling can help plan vaccine introduction
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Proper planning before the introduction of new vaccines into a developing country's active immunization program could prevent storage problems and transportation bottlenecks that decrease the availability of existing vaccines by as much as two-thirds, according to a University of Pittsburgh study. Computational models can assess the evolving needs of the vaccine supply chain – or the series of steps required to get a vaccine from the manufacturer to the target population. More

Preoperative chlorhexidine wash superior to povidone-iodine
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Using chlorhexidine as a preoperative surgical wash cut the risk for a surgical site infection in half, compared with washing with 10 percent povidone-iodine, investigators from the Singapore General Hospital reported at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy. Chlorhexidine and povidone-iodine, both used preoperatively to reduce SSIs, have similar spectra of bactericidal activity, but differences in their effectiveness in eradicating microbes have been reported. Investigators, led by pharmacist Yixin Liew, performed a meta-analysis to evaluate the effectiveness of a chlorhexidine bath in reducing the rate of SSIs. More

Survey set to measure impact of trend by urologists and GIs to create their own in-office anatomic pathology laboratories
DarkDaily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
One trend reshaping the profession of anatomic pathology with surprising speed is the growth of in-clinic pathology laboratories by specialist physicians. As each office-based physician group builds its own in-clinic pathology laboratory, local pathology groups and medical laboratories lose access to the tissue specimens these doctors now process in their own pathology lab. This trend has significant consequences for the nation's 3,300 pathology group practices, as well as those national pathology and clinical laboratory companies that compete for the biopsy tissue referrals of office-based physicians. Losing access to the tissue referrals of local physicians makes it tougher for local pathologists to develop a broad range of experience and skills. More

Scientists develop way to rapidly produce stem cells
Laboratory Equipment    Share    Share on FacebookTwitterShare on LinkedinE-mail
Scientists have found a way to rapidly produce pure populations of cells that grow into the protective myelin coating on nerves in mice. Their process opens a door to research and potential treatments for multiple sclerosis, cerebral palsy and other demyelinating diseases afflicting millions of people worldwide. More

STA Coag ConneXion

STA Coag ConneXion is an easy to use, Windows 7 based user interface that offers comprehensive QC management, remote QC capability and standardized result reporting with the use of expert rules for auto validation. For more information on STA Coag ConnneXion, visit

Response to EGFR inhibitors: Are more mutations better?
Medscape Genomic Medicine    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Investigators in China examined tumor samples from 100 patients with lung cancer to determine whether the quantity of epidermal growth factor receptor mutations within a lung cancer influences the clinical activity of an EGFR tyrosine kinase inhibitor. All patients had received gefitinib at some point during the course of their disease, either as part of a clinical trial or in clinical practice; the tissue samples retrieved from the tissue bank had been obtained at diagnosis. More

Rare flu-like virus on the rise
Agence France-Presse    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A rare virus has killed three people and sickened nearly 100 in Japan, the Philippines, the United States and the Netherlands over the past two years, U.S. health authorities said. The culprit is human enterovirus 68, and its respiratory symptoms can be particularly dangerous to children, the U.S. Centers for Disease Control and Prevention said in its Morbidity and Mortality Weekly Report. More

Researchers kill breast cancer cells with virus
QMI Agency via London Free Press    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A non-disease-causing virus has been found to kill breast cancer cells in a lab setting, researchers say. The discovery could lead to new cancer therapies. In tissue culture dishes in the laboratory, the virus destroyed 100 percent of the cancer cells within seven days, the researchers found. More

Study: Genomic architecture presages genomic instability    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers at Baylor College of Medicine who study families with such genomic disorders have found a shared, yet unusual, architecture resulting from this jumble that is associated with very severe forms of disease. They also identified the genomic elements that produce such architecture, a finding that will help predict other unstable regions in the human genome. More

A breath of fresh air in diagnostics

Providing the accurate, dependable allergy, urinalysis and auto-immune results you require. Delivering the cost-effective test results you value.

Levels of modified DNA base pairs examined in cells
Johns Hopkins News-Letter    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers have found that 5-hydroxymethylcytosine content closely correlates with the differentiation state of cells. Terminally differentiated cells contain the highest levels of 5hmC, while less differentiated stem/progenitor cell compartments exhibit very low levels. In addition, 5hmC levels are significantly reduced in prostate, breast and colon carcinomas as compared to normal tissues, a finding which sheds some light on the characteristics that enable cancer cells to survive. More

Role identified for cancer-related genetic elements in glucose metabolism and type 2 diabetes
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A role for genetic elements previously implicated in cancer progression has been found in the regulation of metabolism, insulin sensitivity, and the development of diabetes. The RNA-binding proteins Lin28a/b have been shown to promote malignancy by inhibiting let-7 biogenesis, but studies in experimental mice have now demonstrated that overexpression of Lin28a or human LIN28B in mice promotes insulin sensitization that makes the animals resistant to developing high fat diet-induced diabetes. More

1st Test Kit Cleared to Monitor Lung Cancer

Fujirebio Diagnostics, Inc. introduces the first FDA cleared test to be used as an aid in monitoring disease progression during the course of disease and treatment in lung cancer patients. MORE

'Autistic' mice created — and treated
New Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new strain of mice engineered to lack a gene with links to autism displays many of the hallmarks of the condition. It also responds to a drug in the same way as people with autism, which might open the way to new therapies for such people. It's not the first mouse strain to have symptoms of autism, and previous ones have already been useful models for studying the condition. More

All-access genome: New study explores packaging of DNA
ScienceDaily    Share    Share on FacebookTwitterShare on LinkedinE-mail
While efforts to unlock the subtleties of DNA have produced remarkable insights into the code of life, researchers still grapple with fundamental questions. For example, the underlying mechanisms by which human genes are turned on and off — generating essential proteins, determining our physical traits, and sometimes causing disease — remain poorly understood. More
Triturus - True Open Flexibility
As a leader in fully automated immunoassay testing systems, Grifols USA Diagnostic Division’s premier product, the TRITURUS® ELISA System is an open, fully automated, multi-test and multi-batch immunoassay system. Grifols USA is a major distributor of quality IVD ELISA tests for Infectious Disease, Autoimmune Diseases and many other disease states. Grifols’ Diagnostic products take the complexity out of clinical diagnostic testing.

CellaVision Automates and Standardizes the Manual Differential

CellaVision introduces CellAtlas®, the perfect way to learn the basics of hematology cell morphology. This App for the Apple iPhone and iPod Touch compliments our digital cell morphology portfolio, and is an educational tool to assist in the recognition and classification of blood cells, by utilizing mini-lectures and cell quizzes. More
Trust in Cleveland Clinic Laboratories
Cleveland Clinic Laboratories is a full-service, national reference lab dedicated to providing world class care. We have a dedicated staff of more than 1,300 employees, including board-certified subspecialty pathologists, PhDs, technologists, technicians, and support personnel. Cleveland Clinic Laboratories is proud to serve hospitals, outpatient facilities and physician offices worldwide. For more information, please visit
This edition of the ASCLS eNewsBytes was sent to ##Email##. To unsubscribe, click here.

Did someone forward this edition to you? Subscribe here - it's free!


Colby Horton, Vice President of Publishing

Download Media Kit

To contribute news to the ASCLS eNewsBytes, contact Yvette Craig, Senior Content Editor

Recent Issues

  • Sept. 27, 2011
  • Sept. 20, 2011
  • Sept. 13, 2011
  • Sept. 6, 2011
  • Aug. 30, 2011
  •  RSS Feed
    Most popular articles