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Nov. 1, 2011
Nov. 1, 2011
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Screening for thyroid disease in pregnancy cost-effective
American Thyroid Association via Medscape    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The universal screening of pregnant women for thyroid disease is highly cost-effective in light of the variety of potential adverse events for the mother and child, according to research presented at the American Thyroid Association 2011 Annual Meeting. Although the American Academy of Clinical Endocrinologists endorsed universal screening of pregnant women for thyroid dysfunction in 2002, other major organizations, including the ATA and the Endocrine Society, currently recommend screening only for high-risk women, despite numerous risks associated with the disease, said lead author Chrysoula Dosiou, Ph.D., from the Stanford University School of Medicine Division of Endocrinology in Palo Alto, Calif. More

More medical lab testing expected as retail clinics change delivery of routine healthcare services
Dark Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Retail clinics — or rapid clinics — are growing at a phenomenal rate. At the same time, more hospitals and health systems are deciding to participate in this growing trend, either by owning and operating such retail clinics in their communities or by providing the clinical staff. Pathologists and clinical laboratory managers should expect to see, over time, a steady increase in the menu of diagnostic testing offered by retail clinics. More

Gene sequencing X Prize to focus on centenarians
Reuters    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A $10 million contest to see which laboratory can accurately and economically sequence 100 human genomes has been tweaked to focus on the genetics of people over the age of 100. The competition, now sponsored by drug benefit manager Medco Health Solutions Inc, is aimed at achieving a "medical grade" standard for gene sequencing that could ultimately be used to personalize medical treatment based on a person's genetic makeup. More
Related story:
Why do some people live past 100? Genome may hold clues to longevity   (PBS NewsHour)

Oncolytic virus kills tumor in triple-negative breast cancer
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Laboratory studies conducted at the Memorial Sloan-Kettering Cancer Center in New York City suggest that triple-negative breast cancer might respond to treatment with an oncolytic agent. The findings were reported at the American College of Surgeons 97th Annual Clinical Congress. "We found that (the mutant herpes virus) NV1066 is an effective oncolytic agent against triple-negative breast cancer in vitro and in vivo," said Sepideh Gholami, MD, a research fellow in the laboratory of Yuman Fong, MD, which is considered to be at the forefront in oncolytic viral therapy research. More

Scientists work on synthetic blood to end shortages
NewsCore via Fox News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Artificial blood made from human stem cells will be tested in clinical trials in Britain within three years and could be used routinely in hospitals within a decade, according to Scottish scientists. It is hoped that manufactured blood derived from adult bone marrow or embryonic stem cells could end blood shortages caused by too few donors. More

Antiretroviral-based microbicides and oral pre-exposure prophylaxis for HIV prevention
Future Virology via Medscape    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Numerous HIV prevention options have been tested, with limited success. Microbicides have been the focus of research specifically targeted to prevent new infections among women. After decades of research using non-HIV-specific microbicides, we now have proof of concept for antiretroviral-based microbicides. Issues of drug resistance, frequency of HIV testing and adherence to treatment remain to be explored. More

STA Coag ConneXion

STA Coag ConneXion is an easy to use, Windows 7 based user interface that offers comprehensive QC management, remote QC capability and standardized result reporting with the use of expert rules for auto validation. For more information on STA Coag ConnneXion, visit

Penn scientists: Lab-made skin cells will aid transplantation, cancer, drug discovery research
Penn Medicine    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The pigmented cells called melanocytes aren't just for making freckles and tans. Melanocytes absorb ultraviolet light, protecting the skin from the harmful effects of the sun. They also are the cells that go haywire in melanoma, as well as in more common conditions as vitiligo and albinism. Naturally, researchers would love to study melanocytes in the laboratory. There's just one problem — melanocytes from adult skin don't grow very well in the lab. Now, researchers at the Perelman School of Medicine at the University of Pennsylvania have found a way to create melanocytes from mouse tail cells using embryonic stem cell-like intermediates called inducible pluripotent (iPS) cells. More

Salmonella linked to pine nuts sickens 42
Reuters    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Wegmans Food Markets Inc. is recalling Turkish pine nuts linked to a salmonella outbreak that has made 42 people ill in six states, health authorities reported. The pine nuts were sold in the bulk foods departments of most Wegmans stores in New York, Pennsylvania, New Jersey, Virginia, and Maryland between July 1 and Oct. 18, the Rochester, N.Y., company said in a statement on the Food and Drug Administration website. More

Study shows PNA FISH test reporting decreases mortality and hospital costs
ADVANCE for Administrators of the Laboratory    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new study documents significant decreases in ICU mortality and hospital costs for patients with bloodstream infections after implementation of PNA FISH tests for rapid identification of bloodstream pathogens. The study was performed at The University of Arizona Medical Center-University Campus in a collaboration between the clinical microbiology laboratory and infectious diseases pharmacists as part of the institution's Antimicrobial Stewardship Program More

Regenerated lungs from stem cells bring possible therapy
The International Business Times    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Severe cases of the flu can trash lungs, leaving patients gasping for breath. In a first, researchers used regenerative stem cells to repair fragile damaged lungs in mice previously infected by a nasty strain of H1N1 influenza. The results could lead to new therapies for asthma, chronic bronchitis and emphysema in humans. More

A breath of fresh air in diagnostics

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Clinical pathology laboratories should expect more direct-to-consumer testing
DarkDaily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In an interesting twist on the direct-to- consumer diagnostic testing market, QuickCheck Health is developing a DTC testing platform that brings clinician oversight into the process. Most pathologists and clinical laboratory managers know that over-the-counter testing is one of the faster growing market segment of in vitro diagnostics. A number of OTC products—including tests for urinary tract infections, pregnancy, ovulation, fertility, HIV, and other conditions—are already on the market, stated an article in Technology Review. More

From gene testing to the bedside
Journal of the National Cancer Institute via Medscape    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In mid-June, the payment contractor for Medicare in California agreed to reimburse oncologists for using a diagnostic test that relies on gene expression profiling to classify undifferentiated metastatic tumors with unknown sites of origin. Such tumors occur in about 30,000 new cancer cases each year. More
Triturus - True Open Flexibility
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CellaVision Automates and Standardizes the Manual Differential

CellaVision introduces CellAtlas®, the perfect way to learn the basics of hematology cell morphology. This App for the Apple iPhone and iPod Touch compliments our digital cell morphology portfolio, and is an educational tool to assist in the recognition and classification of blood cells, by utilizing mini-lectures and cell quizzes. More
Trust in Cleveland Clinic Laboratories
Cleveland Clinic Laboratories is a full-service, national reference lab dedicated to providing world class care. We have a dedicated staff of more than 1,300 employees, including board-certified subspecialty pathologists, PhDs, technologists, technicians, and support personnel. Cleveland Clinic Laboratories is proud to serve hospitals, outpatient facilities and physician offices worldwide. For more information, please visit
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