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Nov. 15, 2011
Nov. 15, 2011
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US Oks therapy using human cord blood cells
Reuters    Share    Share on FacebookTwitterShare on LinkedinE-mail article
U.S. drug regulators have for the first time approved a therapy that uses cells of human blood from the placenta and the umbilical cord to treat people with blood-forming disorders or cancer. Those blood-forming types of cells, known as progenitor cells, are infused into patients and make their way to bone marrow, where they divide and mature. As they move into the bloodstream, they can help build new blood cells or restore their capacities, including immune function. More

Slow start for bundled-payment pilot bodes ill for reform
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new study published in Health Affairs throws cold water on the notion that healthcare reform can quickly replace the fee-for-service system, and all its attendant problems, with new models of reimbursement that reward the quality of care while lowering costs. Lead author Peter Hussey, Ph.D., and coauthors reached that conclusion after studying a private-sector pilot project to bundle payments for a defined episode of care, such as hip replacement, as opposed to reimbursing hospitals, physicians, and other providers on a piecemeal basis that encourages wasteful care. More

Hospitals, physicians and clinical pathology laboratories scramble to prepare for use of Form 5010 beginning Jan. 1
Dark Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Less than eight weeks remain before the Jan. 1, deadline for implementation of Form 5010. Every sector of the healthcare system — from government and private payers to hospitals, physicians, pathologists, and clinical laboratories — is involved in this important healthcare reform. Many providers and payers are scrambling to meet the Health Insurance Portability and Accountability Act (HIPAA) version 5010 compliance deadline. This is the latest version of standards for the conversion of electronic health records. More

SNaPshot: Screening for many mutations at once
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Sending off a tumor sample for a broad screening of genetic aberrations, instead of just a single test, increases the chance of finding a therapy that the patient will respond to, and it might also improve survival, say researchers from Massachusetts General Hospital, in Boston, who are already using the screen in routine clinical practice. More

Lipids and lipoproteins
Clinical Laboratory News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The Centers for Disease Control and Prevention has worked for more than 50 years to standardize lipid and lipoprotein measurements to improve public health. Early efforts focused on developing a reference system, including reference measurement procedures and reference materials to use in the Lipid Standardization Program. Not only has this important infrastructure program permitted comparisons of clinical and epidemiological studies, but it has also allowed researchers to recognize long-term population trends in lipids and lipoproteins. More

Medicinal herb linked to endemic nephropathy and cancer
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
An endemic nephropathy found in Eastern European farming communities appears to be caused by environmental exposure to the human carcinogen aristolochic acid, a major component of an herb used in Chinese medicine, according to a study published online in Kidney International. More

Cholesterol key to 'sneaky' HIV weakness
Laboratory News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Removing cholesterol from the membrane surrounding the HIV virus could point to a new method of preventing the virus from damaging the immune system. Researchers from Imperial College London and Johns Hopkins University found that removing cholesterol from the cell membrane stopped HIV from triggering the innate immune response, which some researchers believe overreacts and weakens the adaptive immune response. More

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Computer 'pathologist' could assess breast cancer survival
HealthDay via USA Today    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new computer model analyzes microscopic breast cancer images and predicts patient survival better than the pathologists who do the job now, new research suggests. The computer program "provides information above and beyond what the physician provides, using the same data," said Daphne Koller, a professor of computer science at Stanford University and senior author of the study. The computer model is called Computational Pathologist, or C-Path. More

Palmetto, Medicare's biggest carrier, proposes to end code stacking for molecular clinical laboratory tests
Dark Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Medicare's biggest local carrier is ready to tackle the problems created when clinical pathology laboratories use code stacks to submit claims for genetic tests and molecular diagnostics assays. Medical laboratories in eight states served by this Medicare carrier are worried about its two draft proposals that could cut off reimbursement for large numbers of molecular diagnostic tests and laboratory-developed tests, starting Feb. 27. More

Malaria vaccine hope after blood entry route discovered
BBC News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The route all strains of the most deadly malaria parasite use to enter red blood cells has been identified by researchers at the Sanger Institute in Cambridge, England. The scientists involved said the finding offered "great hope" for the development of a vaccine, which had the potential to be hugely effective. More

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Disagreement common between point-of-care and core labs
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
There are significant differences in potassium measurements between point-of-care (POC) and core laboratory samples, according to a study presented at the American Society for Clinical Pathology 2011 Annual Meeting in Las Vegas. POC testing of electrolytes has increased because of faster turnaround time and the low sample volume requirements. However, the study investigators began receiving reports from clinicians that POC results didn't always match those from the core lab. More

Infection selection
The Scientist (Opinion)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Genomic sequencing of samples from multiple patients during a bacterial epidemic has revealed gene mutations that give the bugs a selective advantage. The large-scale sequencing approach, which is reported in Nature Genetics, should help researchers find chinks in the armor of a wide range of human pathogens. More

Study links Parkinson's disease to industrial solvent
BBC News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
An international study has linked an industrial solvent to Parkinson's disease. Researchers found a six-fold increase in the risk of developing Parkinson's in individuals exposed in the workplace to trichloroethylene (TCE). Although many uses for TCE have been banned around the world, the chemical is still used as a degreasing agent. More
CellaVision Automates and Standardizes the Manual Differential

CellaVision introduces CellAtlas®, the perfect way to learn the basics of hematology cell morphology. This App for the Apple iPhone and iPod Touch compliments our digital cell morphology portfolio, and is an educational tool to assist in the recognition and classification of blood cells, by utilizing mini-lectures and cell quizzes. More
Triturus - True Open Flexibility
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Trust in Cleveland Clinic Laboratories
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