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Nov. 29, 2011
Nov. 29, 2011
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Stopping the hospital spread of gram-negative bacilli
Infectious Diseases Society of America via Medscape    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In recognition of the CDC's 2011 Get Smart About Antibiotics Week, Dr. John Bartlett from Johns Hopkins University School of Medicine joins Dr. Alex Kallen from the Centers for Disease Control and Prevention to discuss stopping the spread of Gram-negative bacilli in U.S. hospitals. The Medscape podcast is a must-see for every doctor, nurse, and healthcare provider who work in an in-patient or outpatient hospital setting and are facing untreatable infections.

Genetic rearrangements drive 5 to 7 percent of breast cancers
ScienceDaily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers at the University of Michigan Comprehensive Cancer Center have discovered two cancer-spurring gene rearrangements that may trigger 5 to 7 percent of all breast cancers. These types of genetic recombinations have previously been linked to blood cancers and rare soft-tissue tumors, but are beginning to be discovered in common solid tumors, including a large subset of prostate cancers and some lung cancers. More

Delayed hemolytic transfusion reaction without detectable autoantibodies or alloantibodies
Medscape's Laboratory Medicine    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Delayed hemolytic transfusion reactions may occur when there is an antigen mismatch between transfused RBCs and recipient RBC antibodies where sensitized RBCs are cleared by macrophages or complement activation leading to immunoglobulin G mediated hemolysis. Some DHTR etiologies remain unknown since there are cases of DHTR when an RBC autoantibody or alloantibody is absent. Mechanisms have been proposed to explain these types of cases of DHTR, including bystander or reactive hemolysis by hyperactive macrophages. More

SNaPshot: Screening for many mutations at once
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Sending off a tumor sample for a broad screening of genetic aberrations, instead of just a single test, increases the chance of finding a therapy that the patient will respond to, and it might also improve survival, say researchers from Massachusetts General Hospital in Boston, who are already using the screen in routine clinical practice. The broad genetic screen, known as SNaPshot, is advertised around the hospital with a poster that depicts a fingerprint, declaring: "Our patients are unique. So are their tumors." More

The immune system has protective memory cells
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The immune system possesses a type of cell that can be activated by tissues within the body to remind the immune system not to attack our own molecules, cells and organs, UCSF researchers have discovered. The discovery is likely to lead to new strategies for fighting a range of autoimmune diseases — in which the immune system attacks and harms specific molecules and cells within us — as well as for preventing transplant rejection. More

STA Coag ConneXion

STA Coag ConneXion is an easy to use, Windows 7 based user interface that offers comprehensive QC management, remote QC capability and standardized result reporting with the use of expert rules for auto validation. For more information on STA Coag ConnneXion, visit

ASL-MRI promising for Alzheimer's diagnosis
Medscape Medical News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Arterial spin-labeled perfusion magnetic resonance imaging (MRI) can detect changes in brain function associated with Alzheimer's disease on par with 18-fluorodeoxyglucose positron emission tomography, according to two new studies. The researchers suggest that there is considerable qualitative and quantitative similarity between the two techniques, and confirm that regional cerebral blood flow closely parallels regional cerebral glucose metabolism. More

Evidence suggests HPV testing not superior to conventional pap tests
Medscape Education Clinical Briefs    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Cervical cancer screening by conventional cytology testing has reduced cervical cancer incidence and mortality rates, as noted by the International Agency for Research on Cancer in the 2005 IARC Handbook of Cancer Prevention. Alternative or adjunct methods for screening include liquid-based cytology and human papillomavirus (HPV) testing. More

A breath of fresh air in diagnostics

Providing the accurate, dependable allergy, urinalysis and auto-immune results you require. Delivering the cost-effective test results you value.

Beta-D-glucan assay
Medscape's Laboratory Medicine    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new fungal surrogate marker, (1–3)-β-D glucan, offers a noninvasive method for the potential surveillance and diagnosis of invasive fungal infections. Invasive fungal infections have long been associated with significantly high morbidity and mortality on hematology-oncology wards and recipients of either solid-organ or hematopoietic stem cell transplantation. The diagnoses of invasive fungal infections have historically been made difficult by the need for invasive methods. More

Navigating the waters of social networking
ADVANCE for Medical Laboratory Professionals (Column)    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The American Society for Clinical Laboratory Science is continuing to expand usage of social networking platforms. The goal is to provide all of our members with any information they could ever need about ASCLS, and to do so through their favorite means of communication whether that be our traditional publications and mail notices, member emails and website content, or Facebook posts, tweets, FourSquare check-ins, and blog posts, said Rebecca L. Rogers, chair of ASCLS Social Networking Task Force. More
CellaVision Automates and Standardizes the Manual Differential

CellaVision introduces CellAtlas®, the perfect way to learn the basics of hematology cell morphology. This App for the Apple iPhone and iPod Touch compliments our digital cell morphology portfolio, and is an educational tool to assist in the recognition and classification of blood cells, by utilizing mini-lectures and cell quizzes. More
Triturus - True Open Flexibility
As a leader in fully automated immunoassay testing systems, Grifols USA Diagnostic Division’s premier product, the TRITURUS® ELISA System is an open, fully automated, multi-test and multi-batch immunoassay system. Grifols USA is a major distributor of quality IVD ELISA tests for Infectious Disease, Autoimmune Diseases and many other disease states. Grifols’ Diagnostic products take the complexity out of clinical diagnostic testing.

Trust in Cleveland Clinic Laboratories
Cleveland Clinic Laboratories is a full-service, national reference lab dedicated to providing world class care. We have a dedicated staff of more than 1,300 employees, including board-certified subspecialty pathologists, PhDs, technologists, technicians, and support personnel. Cleveland Clinic Laboratories is proud to serve hospitals, outpatient facilities and physician offices worldwide. For more information, please visit
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